Results 41 to 50 of about 160,386 (240)

Characterizing the binding of TC-5619 and encenicline on the alpha7 nicotinic acetylcholine receptor using PET imaging in the pig

Frontiers in Neuroimaging
The alpha7 nicotinic acetylcholine receptor (α7-nAChR) has has long been considered a promising therapeutic target for addressing cognitive impairments associated with a spectrum of neurological and psychiatric disorders, including Alzheimer's disease ...
Janus H. Magnussen, Janus H. Magnussen, Anders Ettrup, Szabolcs Lehel, Dan Peters, Agnete Dyssegaard, Morten S. Thomsen, Morten S. Thomsen, Jens D. Mikkelsen, Jens D. Mikkelsen, Gitte M. Knudsen, Gitte M. Knudsen   +11 more
doaj   +1 more source

Measurement of Cell Adhesion and Migration Using Phosphor-Screen Autoradiography

BioTechniques, 1996
This study demonstrates the use of phosphor-screen autoradiography as a means of measuring cell adhesion and cell expansion on polymer surfaces.
B.A. Dalton, M. Dziegielewski, G. Johnson, P.A. Underwood, J.G. Steele   +4 more
doaj   +1 more source

The Periodic Replacement of Adhesive Setae in Pad Lamellae of Climbing Lizards Is Driven by Patterns of Corneous Layer Growth

Journal of Developmental Biology, 2022
The adhesive digital pads in some gecko and anoline lizards are continuously utilized for movements on vertical surfaces that may determine wear and a decrease of adhesion efficiency.
Lorenzo Alibardi
doaj   +1 more source

α-Synuclein Overexpression Increases Dopamine D2/3 Receptor Binding and Immune Activation in a Model of Early Parkinson’s Disease

Biomedicines, 2021
Progressive degeneration of dopaminergic neurons, immune activation, and α-synuclein pathology characterize Parkinson’s disease (PD). We previously reported that unilateral intranigral injection of recombinant adeno-associated viral (rAAV) vectors ...
Kathrine Stokholm, Majken Borup Thomsen, Jenny-Ann Phan, Line K. Møller, Cecilie Bay-Richter, Søren H. Christiansen, David P. D. Woldbye, Marina Romero-Ramos, Anne M. Landau   +8 more
doaj   +1 more source

Functional expression of the polymeric immunoglobulin receptor from cloned cDNA in fibroblasts. [PDF]

, 1986
The polymeric immunoglobulin receptor, a transmembrane protein, is made by a variety of polarized epithelial cells. After synthesis, the receptor is sent to the basolateral surface where it binds polymeric IgA and IgM.
Deitcher, DL, Mostov, KE, Neutra, MR
core  

Scientific Opinion on Flavouring Group Evaluation 302 (FGE.302): N-(2-methylcyclohexyl)-2,3,4,5,6-pentafluoro-benzamide from Chemical Group 30 [PDF]

, 2017
Publisher ...
Anastassiadou, Maria, Bolognesi, Claudia, Brimer, Leon, Castle, Laurence, Cravedi, Jean-Pierre, de Fátima Tavares Poças, Maria, EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Engel, Karl-Heinz, Fowler, Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kärenlampi, Sirpa, Mennes, Wim, Mulder, Gerard, Penninks, André, Rosaria Milana, Maria, Silano, Vittorio, Smith, Andrew, Sundh, Ulla Beckman, Tlustos, Christina, Wölfle , Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +24 more
core   +3 more sources

Repeated Clozapine Increases the Level of Serotonin 5-HT1AR Heterodimerization with 5-HT2A or Dopamine D2 Receptors in the Mouse Cortex

Frontiers in Molecular Neuroscience, 2018
G-protein–coupled receptor (GPCR) heterodimers are new targets for the treatment of schizophrenia. Dopamine D2 receptors and serotonin 5-HT1A and 5-HT2A receptors play an important role in neurotransmission and have been implicated in many human ...
Marta Szlachta, Maciej Kuśmider, Paulina Pabian, Joanna Solich, Magdalena Kolasa, Dariusz Żurawek, Marta Dziedzicka-Wasylewska, Agata Faron-Górecka   +7 more
doaj   +1 more source

Rabl's model of the interphase chromosome arrangement tested in Chinise hamster cells by premature chromosome condensation and laser-UV-microbeam experiments [PDF]

, 1982
In 1885 Carl Rabl published his theory on the internal structure of the interphase nucleus. We have tested two predictions of this theory in fibroblasts grown in vitro from a female Chinese hamster, namely (1) the Rabl-orientation of interphase ...
C Cremer, C Cremer, C Cremer, C Cremer, C Cremer, C Rabl, C Zorn, C Zorn, C. Cremer, C. Zorn, DE Comings, DE Comings, DM Pardoll, E. K. Luedtke, F Vogel, H Hoehn, H Zankl, H. Baumann, K Sperling, K Sperling, K Sperling, K. Sperling, KD Zang, L Avivi, L Hens, M Kirsch-Volders, M Kirsch-Volders, R Berezney, T Cremer, T. Cremer, Th Boveri, Th Boveri, V. Teuber, W Schnedl, Y Moroi   +34 more
core   +1 more source

The Exosome Subunit Rrp44 Plays a Direct Role in RNA Substrate Recognition [PDF]

, 2007
The exosome plays key roles in RNA maturation and surveillance, but it is unclear how target RNAs are identified. We report the functional characterization of the yeast exosome component Rrp44, a member of the RNase II family.
Anderson, James T., Schneider, Claudia, Tollervey, David   +2 more
core   +2 more sources

11C-Autoradiographs to Image Phloem Loading

Frontiers in Forests and Global Change, 2019
Generally, tree species load photoassimilates passively into the phloem, while herbaceous species load actively. These phloem loading strategies have implications for phloem sugar concentration and growth potential.
Michiel Hubeau, Jens Mincke, Jens Mincke, Christian Vanhove, Anaïs Pasiphaé Gorel, Adeline Fayolle, Jackie Epila, Olivier Leroux, Stefaan Vandenberghe, Kathy Steppe   +9 more
doaj   +1 more source