Expression of IMD-CBM peptide induces the autophagic degradation of CAV1 (caveolin 1) to inhibit LDL transcytosis and retard diabetic atherosclerosis. [PDF]
Wang L +9 more
europepmc +1 more source
ABSTRACT Oncogenic condensates act as biophysical sanctuaries that stabilize malignant survival programs. However, a universal regulator capable of orchestrating the integrated biophysical axes governing cellular phase behavior has remained elusive.
Doris Loh +3 more
wiley +1 more source
The Role of Autophagy-Lysosomal Pathways in Photoreceptor Death in the rd10 Mouse Model of Inherited Retinal Degeneration. [PDF]
Vessey KA +7 more
europepmc +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The VaATG6-VaBI-1 module coordinates ER-associated autophagy and ROS homeostasis for cold tolerance in grapevine. [PDF]
Zheng Q +5 more
europepmc +1 more source
The role of autophagy in microwave radiation induced toxicity in iPSC-derived cardiomyocytes. [PDF]
Zhang C +6 more
europepmc +1 more source
Inhibition of SGK1 Alleviates Apoptosis and Oxidative Stress in Dry Eye Disease by Activating FoxO3a-Mediated Autophagy. [PDF]
Tang Y +7 more
europepmc +1 more source
The Fragile Balance: Autophagy's Role in Neurodegenerative Disease Progression. [PDF]
Bhushan B +5 more
europepmc +1 more source
FGF21-Mediated Upregulation of SIRT1 Delays Intervertebral Disc Degeneration by Promoting PINK1/Parkin Dependent Mitophagy Through Deacetylation of FOXO3. [PDF]
Wu ZL +7 more
europepmc +1 more source

