Results 101 to 110 of about 147,251 (203)

TREM‐1 Blockade Inhibits Inflammasome Activation and Pyroptosis: Novel Insights on the Role of TREM‐1 and Syk in Monosodium Urate Crystal‐Induced Inflammation

Immunology, Volume 178, Issue 2, Page 249-260, June 2026.
Schematic overview of the roles triggering receptor expressed on myeloid cells‐1 (TREM‐1) plays in monosodium urate (MSU) crystal‐induced inflammasome activation and IL‐1β secretion in gout arthritis. The present study provides novel data suggesting that blockade of TREM‐1 by LP17 attenuates MSU‐crystal‐induced inflammation through inhibition of ...
Yair Molad, Irina Lagovsky, Vitaly Kliminski   +2 more
wiley   +1 more source

Development and implementation of the international AIDA network spondylarthritis registry

Frontiers in Medicine
During the last decade, spondyloarthritis (SpA) has increasingly been considered a disease at the crossroads between autoimmunity and autoinflammation.
Valeria Caggiano, Valeria Caggiano, Antonio Vitale, Antonio Vitale, Andrea Hinojosa-Azaola, Guillermo Arturo Guaracha-Basañez, Piero Ruscitti, Paola Cipriani, Samar Tharwat, Samar Tharwat, Hanan M. Elberashi, Esraa E. Othman, Alessandro Conforti, Giancarlo Gimignani, Sukran Erten, Patrizia Barone, Maissa Thabet, Jurgen Sota, Jurgen Sota, José Hernández-Rodríguez, Verónica Gómez-Caverzaschi, Gaafar Ragab, Gaafar Ragab, Amina Maher, Ezgi Deniz Batu, Perla Ayumi Kawakami-Campos, Jiram Torres-Ruiz, Carla Gaggiano, Carla Gaggiano, Abdurrahman Tufan, Hamit Kucuk, Henrique A. Mayrink Giardini, Guiga Ahmed, Mehmet Akif Eksin, Lampros Fotis, Azadeh Shariat Panahi, Stefano Gentileschi, Stefano Gentileschi, Ibrahim A. Almaghlouth, Ibrahim A. Almaghlouth, Petros P. Sfikakis, George E. Fragoulis, Costanza Monterosso, Daniela Opris-Belinski, Soad Hashad, Nunzia Di Meglio, Nunzia Di Meglio, Cristian Sica, Cristian Sica, Bahar Özdemir Ulusoy, Alejandra de-la-Torre, Ewa Wiesik-Szewczyk, Katarzyna Rybak, Alberto Balistreri, Alberto Balistreri, Claudia Fabiani, Claudia Fabiani, Maria Antonietta Mazzei, Maria Antonietta Mazzei, Bruno Frediani, Bruno Frediani, Luca Cantarini, Luca Cantarini   +62 more
doaj   +1 more source

Evaluation of Serum Zonulin Levels and Intestinal Permeability in Hidradenitis Suppurativa Patients

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Hidradenitis Suppurativa (HS) is a chronic inflammatory skin disease. Zonulin is a signaling protein secreted by enterocytes that regulates the function of tight junction complexes and intestinal permeability. The levels of zonulin increase in the blood with the disruption of the intestinal barrier and it is used as a biomarker ...
Elif Çetinkaya, Mehmet Onur Gökalp, Harbiye Dilek Canat, Burak Ünlü, Osman Gökdeniz, Zafer Türkoğlu, Nazlı Caf, İbrahim Halil Yavuz   +7 more
wiley   +1 more source

ReCell Autologous Regeneration Techniques Combined With Traditional Chinese Medicine in the Treatment of Stable Vitiligo: A Retrospective Study

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background ReCell autologous cell transplantation demonstrates efficacy in vitiligo repigmentation. Traditional Chinese medicine, such as Quchong Banjiuju Pill, may synergize with ReCell to enhance results, though combined protocols remain underexplored. Aims This study evaluated the efficacy and safety of ReCell combined with Quchong Banjiuju
Qiao Chen, Xueya Tong, Chen Duan, Wenchao Zhang, Fei Long, Guojing Chang, Xiaohan Hu, Maoying Wei, Zhifei Liu   +8 more
wiley   +1 more source

Immune endotypes in tuberculosis: Keys to decoding disease complexity

Journal of Internal Medicine, Volume 299, Issue 6, Page 670-693, June 2026.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor, Julia Guthrie, Lina Davies Forsman, Andrew R. Di Nardo, Susanna Brighenti   +4 more
wiley   +1 more source

NLRP12-associated autoinflammatory disease in Chinese adult patients: a single-centre study. [PDF]

RMD Open, 2023
Miao J, Zhang J, Huang X, Wu N, Wu D, Shen M.   +5 more
europepmc   +1 more source

PECU: A multicenter study on pediatric patients with cold‐induced urticaria

Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
Abstract Background Cold‐induced urticaria (ColdU) is a rare chronic inducible urticaria that can cause systemic reactions, including cold‐induced anaphylaxis (ColdA), but pediatric data are limited. The aim of this study was to evaluate the clinical characteristics, comorbidities, management approaches, risk of anaphylaxis, and long‐term course of ...
Betul Gemici Karaaslan, Ozgen Soyoz, Figen Celebi Celik, Humeyra Akbas, Yakup Canitez, H. Ilbilge Ertoy Karagol, Beril Canan Aksoydan, Yagmur Hazal Sadirvan Oguzkaya, Gizem Uslu, Semiha Bahceci Erdem, Ummugulsum Dikici, Hilal Gungor, Handan Duman Senol, Hulya Anil, Adem Yasar, Lida Bulbul, Nursen Cigerci Gunaydin, Ozge Turkyilmaz Ucar, Mehmet Akif Kaya, Sanem Eren Akarcan, Tugba Arikoglu, Ozge Kangalli Boyacioglu, Hatice Eke Gungor, Merve Ocalan, Mahmut Dogru, Mahir Serbes, Nagihan Iskender, Mehmet Kilic, Mutlu Yuksek, Ozlem Yilmaz, Tuba Tuncel, Sefika Ilknur Kokcu Karadag, Zeynep Meric, Tuba Karakurt, Sezin Aydemir, Ugurcan Sayili, Fadil Ozturk, Ozlem Sancakli, Aysen Bingol, Mehmet Halil Celiksoy, Mustafa Atilla Nursoy, Aylin Kont Ozhan, Suna Asilsoy, Ozge Yilmaz, Dilek Ozcan, Isil Eser Simsek, Koray Harmanci, Esen Demir, Deniz Ozceker, Oner Ozdemir, Sukru Cekıc, Mustafa Arga, Ozlem Cavkaytar, Nazli Ercan, Arzu Bakirtas, Zeynep Ulker Altinel, Demet Can, Haluk Cokugras, Esra Yucel, Ayca Kiykim   +59 more
wiley   +1 more source

New retinal findings in NLRP3-associated autoinflammatory disease. [PDF]

Orphanet J Rare Dis, 2023
Wei Z, Yang Z, Li D, Zhang X, Li B, Zhao X, Yan W, Wu B, Wu N, Wang X, Yu W, Shen M.   +11 more
europepmc   +1 more source

Editorial: Autoinflammatory Keratinization Disease (AiKD)

Frontiers in Immunology, 2020
Masashi Akiyama, Valerio De Vita, Kazumitsu Sugiura   +2 more
doaj   +1 more source

Current understanding of the NLRC4 Inflammasome in autoinflammation and enterocolitis

Communications Biology
The NLRC4 inflammasome is a cytosolic immune sensor that detects bacterial virulence structures and rapidly initiates inflammatory responses. While tightly regulated NLRC4 activation is essential for host defense, genetic mutations that enhance NLRC4 ...
Yuhang Wang, Sivakumar Lingappa, Zizhen Kang   +2 more
doaj   +1 more source