Results 21 to 30 of about 79,616 (304)

Multilayered regulation of autophagy by the Atg1 kinase orchestrates spatial and temporal control of autophagosome formation. [PDF]

Mol Cell, 2021
Schreiber A, Collins BC, Davis C, Enchev RI, Sedra A, D'Antuono R, Aebersold R, Peter M.   +7 more
europepmc   +2 more sources

SIGMAR1/Sigma-1 receptor: a key regulator in stabilizing and translating <i>LC3B</i> mRNA for autophagosome formation. [PDF]

Autophagy
Chen YJ, Knupp J, Wang E, Arvan P, Tsai B.   +4 more
europepmc   +3 more sources

Erratum: Assessing Autophagy in Microglia: A Two-Step Model to Determine Autophagosome Formation, Degradation, and Net Turnover [PDF]

Frontiers in Immunology, 2021
Frontiers Production Office
doaj   +2 more sources

Membrane closure in stress induced-autophagosome formation [PDF]

Cell Stress, 2018
Eiji Morita
doaj   +3 more sources

Autophagosome formation: not necessarily an inside job [PDF]

Cell Research, 2010
Andrea Longatti, Andrea Orsi, Sharon A. Tooze   +2 more
openalex   +3 more sources

Dynamics of Autophagosome Formation [PDF]

Plant Physiology, 2017
Environmental stress activates autophagy and leads to autophagosome formation at the endoplasmic reticulum.
Junmarie Soto-Burgos, Xiaohong Zhuang, Liwen Jiang, Diane C. Bassham   +3 more
openaire   +3 more sources

Autophagosome Formation: Tracing the Source [PDF]

Developmental Cell, 2013
Although it is well appreciated that autophagy begins with phagophore formation and expansion through lipid acquisition to become the autophagosome, this process remains poorly understood, with the source of autophagosome membrane controversial. Reporting recently in Nature, Hamasaki et al.
Bernard, Amélie, Klionsky, Daniel J.
openaire   +2 more sources

Autophagy adaptor protein p62/SQSTM1 and autophagy-related gene Atg5 mediate autophagosome formation in response to Mycobacterium tuberculosis infection in dendritic cells. [PDF]

PLoS ONE, 2013
Mycobacterium tuberculosis is an intracellular pathogen that can survive within phagocytic cells by inhibiting phagolysosome biogenesis. However, host cells can control the intracellular M. tuberculosis burden by the induction of autophagy. The mechanism
Shintaro Seto, Kunio Tsujimura, Toshinobu Horii, Yukio Koide   +3 more
doaj   +1 more source

Short and long sleeping mutants reveal links between sleep and macroautophagy

eLife, 2021
Sleep is a conserved and essential behavior, but its mechanistic and functional underpinnings remain poorly defined. Through unbiased genetic screening in Drosophila, we discovered a novel short-sleep mutant we named argus.
Joseph L Bedont, Hirofumi Toda, Mi Shi, Christine H Park, Christine Quake, Carly Stein, Anna Kolesnik, Amita Sehgal   +7 more
doaj   +1 more source

STING recruits WIPI2 for autophagosome formation. [PDF]

Autophagy, 2023
Induction of autophagy is a primordial function of the cGAS-STING pathway. However, the molecular mechanisms regulating autophagosome formation during STING-induced autophagy remain largely unknown. Recently, we reported that STING directly interacts with WIPI2 to recruit WIPI2 onto STING-positive vesicles for LC3 lipidation and autophagosome formation.
Wan W, Liu W.
europepmc   +3 more sources