Results 261 to 270 of about 72,795 (291)

Role of Autophagy Induced by Pmel17 in the Pathogenesis of Vitiligo. [PDF]

J Inflamm Res
Sun L, Sun J, Feng Y, Zhu L, Li H, Xu C, Guo C.   +6 more
europepmc   +1 more source

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

Advanced Science, Volume 13, Issue 8, 9 February 2026.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang, Ran Yan, Lede Lin, Lei Xiang, Xiaozhi Xia, Liao Peng, Xiaoshuai Gao, Jiawei Chen, Yang Xiong, Liang Zhou, Yunfeng Lin   +10 more
wiley   +1 more source

Zika virus impairs autophagic flux in trabecular meshwork, and inhibition of autophagy restricts ocular viral transmission and associated pathology. [PDF]

Microbiol Spectr
Ahmad F, Kumar P, Singh P, Joshi T, Singh PK.   +4 more
europepmc   +1 more source

Sex‐specific acceleration of Alzheimer's pathogenesis by chronic sleep‐deprivation

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sleep impairments likely contribute to Alzheimer's pathology, though specific contributions to disease progression are incompletely understood. We propose that autophagic impairment is associated with chronic sleep disruption and examine how sleep loss and stress influence disease development, including having impacts on ...
Darcy Wear, Christopher Daniel Morrone, Dominic Simpson, Fang Liu, Syed Abid Hussaini, Wai Haung Yu   +5 more
wiley   +1 more source

Developing Endogenous Autophagy Reporters in <i>Caenorhabditis elegans</i> to Monitor Basal and Starvation-Induced Autophagy. [PDF]

Int J Mol Sci
Bördén K, Vellai T, Sigmond T.
europepmc   +1 more source

Insufficient Expression of the Autophagic Protein ATG16L1 Results in Accelerated Carcinogenesis Related to an Aberrant B Cell Response

Cancer Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Autophagy‐related proteins (ATGs) regulate a great variety of cellular responses beyond autophagy. In cancer, the role of ATG proteins is central, as evidenced in spontaneous cancer emerging in animals lacking ATG proteins. Aim To determine whether ATG16L1 may be participating in tumorigenesis in colonic and oral mucosa and its ...
Daniela Mendiola, Betsaida Ortiz, Oscar Nieto, Marisol I. González, Danielle Vannan, Bertus Eksteen, Alejandro Martínez, Diego Mateos, Mónica G. Mendoza‐Rodríguez, Miriam Rodríguez‐Sosa, Luis I. Terrazas, José L. Reyes   +11 more
wiley   +1 more source

Clathrin-coated vesicles are targeted for selective autophagy during osmotic stress

Dragwidge JM, Buridan M, Kraus J, Kosuth T, Chambaud C, Brocard L, Yperman K, Mylle E, Vandorpe M, Eeckhout D, De Jaeger G, Pleskot R, Bernard A, Van Damme D.   +13 more
europepmc   +1 more source

Autophagy in the Pathogenesis of Membranous Nephropathy. [PDF]

Kidney Med
Ponticelli C, Reggiani F, Moroni G.
europepmc   +1 more source

NCOA7 inhibits renal cancer progression by inducing autophagy and lipid metabolism through V-ATPase interaction. [PDF]

Cell Death Discov
Wang J, Luo H, He Q, Shao H, Cai X, Cao Y, Wang Y, Wang D.   +7 more
europepmc   +1 more source