Results 141 to 150 of about 7,527 (184)
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Autologous Chondrocyte Implantation
Medicine & Science in Sports & Exercise, 2008Autologous chondrocyte implantation (ACI) is a treatment option for full-thickness chondral, or osteochondral injuries that are painful, debilitating, and progressive. Goals of surgery and rehabilitation include replacement of damaged cartilage with hyaline or hyaline-like structure, maintained durability to withstand knee intraarticular forces over ...
Cheryl L, Riegger-Krugh +3 more
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An overview of autologous chondrocyte implantation
The Journal of Bone and Joint Surgery. British volume, 2009Chondral damage to the knee is common and, if left untreated, can proceed to degenerative osteoarthritis. In symptomatic patients established methods of management rely on the formation of fibrocartilage which has poor resistance to shear forces. The formation of hyaline or hyaline-like cartilage may be induced by implanting autologous, cultured ...
P D, Gikas +3 more
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Failure of Autologous Chondrocyte Implantation
Sports Medicine and Arthroscopy Review, 2017Long-term results of autologous chondrocyte implantation and matrix-assisted autologous chondrocyte transplantation in the knee are satisfying, but not enough attention has been paid to the evaluation of failures. Thus, a systematic review of the literature was performed, underlining a failure rate in the 58 included articles of 14.9% among 4294 ...
Luca, Andriolo +4 more
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Molecular characterisation of chondrocytes in autologous chondrocyte implantation
International Journal of Molecular Medicine, 2004Autologous chondrocyte implantation (ACI) relies on the use of cultured cells. However, the biosynthetic profile of cultured chondrocytes is shown to be altered during in vitro expansion. The purpose of this study therefore, was to examine the cellular phenotype of chondrocytes cultured for ACI and to determine the apoptotic index of cells implanted ...
M H, Zheng +6 more
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Autologous Chondrocyte Implantation in the Adolescent Knee
American Journal of Sports Medicine, 2011Background Autologous chondrocyte implantation (ACI) has been shown to have favorable results in the treatment of symptomatic chondral and osteochondral lesions. However, there are few reports on the outcomes of this technique in adolescents. Purpose
Tim P Morris +2 more
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Autologous chondrocyte implantation
Operative Techniques in Orthopaedics, 2001Autologous chondrocyte implantation (ACI) has been performed in more than 4,500 patients and, when appropriately indicated, provides durable hyaline-like repair tissue with consistent clinical results. ACI is primarily indicated for full-thickness articular cartilage injuries of the femoral condyles and trochlea.
Brian J. Cole, Mike D'Amato
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Autologous chondrocyte implantation.
Clinical privilege white paper, 2012Articular cartilage lesions are common pathology in the knee joint. Treatment of these lesions (microfractures, mosaicplasty, ACI, MACI) must be individualised taking into account variables such as location and extent of the lesion, the patient´s activity level and economic cost. Matrix-induced autologous chondrocyte implantation (MACI) offers a series
Primitivo Gómez-Cardero +2 more
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Autologous Chondrocytes and Next-Generation Matrix-Based Autologous Chondrocyte Implantation
Clinics in Sports Medicine, 2017Focal chondral defects of the knee are common and can significantly impair quality of life. The autologous chondrocyte implantation technique has evolved over the past 20 years; the newest third-generation technique is matrix-induced autologous chondrocyte implantation.
Andreas Gomoll
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Autologous Chondrocyte Implantation in the Patella
American Journal of Sports Medicine, 2014Background: Cartilage defects in the patella are common, and a subset of patients does not respond to nonoperative measures. While most cartilage repair techniques have demonstrated good outcomes in the femoral condyles, the patellofemoral compartment poses special challenges.
Andreas Gomoll, , Jack Farr
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Autologous chondrocyte implantation in children and adolescents
Knee Surgery, Sports Traumatology, Arthroscopy, 2012AbstractPurposeAutologous chondrocyte implantation (ACI) is a well‐established treatment method for cartilage defects in knees. Age‐related grouping was based on expression data of cartilage‐specific markers. Specificities of ACI in the different populations were analysed.MethodsTwo hundred and sixty‐seven patients undergoing ACI in the knee between ...
Schmal, Hagen +5 more
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