Results 181 to 190 of about 73,321 (302)

Where and how do mammalian cells shape autophagosomes? [PDF]

J Biol Chem
Puri C, Rubinsztein DC.
europepmc   +1 more source

Rotenone Induces Morphological Damage and Reduction in Catecholamine Levels in the Central Nervous System of the Ascidian Styela plicata

Environmental Toxicology, EarlyView.
ABSTRACT Ascidians are invertebrates that occupy a key phylogenetic position as a sister group of the vertebrates. The organization of their central nervous system (CNS), with cortex and medulla, indicates a plesiomorphic character of the gray and white matter of vertebrates, making this group of animals useful for studies of neurodegenerative events ...
Andressa de Abreu Mello, Carlos Augusto Borges de Andrade Gomes, Rafaela Rocha dos Santos, Cintia Monteiro de Barros, Silvana Allodi   +4 more
wiley   +1 more source

The Role of Sigmar1 in Autophagy Regulation and Disease Therapy. [PDF]

Int J Mol Sci
Ge H, Lin Y, Li J, Zhang R, Xu C.
europepmc   +1 more source

The Function and Trafficking of Atg8 during Autophagosome Formation. [PDF]

Eukaryotic cells rely on autophagy to remove excess or damaged organelles and proteins. In this pathway, cytoplasmic materials are delivered to the lysosomes via double-membrane vesicles, the autophagosomes.
Xie, Zhiping
core  

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

VIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding, Qian Li, Wenjing Yang, Te Liu, Tongtong Tian, Yu Liu, Chunyan Zhang, Baishen Pan, Beili Wang, Fan Wu, Wei Guo   +10 more
wiley   +1 more source

Estrogen Regulates Microtubule-Associated Protein 1 Light Chain 3 in Mouse Uterine Endometrial Epithelium. [PDF]

Dev Reprod
Moon S, Lee S, Choi Y.
europepmc   +1 more source

BCAS-3 is required for the progression of autophagosome formation to degrade paternal mitochondria in <i>Caenorhabditis elegans</i>. [PDF]

iScience
Norizuki T, Sasaki T, Suehiro Y, Mitani S, Kojima W, Yamano K, Matsuda N, Sato M.   +7 more
europepmc   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Cutting edge: ESCRT-mediated phagophore closure in mammals. [PDF]

Biochem J
Takahashi Y, Opozda DM, Wang HG.
europepmc   +1 more source

A comprehensive review of cancer‐induced cardiac wasting

British Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena, Muhammad Shahzeb Khan, Ulrich Keller, Lars Bullinger, Dominik P. Modest, Markus S. Anker   +5 more
wiley   +1 more source