Results 41 to 50 of about 171,535 (264)
Autoinflammatiós kórképek = Autoinflammatory diseases [PDF]
, 2018 Absztrakt: Az autoinflammatiós szindrómák a veleszületett immunrendszert érintő, visszatérő szisztémás gyulladásos tünetekkel, súlyos szövődményekkel jellemezhető kórképek.
Mosdósi, Bernadett +3 more
core +1 more source
Spectrum of Genetic Autoinflammatory Diseases Presenting with Cutaneous Symptoms
Acta Dermato-Venereologica, 2020 Autoinflammatory diseases comprise a group of chronic disabling entities characterized by inflammation without the presence of infectious agents, auto-antibodies or antigen-specific T-cells. Many autoinflammatory diseases are caused by monogenic defects,
Hanna Bonnekoh +5 more
doaj +1 more source
Reumatismo, 2023 Adenosine deaminase 2 deficiency (DADA2) is a rare monogenic vasculopathy caused by loss-of-function homozygous or compound heterozygous mutations in ADA2, formerly CECR1 (cat eye syndrome chromosome region 1) gene.
A. Colangelo +5 more
doaj +1 more source
Therapy of autoinflammatory syndromes [PDF]
Journal of Allergy and Clinical Immunology, 2009 The therapy of autoinflammatory syndromes is an excellent example of the power of translational research. Recent advances in our understanding of the molecular and immunologic basis of this newly identified classification of disease have allowed for the application of novel, effective, targeted treatments with life-changing effects on patients ...
openaire +2 more sources
JAAD International, 2020 The pathogenic model of hidradenitis suppurativa is in the midst of a paradigm shift away from a disorder of primary follicular occlusion to an autoinflammatory keratinization disease.
John W. Frew, MBBS, MMed, MSc
doaj +1 more source
Arthritis Care &Research, EarlyView.Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu +2 more
wiley +1 more source
Adult-onset Still’s disease presenting with aseptic meningitis: a case report
Frontiers in ImmunologyAdult-onset Still’s disease (AOSD) is a systemic autoinflammatory disorder characterized by high spiking fever, evanescent rash, arthritis, sore throat, and lymphadenopathy. The pathogenesis of AOSD remains unclear.
Xiao-Fen Li +7 more
doaj +1 more source
Autoinflammatory keratinization diseases [PDF]
Journal of Allergy and Clinical Immunology, 2017 Inflammation caused by the hyperactivation of innate immunity due to genetic factors occasionally leads to inflammatory cutaneous keratinization diseases. Such inflammatory keratinization diseases with genetic autoinflammatory mechanisms are called “autoinflammatory keratinization diseases” (AiKDs). We proposed a four-part definition of AiKDs.
Akiyama, Masashi +3 more
openaire +3 more sources
Autoinflammatory diseases and the kidney
Immunologic Research, 2023 AbstractThe kidney represents an important target of systemic inflammation. Its involvement in monogenic and multifactorial autoinflammatory diseases (AIDs) vary from peculiar and relatively frequent manifestations to some rare but severe features that may end up requiring transplantation.
Mohamed Tharwat Hegazy +4 more
openaire +4 more sources
Autoinflammatory diseases: a possible cause of thrombosis? [PDF]
, 2015 Autoinflammatory diseases are a group of disorders due to acquired or hereditary disfunction of innate immune system and characterized by systemic or localized manifestations. The prototype is Familial Mediterranean Fever, a monogenic hereditary disorder,
Manna, Raffaele +4 more
core +1 more source