Results 31 to 40 of about 536,697 (236)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

Zavodi “Crvena Zastava”: Yugoslav Self-Management Socialism and Challenges for the Automobile Industry

open access: yesEtnoantropološki Problemi, 2017
This paper explores the experience of the Zavodi “Crvena Zastava” (Red Flag factory) of building the Yugoslav automobile industry between 1950s and 1980s.
Milan J. Stanković
doaj   +3 more sources

Optimization of park-and-ride system: A case study of Shunyi in Beijing

open access: yesAdvances in Mechanical Engineering, 2017
Nowadays, rapid increase in automobile ownership results in traffic congestions especially in large cities all over the world. Park-and-ride mode could ease traffic congestion in urban areas without abandoning traffic demands.
Xiaopeng Shen   +4 more
doaj   +1 more source

Macroeconomic Resilience to Socioeconomic Challenges and Corporate Stability in the Automotive Industry: Impact on Dividend Policy [PDF]

open access: yesSocioEconomic Challenges
The study explains the relationship between macroeconomic and firm-affecting variables with dividend payout policy in the Indian automobile firms. A comprehensive dataset covering 18 Indian automobile manufacturing companies listed on the Bombay Stock ...
Rajat Mehrotra, Saurabh Chadha
doaj   +1 more source

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

open access: yesAdvanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch   +3 more
wiley   +1 more source

Benefits and Risks of the Driving Restriction Policy: A Case Study of Xi’an, China

open access: yesIEEE Access, 2020
With the deterioration of air pollution and traffic congestion especially in urban areas, the policy restricting cars operating on the road is deemed as an effective strategy to mitigate the negative impacts.
Zhuanglin Ma   +3 more
doaj   +1 more source

TRADITIONAL NEIGHBORHOODS AND AUTOMOBILE OWNERSHIP

open access: yes, 2002
Many cities have traditional neighborhoods composed of diverse housing, mixed land uses, pedestrian connectivity, and convenient transit access. The effects of these types of land use patterns on automobile ownership are quantified.
Ong, P M, Hess, D B
core   +1 more source

Composites of Shellac and Silver Nanowires as Flexible, Biobased, and Corrosion‐Resistant Transparent Conductive Electrodes

open access: yesAdvanced Functional Materials, EarlyView.
Shellac, a centuries‐old natural resin, is reimagined as a green material for flexible electronics. When combined with silver nanowires, shellac films deliver transparency, conductivity, and stability against humidity. These results position shellac as a sustainable alternative to synthetic polymers for transparent conductors in next‐generation ...
Rahaf Nafez Hussein   +4 more
wiley   +1 more source

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