Results 31 to 40 of about 161,099 (207)

Holliday junction resolvase in Schizosaccharomyces pombe has identical endonuclease activity to the CCE1 homologue YDC2 [PDF]

, 1998
A novel Holliday junction resolving activity has been identified in fractionated cell extracts of the fission yeast Schizosaccharomyces pombe . The enzyme catalyses endonucleolytic cleavage of Holliday junction-containing chi DNA and synthetic four-way ...
Keeley, A, Oram, M, Tsaneva, IR
core   +2 more sources

In Vitro and In Vivo Characterization of Selected Fluorine-18 Labeled Radioligands for PET Imaging of the Dopamine D3 Receptor

Molecules, 2016
Cerebral dopamine D3 receptors seem to play a key role in the control of drug-seeking behavior. The imaging of their regional density with positron emission tomography (PET) could thus help in the exploration of the molecular basis of drug addiction.
Natascha Nebel, Simone Maschauer, Torsten Kuwert, Carsten Hocke, Olaf Prante   +4 more
doaj   +1 more source

Alterations in Cerebral Blood Flow and Glucose Utilization in Mice Overexpressing the Amyloid Precursor Protein

Neurobiology of Disease, 2002
We have used quantitative autoradiographic techniques to study the relationship between cerebral blood flow (CBF) and glucose utilization (CGU) in two lines of transgenic mice overexpressing Swedish mutant amyloid precursor protein (APP) and APP-derived ...
Kiyoshi Niwa, Ken Kazama, Steven G. Younkin, George A. Carlson, Costantino Iadecola   +4 more
doaj   +1 more source

Biosynthesis of Mitochondrial Porin and Insertion into the Outer Mitochondrial Membrane of Neuruspora crassa [PDF]

, 1982
Mitochondrial porin, the major protein of the outer mitochondrial membrane is synthesized by free cytoplasmic polysomes. The apparent molecular weight of the porin synthesized in homologous or heterologous cell-free systems is the same as that of the ...
Cassady W. E., Colombini M., Conboy J. G., Cote C., Cowlesmith I., Freitag H., Glizin V., Hallermayer R., Hennig B., Korb H., Lewin A., Maccecchini M. L., Maccechini M. L., Matsuura S., Mihara K., Nabi N., Nelson N., Neupert W., Oda T., Palmiter R. D., Payvar F., Raymond Y., Scheele G., Schleyer M., Schmelzer E., Sebald W., Sherton C. C., Shore G. C., Sonderegger P., Teintze M., Ullrich A., Zelman L. S., Zimmermann R., Zimmermann R., Zimmermann R., Zimmermann R.   +35 more
core   +1 more source

Decreased MK-801 Binding in Discrete Hippocampal Regions of Prion-Infected Mice

Neurobiology of Disease, 2001
The neurochemical alterations associated with neurodegeneration in prion diseases are not well defined. It is therefore of interest to study the influence of prion infection on messenger molecules and their receptors.
M. Diez, S.J. DeArmond, D. Groth, S.B. Prusiner, T. Hökfelt   +4 more
doaj   +1 more source

Analysis of capecitabine metabolites in conjunction with digital autoradiography in a murine model of pancreatic cancer suggests extensive drug penetration through the tumor

Pharmacology Research & Perspectives, 2022
Previously published digital autoradiography of 3H‐labeled capecitabine reveals a near‐uniform distribution of activity throughout a murine pancreatic model.
James Russell, Louise Fanchon, Hanan Alwaseem, Henrik Molina, Isabella O’Donoghue, Amber Bahr, Elisa deStanchina, Nagavarakishore Pillarsetty, John L. Humm   +8 more
doaj   +1 more source

Noninvasive PET Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering [PDF]

, 2016
Transplantation of human muscle precursor cells (hMPCs) is envisioned for the treatment of various muscle diseases. However, a feasible noninvasive tool to monitor cell survival, migration, and integration into the host tissue is still missing. METHODS:
Ametamey, Simon M., Betzel, Thomas, Dinulovic, Ivana, Eberli, Daniel, Handschin, Christoph, Haralampieva, Deana, Krämer, Stefanie D., Salemi, Souzan, Schibli, Roger, Stoelting, Meline, Sulser, Tullio   +10 more
core   +2 more sources

Scientific Opinion on Flavouring Group Evaluation 302 (FGE.302): N-(2-methylcyclohexyl)-2,3,4,5,6-pentafluoro-benzamide from Chemical Group 30 [PDF]

, 2017
Publisher ...
Anastassiadou, Maria, Bolognesi, Claudia, Brimer, Leon, Castle, Laurence, Cravedi, Jean-Pierre, de Fátima Tavares Poças, Maria, EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Engel, Karl-Heinz, Fowler, Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kärenlampi, Sirpa, Mennes, Wim, Mulder, Gerard, Penninks, André, Rosaria Milana, Maria, Silano, Vittorio, Smith, Andrew, Sundh, Ulla Beckman, Tlustos, Christina, Wölfle , Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +24 more
core   +3 more sources

Differential Sphingosine-1-Phosphate Receptor-1 Protein Expression in the Dorsolateral Prefrontal Cortex Between Schizophrenia Type 1 and Type 2

Frontiers in Psychiatry, 2022
Understanding the etiology and treatment approaches in schizophrenia is challenged in part by the heterogeneity of this disorder. One encouraging progress is the growing evidence that there are subtypes of schizophrenia.
Ganesh B. Chand, Hao Jiang, J. Philip Miller, C. Harker Rhodes, Zhude Tu, Dean Foster Wong, Dean Foster Wong   +6 more
doaj   +1 more source

Synthesis and Evaluation of 125I Labeled Chalcone Derivatives Containing Bithiophene Moiety as Potential Aβ Probes

Journal of Isotopes, 2015
In continuation of the investigation on the bithiophene structure as potential Aβ probes, two halogenated chalcone derivatives containing bithiophene moiety were designed and evaluated as imaging probes for Aβ plaques.
PENG Cheng, CUI Meng-chao, LIANG Zhi-gang, LIU Ting-ting   +3 more
doaj   +1 more source