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An Efficient Automated Radiosynthesis and Bioactivity Confirmation of VMAT2 Tracer [18F]FP-(+)-DTBZ
Molecular Imaging and Biology, 2019The aim of this study was to optimize the radiolabeling method of [18F]fluoropropyl-(+)-dihydrotetrabenazine ([18F]FP-(+)-DTBZ) to fulfill the demand of preclinical and clinical application.Optimized labeling conditions were performed by altering the molar ratio of precursor to base (P/B), base species, solvents, reaction temperature, reaction time ...
Chao Zhao +5 more
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Radiolabeled guanidines such as 123 / 131 I-labeled meta-iodobenzylguanidine ( m IBG) have been widely used in nuclear medicine for imaging of cardiac sympathetic nerves as well as the imaging and treatment of neuroendocrine ...
Jason A. Witek +8 more
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Jason A. Witek +8 more
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An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use. [PDF]
Journal of visualized experiments : JoVE[68Ga]Ga-FAPI-46 is a promising new tracer for the imaging of fibroblast activation protein (FAP) by positron emission tomography (PET). Labeled FAP inhibitors (FAPIs) have demonstrated uptake in various types of cancers, including breast, lung, prostate, pancreatic and colorectal cancer.
Morandeau, Laurence +7 more
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Fully Automated, High-Dose Radiosynthesis of [18F]PARPi
Pharmaceuticals, 2022Corentin Warnier +2 more
exaly
Fully automated radiosynthesis of [18F]SMBT-1 for clinical use
Nuclear Medicine and Biology, 2023Tetsuro Tago, Jun Toyohara, Kenji Ishii
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