Results 231 to 240 of about 73,321 (302)

Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng   +8 more
wiley   +1 more source

Bone biology in aging periodontal and peri‐implant tissues

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Periodontal disease is an age‐related chronic inflammatory condition leading to tooth loss. Dental implants are an option for replacement of lost teeth in older adults. However, age‐related changes to alveolar bone may have pathological implications for its role in supporting the dentition and dental implants.
Dalia Rasheed Issa   +2 more
wiley   +1 more source

The Human Autophagy Core Complexes. [PDF]

open access: yesAnnu Rev Biochem
Hurley JH.
europepmc   +1 more source

Muscle wasting in cancer cachexia: Mechanisms and the role of exercise

open access: yesExperimental Physiology, EarlyView.
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento   +2 more
wiley   +1 more source

Coupling of cargo to the autophagy receptor is a critical step in ER-phagy. [PDF]

open access: yesSci Adv
Chen S   +7 more
europepmc   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

open access: yesExperimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths   +3 more
wiley   +1 more source

Granulocyte differentiation arrest in HAX1-deficient cells, demonstrated in a new in vitro model of a certain phenotypic aspects of Kostmann disease, is caused by ineffective lipid droplet autophagy and fatty acids uptake. [PDF]

open access: yesCell Death Dis
Wakula M   +15 more
europepmc   +1 more source

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