Results 131 to 140 of about 17,929 (235)
康复学报, 2016 Objective:To observe the effects of electroacupuncture (EA) at the Quchi (LI11) and Zusanli (ST36) acupoints on peri-infract striatal neural autophagy in middle cerebral artery occlusion (MCAO) -induced ischemia and reperfusion injured rats.Methods ...
Weilin LIU, Yunjiao LIN, Jing TAO
doaj
eLifeHuntington’s disease (HD) is caused by the expansion of the polyglutamine stretch in huntingtin protein (HTT) resulting in hallmark aggresomes/inclusion bodies (IBs) composed of mutant huntingtin protein (mHTT) and its fragments. Stimulating autophagy to
Philip Stavrides +8 more
doaj +1 more source
Az autofágiában szereplő kinázok és foszfatázok azonosítása in vivo RNSi teszteléssel ecetmuslicában = An in vivo RNAi screen of Drosophila kinases and phosphatases involved in autophagy [PDF]
, 2011 Az autofágia során a sejt saját citoplazmája kerül lizoszómális lebontásra és újrahasznosításra. Az éhezés a folyamat nagymérvű indukciójához vezet.
Juhász, Gábor
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Food Frontiers, Volume 7, Issue 3, May 2026.Saikosaponin A from Radix Bupleuri inhibited colorectal cancer HCT116 cells with low toxicity. SSA induced S/G2‐M cell cycle arrest and triggered autophagy via mTOR inhibition. SSA suppressed metastasis by blocking PI3K/AKT signaling pathway. SSA significantly reduced tumor growth without apparent toxicity.
Xiu‐Xiu Zhang +7 more
wiley +1 more source
SKD1 AAA ATPase-Dependent Endosomal Transport is Involved in Autolysosome Formation.
Cell Structure and Function, 2002 Mouse SKD1 AAA ATPase is involved in the sorting and transport from endosomes; cells overexpressing a dominant-negative mutant, SKD1(E235Q) were defective in endosomal transport to both the plasma membranes and lysosomes (Yoshimori et al., 2000). In the present study, we demonstrated that overexpression of SKD1(E235Q) using an adenovirus delivery ...
Atsuki Nara +5 more
openaire +3 more sources
Concanavalin A induced autophagy switches to apoptosis [PDF]
, 2014 Concanavalin A (Con A) is a lectin or carbohydrate binding protein having broad range of significant biological functions such as anti-tumor, anti-viral,anti-inflammatory, anti-proliferative activities.
Panda, Madhusmita
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Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.Bioengineered brain targeting RVG‐modified BMSCs‐derived small extracellular vesicles loaded with miR‐21 alleviate excessive autophagic neuronal injury after cerebral ischaemia via PTEN/Akt/mTOR pathway. ABSTRACT Ischaemic stroke (IS) leads to tragic disability and high adult mortality, while there are limited therapeutic measures for it.
Yiyang Li +9 more
wiley +1 more source
Nature CommunicationsRespiratory syncytial virus (RSV) hijacks cholesterol or autophagy pathways to facilitate optimal replication. However, our understanding of the associated molecular mechanisms remains limited.
Lifeng Chen +9 more
doaj +1 more source
Role of COL1A1 and CD44 in Modulating JAK1/STAT3‐Mediated Autophagy for Spinal Cord Injury Recovery
The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 5, May 2026.ABSTRACT Spinal cord injury (SCI) is a severe trauma to the central nervous system that often leads to motor and sensory dysfunction in patients, severely affecting their quality of life. Autophagy plays a role in the pathological process of SCI, but the specific mechanism of autophagy in this case is unknown.
Chun‐Lei Li +3 more
wiley +1 more source
Selective cell death of latently HIV-infected CD4+ T cells mediated by autosis inducing nanopeptides. [PDF]
, 2019 Despite significant advances in the treatment of human immunodeficiency virus type-1 (HIV) infection, antiretroviral therapy only suppresses viral replication but is unable to eliminate infection. Thus, discontinuation of antiretrovirals results in viral
Campbell, Grant R +6 more
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