Characterization of the major autolysin (AtlC) of Staphylococcus carnosus [PDF]
Background Autolysis by cellular peptidoglycan hydrolases (PGH) is a well-known phenomenon in bacteria. During food fermentation, autolysis of starter cultures can exert an accelerating effect, as described in many studies on cheese ripening. In contrast,
Maximilian Merz +3 more
doaj +5 more sources
Exploration of Human Skin Phageome to Reveal Endolysins and Novel Antimicrobial Peptides for Therapeutic Applications. [PDF]
This study uncovers diverse endolysins and novel antimicrobial peptides from the human skin phageome, highlighting their potential to target antibiotic‐resistant pathogens and disrupt virulence mechanisms, paving the way for next‐generation skin therapeutics.
Paul JK +6 more
europepmc +2 more sources
Dual glycosylation of wall teichoic acid modulates the O-antigen pattern and virulence in serovar 4b <i>Listeria monocytogenes</i>. [PDF]
Abstract Among the 14 serovars of Listeria monocytogenes (Lm), serovar 4b strains are the most predominant isolates linked to human listeriosis outbreaks‐a phenotype associated with their unique wall teichoic acid (WTA) decorated with galactose (Gal) and glucose (Glu).
Yao H +7 more
europepmc +2 more sources
Novel P335-like Phage Resistance Arises from Deletion within Putative Autolysin yccB in Lactococcus lactis [PDF]
Lactococcus lactis and Lactococcus cremoris are broadly utilized as starter cultures for fermented dairy products and are inherently impacted by bacteriophage (phage) attacks in the industrial environment.
Jenny Seiler +4 more
doaj +2 more sources
Biochemical characterization and X-ray structural and mutagenic analyses of the putative autolysin CdCwlT33800 catalytic domain from Clostridioides difficile [PDF]
Clostridioides difficile is a major pathogen of pseudomembranous colitis, and new antimicrobial agents are needed for its treatment. Autolysins are peptidoglycan-degrading enzymes that generally reorganize the cell wall during cell division but kill ...
Hiroshi Sekiya +3 more
doaj +2 more sources
Cell wall mechanical stress could coordinate septal synthesis and scission in Staphylococcus aureus [PDF]
Staphylococcus aureus divides by building a septum and then splitting into two daughter cells. Scission should be coordinated with septum completion to avoid cell lysis; however, it is not known how this is achieved, or what the relative roles of ...
Sheila Hoshyaripour +4 more
doaj +2 more sources
PRODIGIOSIN INDUCES AUTOLYSINS IN ACTIVELY GROWN Bacillus subtilis CELLS [PDF]
Prodigiosin produced by marine bacterium Vibrio ruber DSM 14379 exhibits a potent antimicrobial activity against a broad range of Gram positive and Gram negative bacteria. The mechanism of prodigiosin antimicrobial action, however, is not known.
Tjasa eDanevcic +4 more
doaj +3 more sources
Understanding How Staphylococcal Autolysin Domains Interact With Polystyrene Surfaces [PDF]
Biofilms, when formed on medical devices, can cause malfunctions and reduce the efficiency of these devices, thus complicating treatments and serving as a source of infection. The autolysin protein of Staphylococcus epidermidis contributes to its biofilm
Radha P. Somarathne +5 more
doaj +3 more sources
Endogenous cell wall degrading enzyme LytD is important for the biocontrol activity of Bacillus subtilis [PDF]
Autolysins are endogenous cell wall degrading enzymes (CWDEs) in bacteria that remodel the peptidoglycan layer of its own cell wall. In the Bacillus subtilis genome, at least 35 autolysin genes have been identified.
Luotao Wang +10 more
doaj +2 more sources
Cloning of Minor Autolysin of Streptococcus Pneumoniae
Background and Objective: Increased antibiotic resistant strains and inadequacy of current vaccines against pneumococcal infections necessitate the study of novel protein antigens.
Mahboobi, R +5 more
doaj +1 more source

