Results 51 to 60 of about 286,383 (199)

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

open access: yesAdvanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui   +5 more
wiley   +1 more source

Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration

open access: yesAdvanced Therapeutics, EarlyView.
Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana   +5 more
wiley   +1 more source

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

open access: yesAdvanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang   +14 more
wiley   +1 more source

Role of cAMP in the Regulation of Hepatocytic Autophagy [PDF]

open access: bronze, 1996
Ingunn Holen   +3 more
openalex   +1 more source

Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis

open access: yesAdvanced Science, EarlyView.
An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Zhihua Ou   +35 more
wiley   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

Huntingtin Expression Stimulates Endosomal–Lysosomal Activity, Endosome Tubulation, and Autophagy [PDF]

open access: bronze, 2000
Kimberly B. Kegel   +6 more
openalex   +1 more source

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