Results 11 to 20 of about 79,616 (304)

Regulators of autophagosome formation in Drosophila muscles. [PDF]

PLoS Genetics, 2015
Given the diversity of autophagy targets and regulation, it is important to characterize autophagy in various cell types and conditions. We used a primary myocyte cell culture system to assay the role of putative autophagy regulators in the specific ...
Jonathan Zirin, Joppe Nieuwenhuis, Anastasia Samsonova, Rong Tao, Norbert Perrimon   +4 more
doaj   +5 more sources

Fluorescence Microscopy Analysis of Drug Effect on Autophagosome Formation [PDF]

Bio-Protocol, 2014
The autophagy protein, LC3 represents a reliable characteristic marker for autophagosomal structures. The initial LC3 is processed by the cysteine protease autophagy-related gene 4 (Atg4) at its C terminus in order to create LC3-I generally localized in ...
Metodi Stankov, Diana Panayotova-Dimitrova, Martin Leverkus, Georg Behrens   +3 more
doaj   +2 more sources

Does Coxsackievirus B3 Require Autophagosome Formation for Replication? Evidence for an Autophagosome-Independent Mechanism: Insights into Its Limited Potential as a Therapeutic Target [PDF]

Pharmaceuticals
Background/Objectives: Coxsackievirus B3 (CVB3), a neurotropic enterovirus, is a major causative agent of viral encephalitis and myocarditis, yet no protective vaccine or effective antiviral therapy is currently available.
Yun Ji Ga, Jung-Yong Yeh
doaj   +2 more sources

Autophagy-related protein PlATG2 regulates the vegetative growth, sporangial cleavage, autophagosome formation, and pathogenicity of peronophythora litchii [PDF]

Virulence
Autophagy is an intracellular degradation process that is important for the development and pathogenicity of phytopathogenic fungi and for the defence response of plants.
Lin Lv, Chengdong Yang, Xue Zhang, Taixu Chen, Manfei Luo, Ge Yu, Qinghe Chen   +6 more
doaj   +2 more sources

Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation. [PDF]

J Cell Biol, 2023
Broadbent DG, Barnaba C, Perez GI, Schmidt JC.   +3 more
europepmc   +3 more sources

ZDHHC7-mediated <i>S</i>-palmitoylation of ATG16L1 facilitates LC3 lipidation and autophagosome formation. [PDF]

Autophagy
Wei F, Wang Y, Yao J, Mei L, Huang X, Kong H, Chen J, Chen X, Liu L, Wang Z, Wang J, Song J, Kong E, Yang A.   +13 more
europepmc   +3 more sources

Biomolecular condensation of ERC1 recruits ATG8 and NBR1 to drive autophagosome formation for plant heat tolerance. [PDF]

Proc Natl Acad Sci U S A
Chung KK, Law KC, Zhao Z, Ma J, Zhan XT, Chiang CH, Leung KH, Shrestha R, Wu Y, Li C, Lee KM, Feng L, Li X, Wong KB, Xu SL, Gao C, Zhuang X.   +16 more
europepmc   +3 more sources

Metallothionein 3 Potentiates Pulmonary Artery Smooth Muscle Cell Proliferation by Promoting Zinc-MTF1-ATG5 Axis-mediated Autophagosome Formation. [PDF]

Int J Biol Sci
Xiong T, Li Y, Yang M, Huo B, Guo X, Liu L, Huang Y, Zhu X, Hu Q, Wei X, Jiang DS, Yi X.   +11 more
europepmc   +3 more sources

Molecular regulation of autophagosome formation. [PDF]

Biochem Soc Trans, 2022
Macroautophagy, hereafter autophagy, is a degradative process conserved among eukaryotes, which is essential to maintain cellular homeostasis. Defects in autophagy lead to numerous human diseases, including various types of cancer and neurodegenerative disorders.
Hu Y, Reggiori F, Reggiori F.
europepmc   +4 more sources

Transmembrane phospholipid translocation mediated by Atg9 is involved in autophagosome formation. [PDF]

J Cell Biol, 2021
Orii M, Tsuji T, Ogasawara Y, Fujimoto T.   +3 more
europepmc   +3 more sources