Results 1 to 10 of about 20,078 (221)

Comparison of the Kinetics of Maturation of Phagosomes Containing Apoptotic Cells and IgG-Opsonized Particles [PDF]

PLoS ONE, 2012
Defective clearance of apoptotic cells has emerged as an important contributing factor to the pathogenesis of many diseases. Although many efforts have been made to understand the machinery involved in the recognition between phagocytes and potential ...
Otilia V Vieira
exaly   +2 more sources

Classification and characterization of immune haemocytes in the larvae of the Indian fritillary, Papilio hyperbius (Lepidopetra: Nymphalidae)

European Journal of Entomology, 2022
In this study, haemocytes present in Papilio hyperbius Linnaeus were identified and characterized. Six different types of haemocyte were recorded in the haemocoel of this species of insect: prohaemocytes, plasmatocytes, granulocytes, spherulocytes ...
Min-Soo GO, Youngwoo CHO, Ki-Byung PARK, Mijeong KIM, Sung Su PARK, Jangwoo PARK, Saeyoull CHO   +6 more
doaj   +1 more source

Tuberculosis control by novel vaccines development and Indian initiatives

MGM Journal of Medical Sciences, 2023
Pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is one of the worst microbial diseases of humankind and an awful societal problem, especially in underdeveloped countries.
Prasanta Kumar Ghosh
doaj   +1 more source

Antimicrobial Activity of Neutrophils Against Mycobacteria

Frontiers in Immunology, 2021
The mycobacterium genus contains a broad range of species, including the human pathogens M. tuberculosis and M. leprae. These bacteria are best known for their residence inside host cells.
Heather A. Parker, Lorna Forrester, Christopher D. Kaldor, Nina Dickerhof, Mark B. Hampton   +4 more
doaj   +1 more source

Cx43-mediated hyphal folding counteracts phagosome integrity loss during fungal infection

Microbiology Spectrum, 2023
Phagolysosomes are crucial organelles during the elimination of pathogens by host cells. The maintenance of their membrane integrity is vital during stressful conditions, such as during Candida albicans infection.
Beatriz Cristovao, Lisa Rodrigues, Steve Catarino, Monica Abreu, Teresa Gonçalves, Neuza Domingues, Henrique Girao   +6 more
doaj   +1 more source

Syntaxin 11 Contributes to the Interferon-Inducible Restriction of Coxiella burnetii Intracellular Infection

mBio, 2023
There is a limited understanding of host defense mechanisms targeting intracellular pathogens that proliferate in a lysosome. Coxiella burnetii is a model bacterial pathogen capable of replicating in the hydrolytic and acidic environment of the lysosome.
Sandhya Ganesan, Natalie N. Alvarez, Samuel Steiner, Karen M. Fowler, Abigail K. Corona, Craig R. Roy   +5 more
doaj   +1 more source

DRAM1 Promotes Lysosomal Delivery of Mycobacterium marinum in Macrophages

Cells, 2023
Damage-Regulated Autophagy Modulator 1 (DRAM1) is an infection-inducible membrane protein, whose function in the immune response is incompletely understood.
Adrianna Banducci-Karp, Jiajun Xie, Sem A. G. Engels, Christos Sarantaris, Patrick van Hage, Monica Varela, Annemarie H. Meijer, Michiel van der Vaart   +7 more
doaj   +1 more source

Metabolism of Gluconeogenic Substrates by an Intracellular Fungal Pathogen Circumvents Nutritional Limitations within Macrophages

mBio, 2020
Microbial pathogens exploit host nutrients to proliferate and cause disease. Intracellular pathogens, particularly those exclusively living in the phagosome such as Histoplasma capsulatum, must adapt and acquire nutrients within the nutrient-limited ...
Qian Shen, Stephanie C. Ray, Heather M. Evans, George S. Deepe, Chad A. Rappleye   +4 more
doaj   +1 more source

Microtubule Motor Transport of Organelles in a Specialized Epithelium: The RPE

Frontiers in Cell and Developmental Biology, 2022
The retinal pigment epithelium (RPE) is a uniquely polarized epithelium that lies adjacent to the photoreceptor cells in the retina, and is essential for photoreceptor function and viability.
Roni A. Hazim, David S. Williams, David S. Williams, David S. Williams, David S. Williams   +4 more
doaj   +1 more source

Impaired Cargo Clearance in the Retinal Pigment Epithelium (RPE) Underlies Irreversible Blinding Diseases

Cells, 2018
Chronic degeneration of the Retinal Pigment Epithelium (RPE) is a precursor to pathological changes in the outer retina. The RPE monolayer, which lies beneath the neuroretina, daily internalises and digests large volumes of spent photoreceptor outer ...
Eloise Keeling, Andrew J. Lotery, David A. Tumbarello, J. Arjuna Ratnayaka   +3 more
doaj   +1 more source