Results 101 to 110 of about 58,150 (299)
Wildtype yeast autophagosomes (replicate 1)
, 2012 Individual autophagosomes from untreated wildtype yeast cells at steady state. These images are supplementary data for my lab's PLoS ONE paper, which is linked below. Similar data from my lab is available for viewing on The Cell: An Image Library,
Ethan Perlstein (97610) +1 more
core +1 more source
NLSS3 Impairs SHM1 Autophagic Degradation to Regulate Leaf Morphology and Salt Tolerance in Rice
Advanced Science, EarlyView.In rice, NLSS3 binds and shields SHM1 from autophagic degradation to maintain serine homeostasis. The A132P mutation in nlss3 disrupts this, triggering SHM1 loss, metabolic dysfunction, K+ imbalance, and impaired ROS scavenging, which collectively drive narrow leaves and salt sensitivity.
Xiong Liu +15 more
wiley +1 more source
The autophagosome is overrated! [PDF]
Autophagy, 2011 For some people, the appearance of autophagosomes by electron microscopy is the “gold standard” for demonstrating macroautophagy. I could quibble with this idea for various technical reasons. For example, just how many autophagosomes are needed per cell to truly indicate an increase in autophagy, and how often do people carry out morphometric analyses ...
openaire +2 more sources
Advanced Science, EarlyView.PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin +11 more
wiley +1 more source
Journal of VirologyGrass carp reovirus (GCRV) is the most virulent pathogen within the genus Aquareovirus, belonging to the family Spinareoviridae. GCRV is categorized into three genotypes, with type II (GCRV-II) being the predominant strain circulating in China ...
Qian Wang +9 more
doaj +1 more source
Maturation of autophagosomes and endosomes: A key role for Rab7
, 2013 Macroautophagy is an important route in cellular maintenance, in the breakdown and reuse of intracellular materials. It is closely related to endocytosis, the means by which the cell can absorb extracellular material, as both macroautophagy and ...
Hyttinen, Juha M.T. +3 more
core +1 more source
Advanced Science, EarlyView.HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang +10 more
wiley +1 more source
PG increases the formation of autophagosomes and lysosomes.
, 2019 HepJ5 cells were exposed to 80 μg/ml PG for specific times. Autophagosome and lysosomes were detected using specific dyes and detected by NC-3000. (A) The formation of autophagosomes was increased after PG treatment in HepJ5 and Mahlavu cells compared ...
Yu-Jia Chang (143398) +2 more
core +1 more source
Advanced Science, EarlyView.SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao +15 more
wiley +1 more source
miR-155-induced autophagy promotes the formation of mycobacterial autophagosomes.
, 2013 (A) RAW264.7 cells stably expressing GFP-LC3 were transiently transfected with control or miR-155 mimic and then infected with Texas Red-labeled BCG for 1 h. The co-localization of BCG with LC3 was detected by confocal microscopy.
Qiu Zhong (331741) +12 more
core +1 more source