Results 31 to 40 of about 181,043 (245)
Autoinflammatory Features in Gouty Arthritis [PDF]
, 2021 In the panorama of inflammatory arthritis, gout is the most common and studied disease. It is known that hyperuricemia and monosodium urate (MSU) crystal-induced inflammation provoke crystal deposits in joints.
Sara Bindoli +9 more
core +1 more source
Monogenic autoinflammatory diseases [PDF]
Rheumatology, 2014 During the past 15 years, a growing number of monogenic inflammatory diseases have been described and their respective responsible genes identified. The proteins encoded by these genes are involved in the regulatory pathways of inflammation and are mostly expressed in cells of the innate immune system.
Ricardo A G, Russo, Paul A, Brogan
openaire +2 more sources
Myelodysplastic syndrome with trisomy 8 presenting periodic fever and multiple MEFV gene variants outside exon 10: a case report [PDF]
, 2023 Myelodysplastic syndrome is associated with the development of autoinflammatory conditions, such as recurrent fever, polymyalgia, arthralgia, and erythema.
Hanajiri, Ryo +10 more
core +1 more source
Emerging Role of Dipeptidyl Peptidase-4 in Autoimmune Disease
Frontiers in Immunology, 2022 Dipeptidyl-peptidase IV (DPP4), originally identified as an aminopeptidase in 1960s, is an ubiquitously expressed protease presented as either a membrane-bound or soluble form.
Jie Huang +7 more
doaj +1 more source
Canakinumab for the treatment of autoinflammatory very early onset- inflammatory bowel disease
Frontiers in Immunology, 2022 IntroductionTherapeutic options are critically needed for children with refractory very early onset inflammatory bowel disease (VEO-IBD). Our aim was to evaluate clinical response to canakinumab, an anti-IL-1β monoclonal antibody, in patients with VEO ...
Eliana Shaul +13 more
doaj +1 more source
A rare case of an NLRP12-associated autoinflammatory disease
, 2021 Pathogenic variants in nucleotide-binding oligomerization-like receptor protein 12 (NLRP12) have been recently suggested as possible causes of autoinflammatory syndromes and should be considered for the differential diagnosis in the patients presenting ...
Seven, Mehmet +6 more
core +1 more source
Autoinflammatory Diseases in Childhood
, 2020 Autoinflammatory diseases are characterized by recurrent fevers and clinical findings of impaired natural immunity and can involve various organ systems. The concept of autoinflammatory disease emerged after the definition of familial Mediterranean fever
KASAPÇOPUR, Özgür +4 more
core +1 more source
Polymyalgia rheumatica: an autoinflammatory disorder? [PDF]
, 2018 Polymyalgia rheumatica: an autoinflammatory ...
Matteo Piga +9 more
core +1 more source
Autoinflammatory Disease Reloaded: A Clinical Perspective [PDF]
, 2010 Our understanding of the etiology of autoinflammatory disease is growing rapidly. Recent advances offer new opportunities for therapeutic intervention and suggest that the definition of what constitutes an autoinflammatory disease should be ...
Aksentijevich, Ivona +2 more
core +1 more source
Autoinflammatory diseases: what is behind them and what is new? [PDF]
, 2023 Autoinflammatory diseases are characterized by bouts of systemic or localized inflammation in the absence of an infection. While some autoinflammatory diseases are caused by a single gene mutation, others have been shown to be multifactorial, involving a
Saade, Serena +2 more
core +1 more source