Results 1 to 10 of about 22,892 (257)
Molecular characterization of phagosomes. [PDF]
Journal of Biological Chemistry, 1994 The transformation of newly formed phagosomes into mature phagolysosomes is a process that involves a complex series of interactions between phagosomes and other vacuolar organelles. The machinery required by phagosomes to mediate these interactions is poorly understood.
Desjardins, M. +6 more
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EM Analysis of Phagosomes [PDF]
, 2008 Electron microscopy (EM) is the only technique that can combine sensitive protein-detection methods with detailed information on the substructure of cellular compartments. The purpose of this chapter is to describe some of the methods at the EM level that can be used to analyze the spatial organization of cell organelles with respect to phagosomes or ...
Chantal Chastellier +1 more
openaire +4 more sources
Mechanism of inducible nitric oxide synthase exclusion from mycobacterial phagosomes. [PDF]
PLoS Pathogens, 2007 Mycobacterium tuberculosis is sensitive to nitric oxide generated by inducible nitric oxide synthase (iNOS). Consequently, to ensure its survival in macrophages, M. tuberculosis inhibits iNOS recruitment to its phagosome by an unknown mechanism.
Alexander S Davis +5 more
doaj +2 more sources
Redox-sensitive probes for the measurement of redox chemistries within phagosomes of macrophages and dendritic cells [PDF]
Redox Biology, 2013 There is currently much interest in factors that affect redox chemistries within phagosomes of macrophages and dendritic cells. In addition to the antimicrobial role of reactive oxygen species generation within phagosomes, accumulating evidence suggests ...
Dale R. Balce, Robin M. Yates
doaj +2 more sources
Comparison of the Kinetics of Maturation of Phagosomes Containing Apoptotic Cells and IgG-Opsonized Particles [PDF]
PLoS ONE, 2012 Defective clearance of apoptotic cells has emerged as an important contributing factor to the pathogenesis of many diseases. Although many efforts have been made to understand the machinery involved in the recognition between phagocytes and potential ...
Vieira O
exaly +2 more sources
Maturation of phagosomes containing different erythrophagocytic particles in primary macrophages [PDF]
FEBS Open Bio, 2017 Erythrophagocytosis is a physiological process that aims to remove damaged red blood cells from the circulation in order to avoid hemolysis and uncontrolled liberation of iron. Many efforts have been made to understand heme trafficking inside macrophages,
Inês B. Santarino, Otília V. Vieira
doaj +2 more sources
Phagosomal transport depends strongly on phagosome size [PDF]
Scientific Reports, 2017 AbstractMacrophages internalize pathogens for intracellular degradation. An important part of this process is the phagosomal transport from the cell periphery to the perinuclear region. Biochemical factors are known to influence the fate of phagosomes. Here, we show that the size of phagosomes also has a strong influence on their transport.
Keller, S., Berghoff, K., Kress, H.
openaire +4 more sources
European Journal of Entomology, 2022 In this study, haemocytes present in Papilio hyperbius Linnaeus were identified and characterized. Six different types of haemocyte were recorded in the haemocoel of this species of insect: prohaemocytes, plasmatocytes, granulocytes, spherulocytes ...
Min-Soo GO +6 more
doaj +1 more source
Tuberculosis control by novel vaccines development and Indian initiatives
MGM Journal of Medical Sciences, 2023 Pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is one of the worst microbial diseases of humankind and an awful societal problem, especially in underdeveloped countries.
Prasanta Kumar Ghosh
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, 2023 Mammalian professional phagocytic cells ingest and kill invading microorganisms and prevent the development of bacterial infections. Our understanding of the sequence of events that results in bacterial killing and permeabilization in phagosomes is still
Cosson, Pierre +11 more
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