Results 81 to 90 of about 99,381 (174)

In vitro characterization of [125I]HY-3-24, a selective ligand for the dopamine D3 receptor

Frontiers in Neuroscience
IntroductionDopamine D3 receptor (D3R) ligands have been studied for the possible treatment of neurological and neuropsychiatric disorders. However, selective D3R radioligands for in vitro binding studies have been challenging to identify due to the high
Ji Youn Lee, Ho Young Kim, Paul Martorano, Aladdin Riad, Michelle Taylor, Robert R. Luedtke, Robert H. Mach   +6 more
doaj   +1 more source

Autoradiography [PDF]

CA: A Cancer Journal for Clinicians, 1958
openaire   +2 more sources

[¹²⁵I]IPC-Lecanemab: Synthesis and Evaluation of Aβ-Plaque-Binding Antibody and Comparison with Small-Molecule [¹⁸F]Flotaza and [¹²⁵I]IBETA in Postmortem Human Alzheimer’s Disease

Neurology International
Therapeutic antibodies for reducing Aβ plaque load in Alzheimer’s disease (AD) is currently making rapid progress. The diagnostic imaging of Aβ plaque load in AD has been underway and is now used in clinical studies.
Christopher Liang, Cayz G. Paclibar, Noresa L. Gonzaga, Stephanie A. Sison, Harman S. Bath, Agnes P. Biju, Jogeshwar Mukherjee   +6 more
doaj   +1 more source

A Bayesian Hierarchical Approach to Quasi-Replicate Dataset Modelling

Mathematics
It is very common for multiple experiments to be conducted under non-identical but similar conditions, perhaps because of implementation errors, natural variability in experimental material, or gradual drifting of experimental conditions. In the extremes
Hassan M. Aljohani, Robert G. Aykroyd
doaj   +1 more source

Enhanced activity localization and microscale dosimetry in alpha-emitter radiopharmaceutical therapy using integrated autoradiography and histological imaging

Scientific Reports
Alpha-emitter radiopharmaceutical therapy delivers highly localized radiation, offering potent therapeutic effects. However, microscale heterogeneity remains poorly characterized in vivo and may affect efficacy. This underscores the critical need for sub-
Sandeep Sahota, Krystal A. Quirindongo, Joseph Piccolo, Anupriya Chhabra, Nouran Zaid, Simin Deveauxbray, Kenechukwu C. Charles-Obi, Brian Miller, Robert F. Hobbs, George Sgouros, Remco Bastiaannet   +10 more
doaj   +1 more source

Toward Brain Na_V1.8 Imaging with [¹¹C]Suzetrigine. [PDF]

Pharmaceuticals (Basel)
Tokala R, Pearson TD, Mair BA, Bricault S, Wallace R, Wey HY, Hooker JM, Lee SJ.   +7 more
europepmc   +1 more source

Autoradiographie [PDF]

, 2017
A. M. Gressner, O. A. Gressner
openaire   +2 more sources

Autoradiography [PDF]

, 2020
openaire   +2 more sources

Use of Amplified Lewy Body Dementia Fibrils and Autoradiography to Characterize Binding of Radioligand Tg-1-90B to Alpha-Synuclein Fibrils in Postmortem Brain Tissue. [PDF]

Cells
O'Shea JY, Dhavale DD, Hwang H, Smith Z, Graham TJA, Mach RH, Kotzbauer PT.   +6 more
europepmc   +1 more source

Cerenkov luminescence microscopy: A novel approach for high-resolution radiotracer imaging. [PDF]

iScience
Alborghetti L, Vurro F, Belloli S, Rainone P, Valtorta S, Milani Capialbi M, Lacavalla MA, Pizzardi S, Moresco RM, Boschi F, Spinelli AE.   +10 more
europepmc   +1 more source