Results 271 to 280 of about 90,774 (312)

Isopimaric acid derived from Torreya nucifera blocks autophagy and mitophagy to sensitize colon cancer cells to nutrient starvation. [PDF]

Cell Stress Chaperones
Perera RMTD, Kim SL, Kim JH, Kim KC, Lee DS.   +4 more
europepmc   +1 more source

Biomolecular condensation of ERC1 recruits ATG8 and NBR1 to drive autophagosome formation for plant heat tolerance. [PDF]

Proc Natl Acad Sci U S A
Chung KK, Law KC, Zhao Z, Ma J, Zhan XT, Chiang CH, Leung KH, Shrestha R, Wu Y, Li C, Lee KM, Feng L, Li X, Wong KB, Xu SL, Gao C, Zhuang X.   +16 more
europepmc   +1 more source

Dual targeting of the UPS and autophagy as a novel therapy for neurodegenerative proteinopathies. [PDF]

Front Cell Neurosci
Lines G, Helley M, Gillotin S, Brownlees J, Duce J, Smethurst P.   +5 more
europepmc   +1 more source

Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review). [PDF]

Int J Mol Med
Li W, Wang WH, Song Y, Li XJ, Li Y, Wang X, Tian TT, Huang X, Zhao L.   +8 more
europepmc   +1 more source

Correction to “Altered splicing of ATG16‐L1 mediates acquired resistance to tyrosine kinase inhibitors of EGFR by blocking autophagy in non‐small cell lung cancer”

Molecular Oncology, Volume 20, Issue 5, Page 1379-1380, May 2026.
wiley   +1 more source

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Mechanisms governing autophagosome biogenesis

Nature Reviews Molecular Cell Biology, 2020
Autophagosomes are double-membrane vesicles newly formed during autophagy to engulf a wide range of intracellular material and transport this autophagic cargo to lysosomes (or vacuoles in yeasts and plants) for subsequent degradation. Autophagosome biogenesis responds to a plethora of signals and involves unique and dynamic membrane processes ...
Hitoshi Nakatogawa
exaly   +3 more sources

Autophagosome Trafficking

2021
Autophagy is a major intracellular degradation/recycling system that ubiquitously exists in eukaryotic cells. Autophagy contributes to the turnover of cellular components through engulfing portions of the cytoplasm or organelles and delivering them to the lysosomes/vacuole to be degraded.
Jingjing, Ye, Ming, Zheng
openaire   +2 more sources

Autophagosome Biogenesis Machinery

Journal of Molecular Biology, 2020
We review current knowledge of the process of autophagosome formation with special emphasis on the very early steps: turning on the autophagy pathway, assembling the autophagy machinery, and building the autophagosome. The pathway is remarkably well coordinated spatially and temporally, and it shows broad conservation across species and cell types ...
Simon A. Walker, Nicholas T. Ktistakis
openaire   +2 more sources