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Autophagy and autophagy-related pathways in cancer [PDF]
Nature Reviews Molecular Cell Biology, 2023 Maintenance of protein homeostasis and organelle integrity and function is critical for cellular homeostasis and cell viability. Autophagy is the principal mechanism that mediates the delivery of various cellular cargoes to lysosomes for degradation and ..., Kevin M Ryanexaly +6 more sourcesAutophagy in immunity and inflammation
Nature, 2011 Autophagy is an essential, homeostatic process by which cells break down their own components. Perhaps the most primordial function of this lysosomal degradation pathway is adaptation to nutrient deprivation.Beth Levine, Mizushima Noboru, Herbert W Virgin +2 moreexaly +2 more sourcesGuidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy, 2021 In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field.D. Klionsky, A. K. Abdel-Aziz, Sara Abdelfatah, M. Abdellatif, A. Abdoli, S. Abel, H. Abeliovich, Marie H Abildgaard, Y. P. Abudu, A. Acevedo-Arozena, I. Adamopoulos, K. Adeli, T. Adolph, A. Adornetto, E. Aflaki, G. Agam, A. Agarwal, B. Aggarwal, M. Agnello, P. Agostinis, J. Agrewala, A. Agrotis, P. Aguilar, S. T. Ahmad, Zubair M. Ahmed, Ulises Ahumada-Castro, S. Aits, S. Aizawa, Yunus Akkoç, Tonia Akoumianaki, Hafize Aysin Akpinar, A. M. Al-Abd, Lina Al-Akra, A. Al-Gharaibeh, M. Alaoui-Jamali, S. Alberti, E. Alcocer-Gómez, C. Alessandri, M. Ali, M. Alim Al-Bari, S. Aliwaini, Javad Alizadeh, Eugènia Almacellas, A. Almasan, A. Alonso, G. Alonso, N. Altan-Bonnet, D. Altieri, Elida M. C. Álvarez, S. Alves, C. Alves da Costa, Mazen M. Alzaharna, M. Amadio, C. Amantini, C. Amaral, Susanna Ambrosio, A. Amer, Veena Ammanathan, Zhenyi An, S. Andersen, S. Andrabi, Magaiver Andrade-Silva, Allen M. Andres, S. Angelini, D. Ann, Uche C. Anozie, M. Ansari, Pedro Antas, Adam Antebi, Zuriñe Antón, Tahira Anwar, L. Apetoh, N. Apostolova, T. Araki, Y. Araki, Kohei Arasaki, W. Araújo, J. Araya, C. Arden, M. Arevalo, Sandro Arguelles, E. Arias, J. Arikkath, H. Arimoto, Aileen R. Ariosa, D. Armstrong-James, Laetitia Arnauné-Pelloquin, Á. Aroca, D. Arroyo, I. Arsov, R. Artero, D. Asaro, M. Aschner, M. Ashrafizadeh, O. Ashur-Fabian, A. Atanasov, Alicia K. Au, P. Auberger, H. Auner, L. Aurelian, R. Autelli, L. Avagliano, Y. Ávalos, Sanja Aveic, C. Aveleira, Tamar Avin-Wittenberg, Yucel Aydin, S. Ayton, S. Ayyadevara, M. Azzopardi, M. Baba, J. Backer, Steven K. Backues, D. Bae, O. Bae, S. Bae, E. Baehrecke, Ahruem Baek, Seung-Hoon Baek, S. H. Baek, G. Bagetta, A. Bagniewska-Zadworna, Hua Bai, J. Bai, X. Bai, Yidong Bai, N. Bairagi, Shounak Baksi, T. Balbi, C. Baldari, W. Balduini, A. Ballabio, M. Ballester, S. Balazadeh, R. Balzan, R. Bandopadhyay, Sreeparna Banerjee, Sulagna Banerjee, Agnes Banreti, Yan Bao, M. Baptista, A. Baracca, C. Barbati, A. Bargiela, D. Barilà, Peter G. Barlow, S. Barmada, E. Barreiro, G. Barreto, J. Bartek, B. Bartel, Alberto Bartolomé, Gaurav Barve, S. Basagoudanavar, D. Bassham, R. Bast, A. Basu, H. Batoko, Isabella Batten, E. Baulieu, B. L. Baumgarner, J. Bayry, R. Beale, I. Beau, F. Beaumatin, Luiz R G Bechara, G. Beck, M. Beers, J. Begun, C. Behrends, G. Behrens, R. Bei, Eloy Bejarano, Shai Bel, C. Behl, Amine Belaid, Naïma Belgareh-Touzé, C. Bellarosa, F. Belleudi, Melissa Belló Pérez, R. Bello-Morales, J. O. Beltran, S. Beltrán, D. Benbrook, Mykolas Bendorius, B. Benitez, Irene Benito-Cuesta, Julien Bensalem, M. Berchtold, S. Berezowska, D. Bergamaschi, M. Bergami, A. Bergmann, L. Berliocchi, C. Berlioz-Torrent, Amélie Bernard, L. Berthoux, C. Besirli, Sébastien Besteiro, V. Betin, R. Beyaert, Jelena S. Bezbradica, Kiran Bhaskar, I. Bhatia-Kiššová, Resham Bhattacharya, S. Bhattacharya, S. Bhattacharyya, M. Bhuiyan, S. Bhutia, Lanrong Bi, X. Bi, T. J. Biden, K. Bijian, Viktor A. Billes, N. Binart, C. Bincoletto, Å. Birgisdottir, G. Bjørkøy, G. Blanco, A. Blas-García, J. Błasiak, Robert Blomgran, K. Blomgren, J. Blum, Emilio Boada-Romero, Mirta Boban, K. Boesze-Battaglia, Philippe Boeuf, B. Boland, P. Bomont, P. Bonaldo, S. Bonam, L. Bonfili, J. Bonifacino, B. Boone, M. Bootman, M. Bordi, C. Borner, B. Bornhauser, G. Borthakur, J. Bosch, S. Bose, L. Botana, J. Botas, C. Boulanger, M. Boulton, M. Bourdenx, Benjamin Bourgeois, Nollaig M. Bourke, G. Bousquet, P. Boya, P. Bozhkov, L. Bozi, T. Bozkurt, D. Brackney, C. Brandts, R. Braun, G. Braus, R. Bravo-Sagua, J. M. Bravo-San Pedro, P. Brest, M. Bringer, Alfredo Briones-Herrera, V. Broaddus, P. Brodersen, J. Brodsky, S. Brody, P. Bronson, J. Bronstein, C. N. Brown, Rhoderick E. Brown, P. Brum, J. Brumell, N. Brunetti‐Pierri, D. Bruno, R. Bryson-Richardson, C. Bucci, C. Buchrieser, M. Bueno, L. E. Buitrago‐Molina, Simone Buraschi, S. Buch, J. Buchan, E. Buckingham, H. Budak, M. Budini, G. Bultynck, F. Burada, J. Burgoyne, M. Burón, Victor H. Bustos, S. Büttner, Elena Butturini, Aaron Byrd, I. Cabas, Sandra Cabrera-Benitez, K. Cadwell, Jingjing Cai, L. Cai, Qian Cai, M. Cairó, J. Calbet, G. Caldwell, Kim A. Caldwell, J. Call, R. Calvani, A. Calvo, Miguel Calvo-Rubio Barrera, N. O. Câmara, J. Camonis, N. Camougrand, M. Campanella, E. Campbell, François-Xavier Campbell-Valois, S. Campello, I. Campesi, Juliane C Campos, O. Camuzard, J. Cancino, Danilo Candido de Almeida, L. Canesi, I. Caniggia, B. Canonico, C. Cantí, Bin Cao, M. Caraglia, B. Caramés, E. Carchman, E. Cardenal-Muñoz, C. Cárdenas, L. Cárdenas, S. Cardoso, J. Carew, G. Carle, G. Carleton, S. Carloni, D. Carmona‐Gutierrez, L. Carneiro, O. Carnevali, Julian M. Carosi, Serena Carra, A. Carrier, L. Carrier, Bernadette Carroll, A. Carter, A. N. Carvalho, M. Casanova, Caty Casas, J. Casas, Chiara Cassioli, Eliseo F. Castillo, Karen Castillo, Sonia Castillo-Lluva, F. Castoldi, M. Castori, A. F. Castro, M. Castro-Caldas, J. Castro-Hernandez, S. Castro-Obregón, S. Catz, C. Cavadas, F. Cavaliere, G. Cavallini, M. Cavinato, M. Cayuela, Paula Cebollada Rica, V. Cecarini, F. Cecconi, M. Cechowska-Pasko, S. Cenci, V. Ceperuelo-Mallafré, J. Cerqueira, J. Cerutti, D. Cervia, V. Cetintas, S. Cetrullo, H. Chae, A. Chagin, C. Chai, Gopal Chakrabarti, Oishee Chakrabarti, T. Chakraborty, T. Chakraborty, Mounia Chami, Georgios Chamilos, D. Chan, Edmond Y. W. Chan, E. Chan, H. Chan, H. H. Chan, H. Chan, M. Chan, Y. Chan, Partha K. Chandra, Chih-Peng Chang, Chunmei Chang, Hao-Chun Chang, K. Chang, J. Chao, T. Chapman, N. Charlet-Berguerand, S. Chatterjee, S. K. Chaube, A. Chaudhary, S. Chauhan, E. Chaum, F. Checler, M. Cheetham, Chang-Shi Chen, Guang-Chao Chen, Jian-Fu Chen, Liam Chen, Leilei Chen, Lin Chen, Mingliang Chen, Mu-Kuan Chen, Ning Chen, Quan Chen, Ruey-Hwa Chen, Shi Chen, Wei Chen, Weiqiang Chen, Xinming Chen, Xiong-Wen Chen, Xu Chen, Yan Chen, Ye-Guang Chen, Yingyu Chen, Yongqiang Chen, Yu-Jen Chen, Yue‐Qin Chen, Z. Chen, Zhi Chen, Zhihua Chen, Zhijian J. Chen, Zhixiang Chen, Hanhua Cheng, Jun Cheng, Shi-Yuan Cheng, W. Cheng, Xiaodong Cheng, Xiu-Tang Cheng, Yiyun Cheng, Zhiyong Cheng, Zhong Chen, H. Cheong, J. K. Cheong, B. Chernyak, S. Cherry, C. Cheung, C. Cheung, K. Cheung, É. Chevet, Richard J. Chi, A. Chiang, F. Chiaradonna, R. Chiarelli, M. Chiariello, Nathalia Chica, S. Chiocca, M. Chiong, S. Chiou, Abhilash I. Chiramel, V. Chiurchiù, D. Cho, Seong-Kyu Choe, A. Choi, Mary E. Choi, Kamalika Roy Choudhury, Norman S. Chow, C. Chu, Jason P. Chua, J. J. Chua, Hyewon Chung, Kin Pan Chung, Seockhoon Chung, So-Hyang Chung, Yuen-Li Chung, V. Cianfanelli, I. Ciechomska, M. Cifuentes, Laura Cinque, S. Çırak, M. Cirone, M. J. Clague, R. Clarke, E. Clementi, E. Coccia, P. Codogno, E. Cohen, Mickael M. Cohen, T. Colasanti, Fiorella Colasuonno, R. Colbert, A. Colell, M. Čolić, N. Coll, M. Collins, M. Colombo, Daniel A. Colón-Ramos +499 moresemanticscholar +1 more sourceEndoplasmic Reticulum Stress in Systemic Lupus Erythematosus and Lupus Nephritis: Potential Therapeutic Target
Journal of Immunology Research, 2023 Systemic lupus erythematosus (SLE) is a complex autoimmune disease. Approximately one-third to two-thirds of the patients with SLE progress to lupus nephritis (LN). The pathogenesis of SLE and LN has not yet been fully elucidated, and effective treatment Hui-Yuan Li, Li-Feng Huang, Xiao-Rong Huang, Dan Wu, Xiao-Cui Chen, Ji-Xin Tang, Ning An, Hua-Feng Liu, Chen Yang +8 moredoaj +1 more sourcehUC-MSC transplantation therapy effects on lupus-prone MRL/lpr mice at early disease stages
Stem Cell Research & Therapy, 2023 Background The efficacy of human umbilical cord mesenchymal stem cell (hUC-MSC) transplantation in treating systemic lupus erythematosus (SLE) has been confirmed by small-scale clinical trials.Fengbiao Guo, Quanren Pan, Ting Chen, Shuzhen Liao, Shangmei Li, Aifen Li, Shuxian Chen, Jiaxuan Chen, Zengzhi Xiao, Hongyong Su, Lawei Yang, Chen Yang, Hua-feng Liu, Qingjun Pan +13 moredoaj +1 more sourceUrsolic Acid Impairs Cellular Lipid Homeostasis and Lysosomal Membrane Integrity in Breast Carcinoma Cells
Cells, 2022 Cancer is one of the leading causes of death worldwide, thus the search for new cancer therapies is of utmost importance. Ursolic acid is a naturally occurring pentacyclic triterpene with a wide range of pharmacological activities including anti ...Ditte L. Fogde, Cristina P. R. Xavier, Kristina Balnytė, Lya K. K. Holland, Kamilla Stahl-Meyer, Christoffel Dinant, Elisabeth Corcelle-Termeau, Cristina Pereira-Wilson, Kenji Maeda, Marja Jäättelä +9 moredoaj +1 more source
