Results 31 to 40 of about 165,261 (263)

Urinary CE-MS peptide marker pattern for detection of solid tumors [PDF]

, 2018
Urinary profiling datasets, previously acquired by capillary electrophoresis coupled to mass-spectrometry were investigated to identify a general urinary marker pattern for detection of solid tumors by targeting common systemic events associated with ...
Belczacka, Iwona, Frantzi, Maria, Jankowski, Vera, Latosinska, Agnieszka, Merseburger, Axel S., Metzger, Jochen, Mischak, Harald, Siwy, Justyna, Vlahou, Antonia   +8 more
core   +2 more sources

HLA Class I or Class II and Disease Association: Catch the Difference if You Can [PDF]

, 2017
The association of autoimmune diseases with HLA has been known for many decades. To date, however, the underlying mechanisms have not been fully understood. The recently introduced genome-wide association studies (GWAS) have suggested that several genes
Fiorillo, Mt, Paladini, F, Sorrentino, R., Tedeschi, V   +3 more
core   +10 more sources

Autoinflammatory Diseases in Childhood

Balkan Medical Journal, 2020
Autoinflammatory diseases are characterized by recurrent fevers and clinical findings of impaired natural immunity and can involve various organ systems. The concept of autoinflammatory disease emerged after the definition of familial Mediterranean fever
Mehmet Yıldız, Fatih Haşlak, Amra Adrovic, Kenan Barut, Özgür Kasapçopur   +4 more
doaj   +1 more source

Clinical and functional characterisation of a novel TNFRSF1A c.605T > A/V173D cleavage site mutation associated with tumour necrosis factor receptor-associated periodic fever syndrome (TRAPS), cardiovascular complications and excellent response to etanercept treatment. [PDF]

, 2008
Objectives: To study the clinical outcome, treatment response, T-cell subsets and functional consequences of a novel tumour necrosis factor (TNF) receptor type 1 (TNFRSF1A) mutation affecting the receptor cleavage site.
B H Belohradsky, C Dejaco, C Duftner, K Huss, M Herold, M Schirmer, P Lohse, S Stojanov   +7 more
core   +1 more source

Autoimmunity, Autoinflammation, and Infection in Uveitis [PDF]

, 2018
Funding/Support: No funding or grant support. Financial Disclosures: John V. Forrester has received an honorarium for lecturing from Janssen (London, UK). Lucia Kuffova has undertaken consultancy work for Abbvie (London, UK). Andrew D.
Dick, Andrew D., Forrester, John V., Kuffova, Lucia   +2 more
core   +4 more sources

The burgeoning field of innate immune-mediated disease and autoinflammation. [PDF]

, 2016
Immune-mediated autoinflammatory diseases are occupying an increasingly prominent position among the pantheon of debilitating conditions that afflict mankind.
McDermott, MF, Peckham, D, Savic, S, Scambler, T   +3 more
core   +1 more source

Toward an Inclusive, Congruent, and Precise Definition of Autoinflammatory Diseases

Frontiers in Immunology, 2017
Autoinflammatory disease was introduced as a concept in 1999, demarcating an entirely new group of diseases in clinical, immunological, and conceptual terms.
Per Wekell, Per Wekell, Stefan Berg, Stefan Berg, Anna Karlsson, Anders Fasth, Anders Fasth   +6 more
doaj   +1 more source

Induced Pluripotent Stem Cell-Derived Monocytes/Macrophages in Autoinflammatory Diseases

Frontiers in Immunology, 2022
The concept of autoinflammation, first proposed in 1999, refers to a seemingly unprovoked episode of sterile inflammation manifesting as unexplained fever, skin rashes, and arthralgia.
Takayuki Tanaka, Takayuki Tanaka, Takeshi Shiba, Yoshitaka Honda, Yoshitaka Honda, Kazushi Izawa, Takahiro Yasumi, Megumu K. Saito, Ryuta Nishikomori   +8 more
doaj   +1 more source

Autoimmune and autoinflammatory mechanisms in uveitis [PDF]

, 2014
The eye, as currently viewed, is neither immunologically ignorant nor sequestered from the systemic environment. The eye utilises distinct immunoregulatory mechanisms to preserve tissue and cellular function in the face of immune-mediated insult ...
A Amadi-Obi, A Arida, A Cortes, A Fox, A Jager, A Peters, A Rothova, AC Anderson, AD Dick, AD Dick, AD Dick, AD Dick, AD Dick, AD Dick, AD Dick, AG Commodaro, AG Commodaro, AJ St. Leger, AK Denniston, AK Denniston, AL Oberg, Andrew D. Dick, B Bodaghi, B Engelhardt, BJ Raveney, BJ Raveney, BJ Raveney, BS Sheridan, C Broderick, C Terrada, C-C Chan, CC Murphy, CEI Janssen, Chi-Chao Chan, CJ Calder, CJ Chu, CJ Chu, D Atan, D Atan, D Atan, D Atan, D Banerjee, D Luger, D Perra, DA Carter, DA Copland, DA Copland, DA Copland, DA Copland, DA Jabs, DC Wraith, DF Martin, DJ Hankey, DJ Kilmartin, DL Turner, E Furusato, EB Gouveia, EC Kerr, EC Kerr, ED Mandelcorn, EF Foxman, EF Remmers, EJ Wherry, F An, F Chen, G Geri, GJ Wright, GJ Wright, GR Wallace, H Keino, H Mielants, H. Nida Sen, HL Rosenzweig, HL Rosenzweig, HL Rosenzweig, HM Cherwinski, HN Sen, IJ Crane, J Bauer, J Candia, J Chen, J Correale, JA Todd, JB Fordham, JC Wei, JF Bach, JJ Kuiper, JP Sherlock, JT Rosenbaum, JV Forrester, JV Forrester, JV Forrester, JV Forrester, K Gocho, KG Anderson, KH Sonoda, KM Murphy, KM Murphy, L Jostins, L Mao, Lai Wei, Lindsay B. Nicholson, LK Grange, LK Mackay, LM Wakim, LM Wakim, LP Schewitz, LV Rizzo, M Chen, M Cordero-Coma, M Deckert, M Greter, M Khairallah, M Pepper, MC Jenmalm, MG Netea, MJ Mattapallil, MJ Robertson, MS Suttorp-Schulten, N Hashida, N Mizuki, N Taylor, N Yosef, NA Rao, O Tomkins-Netzer, P Kivisäkk, P Yang, P Zamiri, PA Kurz, PB Medawar, PP Sfikakis, R Banchereau, R Gold, R Plumlee Courtney, R Ramesh, R Shechter, R Zhang, R Zhou, RB Nussenblatt, RB Nussenblatt, RB Nussenblatt, RB Nussenblatt, RB Nussenblatt, Richard W. Lee, RJ Snelgrove, RK Agarwal, RM Hoek, Robert B. Nussenblatt, RP Nair, RR Caspi, RR Caspi, RR Caspi, RR Caspi, RW Darrell, RW Lee, RW Lee, RW Lee, RW Read, RW Read, S Horie, S Hou, S Hou, S Jawad, S Ohno, S Ooka, S Preston, S Sugita, S Sugita, S Sugita, S Sugita, S Yeh, S Zhang, SA Ramsey, SB Su, SC Bendall, SC Teoh, SJ Morrison, SL Masters, SM Islam, SM Sharma, SM Whitcup, SR Boyd, SR Taylor, SR Thurau, SR Thurau, SW McPherson, T Lambe, T Yoshimura, TA Manolio, TM Martin, U Kaufmann, VL Calder, W Chi, W Chi, WF Hickey, WW Soon, Y Fei, Y Kirino, Y Okunuki, Y Peng, Y Usui, YH Lee, Z Li, Z Tu   +203 more
core   +1 more source

Autoinflammatory diseases

Immunology Letters, 2014
Autoinflammatory diseases represent an expanding spectrum of genetic and non-genetic inflammatory diseases characterized by recurrent episodes of fever and systemic inflammation affecting the eyes, joints, skin, and serosal surfaces. Thus, these syndromes are recognized as disorders of innate immunity.
  +5 more sources