Results 91 to 100 of about 193,799 (312)

Kinin-B1 receptors in ischaemia-induced pancreatitis: Functional importance and cellular localisation [PDF]

, 2003
In this study we compare the role of kininB1 and B2 receptors during ischaemia/reperfusion of rat pancreas. Our investigations were prompted by the observation that infusion of a kininB2 receptor antagonist produced significant improvement in acute ...
Ahluwalia A., Bassi D., Bhoola K.D., Bloechle C., Dendorfer A., Griesbacher T., Hall J.M., Klar E., Pruneau D., Regoli D.   +9 more
core   +1 more source

Natural variation in PtobZIP18 confers the trade‐off between stem growth and drought tolerance in Populus

Plant Biotechnology Journal, EarlyView.
Summary Maintaining the balance between growth and drought tolerance is arguably one of the most prevalent challenges encountered by woody plants. In this study, we performed genome‐wide association studies (GWAS) of percentage loss of diameter (PLD) in the stems of 300 Populus tomentosa accessions under drought stress. Our analysis identified the bZIP
Zhuoying Jin, Peng Li, Rui Huang, Lianzheng Li, Mengjiao Zhang, Donghai Zhang, Mingjia Yuan, Jintao Du, Jiaxuan Zhou, Wenke Zhang, Liang Du, Li Ji, Mingyang Quan, Deqiang Zhang, Li‐Jun Liu, Qingzhang Du   +15 more
wiley   +1 more source

Porcine intestinal glycosphingolipids recognized by F6-fimbriated enterotoxigenic Escherichia coli [PDF]

, 2014
One important virulence factor of enterotoxigenic Escherichia coli is their ability to adhere via fimbrial adhesins to specific receptors located on the intestinal mucosa. Here, the potential glycosphingolipid receptors of enterotoxigenic F6-fimbriated E.
Benktander, John, Coddens, Annelies, Cox, Eric, Johansson, Miralda Madar, Teneberg, Susann   +4 more
core   +2 more sources

Matrix metalloproteinase inhibition protects against junctophilin‐2 proteolysis during doxorubicin‐induced cardiotoxicity

British Journal of Pharmacology, Volume 182, Issue 17, Page 4103-4121, September 2025.
Abstract Background and Purpose Treatment of cancer patients with anthracyclines is known to cause dose‐dependent cardiotoxicity through several mechanisms including enhanced oxidative stress, ultimately resulting in defective excitation–contraction coupling.
Wesam Bassiouni, Brandon Y. H. Chan, Andrej Roczkowsky, Joshua W. Kranrod, Zabed Mahmud, Joseph O. Primeau, Woo Jung Cho, Howard S. Young, John M. Seubert, Richard Schulz   +9 more
wiley   +1 more source

Quantitative autoradiography of multiple 5-HT1 receptor subtypes in the brain of control or 5,7-dihydroxytryptamine-treated rats

Journal of Neuroscience, 1986
The distribution of the 2 main types (A and B) of 5-HT1 binding sites in the rat brain was studied by light-microscopic quantitative autoradiography. The 5-HT1A sites were identified using 3H-8-hydroxy-2- (N-dipropylamino)tetralin (3H-8-OH-DPAT) or 3H-5 ...
D. Vergé, G. Daval, M. Marcinkiewicz, A. Patey, S. Mestikawy, H. Gozlan, M. Hamon   +6 more
semanticscholar   +1 more source

Actinide bioimaging in tissues: Comparison of emulsion and solid track autoradiography techniques with the iQID camera. [PDF]

PLoS ONE, 2017
This work presents a comparison of three autoradiography techniques for imaging biological samples contaminated with actinides: emulsion-based, plastic-based autoradiography and a quantitative digital technique, the iQID camera, based on the numerical ...
Stephanie Lamart, Brian W Miller, Anne Van der Meeren, Anissa Tazrart, Jaime F Angulo, Nina M Griffiths   +5 more
doaj   +1 more source

Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) magnetic resonance metabolic imaging identifies the penumbra following acute ischemic stroke [PDF]

, 2018
The ability to identify metabolically active and potentially salvageable ischaemic penumbra is crucial for improving treatment decisions in acute stroke patients.
Brennan, David, Deuchar, Graeme A., Holmes, William M., Macrae, I. Mhairi, Santosh, Celestine, Shaw, Martin   +5 more
core   +1 more source

Novel 4,5‐Dihydrothiazole‐Phenylpiperazine Derivatives: Synthesis, Docking Studies and Pharmacological Evaluation as Serotonergic Agents

ChemMedChem, Volume 20, Issue 15, August 2, 2025.
The synthesis of a new series of 4,5‐dihydrothiazol‐2‐ylphenylpiperazine derivatives as serotoninergic ligands is described and tested for their affinity toward 5‐HT1A, 5‐HT2A,and 5‐HT2C and selected for further in vivo assays to determine their functional activity. The pharmacological studies highlight that among the developed derivatives, FG‐7 and FG‐
Giorgia Andreozzi, Natalia Karkoszka, Rosa Sparaco, Angela Corvino, Beatrice Severino, Vincenzo Santagada, Elisa Magli, Ewa Gibuła‐Tarłowska, Jolanta H. Kotlińska, Kinga Gawel, Raffaele Capasso, Anna Lesniak, Nataliia Semenko, Agnieszka A. Kaczor, Anna Bielenica, Grażyna Biała, Giuseppe Caliendo, Ewa Kędzierska, Ferdinando Fiorino   +18 more
wiley   +1 more source

Early life stress and hormonal status influence orexin‐1 receptor expression in structures regulating cardiorespiratory responses to CO2

Experimental Physiology, Volume 110, Issue 8, Page 1138-1153, 1 August 2025.
Abstract Excessive cardiorespiratory responses to CO2 are a hallmark of panic disorder (PD). Female sex and exposure to early life stress are risk factors for PD. Neonatal maternal separation (NMS; 3 h/day, postnatal days 3–12) augments the ventilatory response to CO2 by ∼35% relative to controls; this effect is most notable during pro‐oestrus but is ...
Stéphanie Fournier, Julie Plamondon, Denis Richard, Richard Kinkead   +3 more
wiley   +1 more source

A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice [PDF]

, 2010
BACKGROUND: Parkinson's disease (PD), the second most frequent neurodegenerative disorder at old age, can be caused by elevated expression or the A53T missense mutation of the presynaptic protein alpha-synuclein (SNCA). PD is characterized pathologically
Auburger, Georg, Bockhart, Vanessa, Bonin, Michael, Calabresi, Paolo, Double, Kay L., Fernández-Ruiz, Javier, García-Arencibia, Moisés, Gerlach, Manfred, Gispert, Suzana, Kurz, Alexander, Lastres-Becker, Isabel, Liss, Birgit, Lüddens, Hartmut, Nuber, Silke, Schlaudraff, Falk, Tantucci, Michela, Tozzi, Alessandro, Wüllner, Ullrich   +17 more
core   +1 more source