Results 51 to 60 of about 9,066 (195)

In vitro bactericidal and bacteriolytic activity of ceragenin CSA-13 against planktonic cultures and biofilms of Streptococcus pneumoniae and other pathogenic streptococci. [PDF]

PLoS ONE, 2014
Ceragenin CSA-13, a cationic steroid, is here reported to show a concentration-dependent bactericidal/bacteriolytic activity against pathogenic streptococci, including multidrug-resistant Streptococcus pneumoniae.
Miriam Moscoso, María Esteban-Torres, Margarita Menéndez, Ernesto García   +3 more
doaj   +1 more source

Structural Organization of the Major Autolysin from Streptococcus pneumoniae [PDF]

Journal of Biological Chemistry, 1996
LytA amidase is the best known bacterial autolysin. It breaks down the N-acetylmuramoyl-L-alanine bonds in the peptidoglycan backbone of Streptococcus pneumoniae and requires the presence of choline residues in the cell-wall teichoic acids for activity. Genetic experiments have supported the hypothesis that its 36-kDa chain has evolved by the fusion of
Usobiaga, P., Medrano, Francisco Javier, Gasset, M., García, J.L., Sáiz, José L., Rivas, Germán, Laynez, J., Menéndez, Margarita   +7 more
openaire   +3 more sources

The detection of altered penicillin-binding protein 2b, autolysin, and pneumolysin genes in Streptococcus pneumoniae colonizing the upper respiratory tract of healthy schoolchildren in Puducherry

Journal of Current Research in Scientific Medicine, 2019
Background: Infections due to Streptococcus pneumoniae are responsible for morbidity and mortality in a large proportion of children in developing countries where childhood vaccination has not been widely implemented. S.
Divya Suguna Jayakar, Noyal Mariya Joseph, Patricia Anitha, Reba Kanungo   +3 more
doaj   +1 more source

Pathogenic Mechanisms and Host Interactions in Staphylococcus epidermidis Device-Related Infection [PDF]

, 2017
Staphylococcus epidermidis is a permanent member of the normal human microbiota, commonly found on skin and mucous membranes. By adhering to tissue surface moieties of the host via specific adhesins, S.
Ahmed, Ahtinen, Akira, Akira, Al-Ishaq, Alexander, Alexander, Allgaier, Amin, An, Arciola, Arrecubieta, Baier, Bastos, Bennallack, Bi, Bialecka, Bjorkqvist, Boelens, Boelens, Bowden, Bowden, Brancatisano, Brennan, Brown, Brown, Burgey, Campoccia, Carvalhais, Cerca, Cerca, Cerca, Chambers, Cherifi, Cheung, Chokr, Christensen, Christner, Christner, Chugh, Claro, Claro, Claro, Coates, Cogen, Cogen, Cole, Collado, Costerton, Costerton, Dapunt, Dapunt, Dapunt, Darouiche, Del Pozo, den Dunnen, Dhople, Dhople, Diekema, Dominguez-Bello, Dong, Durantez, Ekkelenkamp, Farina, Ferreirinha, Foster, Foster, Fournier, Franca, Franca, Frank, Gilbert, Gilbert, Gill, Gordon, Grice, Gristina, Guenther, Gutierrez-Murgas, Hajjar, Hamza, Hamzeh-Cognasse, Harris, Hartford, Hassan, Hatakeyama, Hazenbos, Heilmann, Heilmann, Heilmann, Heilmann, Heim, Hell, Hellmark, Hirai, Hirschhausen, Hogan, Holland, Huang, Hussain, Isiklar, Iwase, Izano, Janek, Jensen, Jilka, Jimenez, Johns, Joo, Kahl, Khalil, Kim, Kishimoto, Knobloch, Kobayashi, Kocianova, Kong, Kretschmer, Kretschmer, Kristian, Kronforst, Laborel-Preneron, Lai, Lai, Lai, Lam, Lam, Lambe, Lankinen, Laure, Le, Lee, Li, Li, Los, Lovati, Lovati, Mack, Mack, Mack, Mack, Magrys, Majchrzak, Marmor, Mayberry-Carson, Mayberry-Carson, Meghji, Megyeri, Mehlin, Melzer, Mempel, Metsemakers, Meyle, Miragaia, Montanaro, Morath, Morgenstern, Morgenstern, Morgenstern, Moriarty, Moriarty, Myrvik, N'Diaye, Naik, Nair, Nair, Natsuka, Nguyen, Nilsdotter-Augustinsson, Ommori, Osmon, Otto, Otto, Otto, Paharik, Park, Park, Park, Patel, Patzakis, Percoco, Perks, Peschel, Petty, Pietrocola, Pinheiro, Pourmand, Prabhakara, Prabhakara, Puig-Verdie, Qin, Qin, Qin, Quinn, Raisz, Rautenberg, Redlich, Riool, Robertson, Rochford, Rogers, Rohde, Rohde, Rohde, Rolo, Sadovskaya, Salgado, Salgueiro, Sandiford, Satorius, Schafer, Schaffer, Scharschmidt, Scherr, Schommer, Sellman, Shahrooei, Shahrooei, Sharon, Shurland, Simojoki, Sinha, Somayaji, Spiliopoulou, Stanislawska, Stashenko, Strunk, Strunk, Sugimoto, Sullivan, Svensson, Svensson, Tan, Tavakkol, Teterycz, Tormo, Trampuz, Trampuz, Trampuz, Trouillet-Assant, Tucker, Turner, Usui, Valour, van Bergenhenegouwen, van de Kamp, van der Borden, Veenstra, Vernachio, Vuong, Vuong, Vuong, Vuong, Vuong, Wakabayashi, Wang, Wang, Wanke, Webster, Widerstrom, Widerstrom, Williams, Wilsson, Xia, Xu, Xu, Yan, Yang, Yano, Yao, Yoshimura, Young, Zaatreh, Zhai, Zhang, Zhu, Zimmerli   +276 more
core   +5 more sources

The effect of skin fatty acids on Staphylococcus aureus [PDF]

, 2014
Staphylococcus aureus is a commensal of the human nose and skin. Human skin fatty acids, in particular cis-6-hexadecenoic acid (C-6-H), have high antistaphylococcal activity and can inhibit virulence determinant production.
Albrecht, D., Cartron, M., Donat, S., Engelmann, S., Foster, S.J., Hurd, A., Kusch, H., Neumann, Y., Ohlsen, K.   +8 more
core   +3 more sources

The secreted staphylococcal biofilm protein Sbp forms biomolecular condensates in the presence of DNA

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Staphylococcus epidermidis is the leading cause of device‐related infections, primarily due to its ability to form biofilms, surface‐adherent bacterial communities that confer remarkable resistance to antibiotics and host defenses. Small basic protein, Sbp, is a 16‐kDa protein expressed by S.
P. Ethan Adkins, Alexander E. Yarawsky, Andrew B. Herr   +2 more
wiley   +1 more source

Staphylococcus aureus Colonization of the Mouse Gastrointestinal Tract Is Modulated by Wall Teichoic Acid, Capsule, and Surface Proteins. [PDF]

PLoS Pathogens, 2015
Staphylococcus aureus colonizes the nose, throat, skin, and gastrointestinal (GI) tract of humans. GI carriage of S. aureus is difficult to eradicate and has been shown to facilitate the transmission of the bacterium among individuals.
Yoshiki Misawa, Kathryn A Kelley, Xiaogang Wang, Linhui Wang, Wan Beom Park, Johannes Birtel, David Saslowsky, Jean C Lee   +7 more
doaj   +1 more source

Emerging Biomedical Engineering Therapies for Infected Diabetic Foot Ulcers: Toward Antibacterial Functionalization and Pathology‐Responsive Regulation

Small Science, Volume 6, Issue 1, January 2026.
Infected diabetic foot ulcer endangers patients with high amputation, disability, mortality risks, and heavy medical burdens. This review analyzes its pathogenic factors, the limitations of current treatments, the breakthroughs of responsive antimicrobial biomaterials, and the challenge of multifunctional biomaterial innovations for further developing ...
Yaqi Yao, Mengyi Huang, Yuetong Li, Yiqi Lin, Junjie Dong, Jianhang Du, Aixia Zhai, Changlong Bi, Luoyuan Li   +8 more
wiley   +1 more source

Immunogenic potential of biogenic vs. synthetic selenium nanoparticles in vaccine candidate against methicillin-resistant Staphylococcus aureus

Vaccine: X
MRSA-related antimicrobial-resistant infections are a significant public health issue. Vaccination can prevent infection by inducing pathogen immunity. The surface-associated protein autolysin is a promising vaccination candidate. This study investigated
Alireza Ranjbariyan, Setareh Haghighat, Mohammad Hossein Yazdi, Sepideh Arbabi Bidgoli, Hedieh Moradi Tabriz, Mehdi Mahdavi   +5 more
doaj   +1 more source

The crystal structure of Pneumolysin at 2.0 Å resolution reveals the molecular packing of the pre-pore complex [PDF]

, 2015
Pneumolysin is a cholesterol-dependent cytolysin (CDC) and virulence factor of Streptococcus pneumoniae. It kills cells by forming pores assembled from oligomeric rings in cholesterol-containing membranes.
Andrew, Peter W, El-Mezgueldi, Mohammed, Faraj, Bayan H A, Gingras, Alexandre R, Lonnen, Rana, Marshall, Jamie E, Moody, Peter C E, Sheikh, Md. Arif, Wallis, Russell   +8 more
core   +1 more source