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Analysis of avenanthramides in oat products and estimation of avenanthramide intake in humans

Food Chemistry, 2018
Avenanthramides are phenolic compounds found only in oats, and are of interest due to suggested bioactivities, including anti-inflammatory effects and induction of apoptosis. The objective of this work was to optimise a high performance liquid chromatography (HPLC) method for analysis of avenanthramides in food, and analyse the avenanthramide content ...
Angela A, Pridal   +2 more
openaire   +2 more sources

Biosynthesis of oat avenanthramide phytoalexins

Phytochemistry, 1999
Abstract The biosynthesis of oat phytoalexins, avenanthramides, was investigated by administering labeled putative precursors to oat leaf segments treated with the elicitor, penta-N-acetylchitopentaose. Among the compounds tested, oat leaf segments incorporated [ring-UL-14C]anthranilic acid, [2,3,4,5,6-2H] l -phenylalanine and [1,2-13C]p-coumaric ...
Atsushi Ishihara   +2 more
openaire   +2 more sources

Stability of Oat Avenanthramides

Cereal Chemistry, 2001
ABSTRACTThe three main oat avenanthramides, N‐(4′‐hydroxy)‐(E)‐cinnamoyl‐5‐hydroxyanthranilic acid (Bp), N‐(4′‐hydroxy‐3′‐methoxy)‐(E)‐cinnamoyl‐5‐hydroxyanthranilic acid (Bf), and N‐(3′,4′‐dihydroxy)‐(E)‐cinnamoyl‐5‐hydroxyanthranilic acid (Bc), and their corresponding cinnamic acids, p‐coumaric (P), ferulic (F), and caffeic (C), were investigated for
Lena Häll Dimberg   +3 more
openaire   +1 more source

Avenanthramide C from Oats Protects Pyroptosis through Dependent ROS-Induced Mitochondrial Damage by PI3K Ubiquitination and Phosphorylation in Pediatric Pneumonia.

Journal of Agricultural and Food Chemistry, 2022
Oat containing rich β-glucan, polyphenols, flavonoids, saponins, alkaloids, and other substances shows good biological activities. Therefore, the present study aimed to uncover the possible mechanism and therapeutic effect of Avenanthramide C in ...
Zhichen Pu   +4 more
semanticscholar   +1 more source

New Dimeric Compounds of Avenanthramide Phytoalexin in Oats

The Journal of Organic Chemistry, 2007
Avenanthramide B is an oat phytoalexin produced in response to pathogen attack and elicitation. We found the formation of new dimers (1-5) of avenanthramide B in elicited oat leaves. The dimers were synthesized by a reaction of peroxidase and avenanthramide B in the presence of hydrogen peroxide.
Yozo, Okazaki   +4 more
openaire   +2 more sources

Avenanthramide C from underutilized oat glumes exhibits dual anti-oxidant and anti-thrombotic effects in oxidative damage and thrombosis models.

Food & Function
Avenanthramides (Avns), particularly Avn-C, are unique phenolic compounds found in oats, known for their anti-oxidant and anti-inflammatory effects. This study evaluated Avn-C's bioactivity using oxidative damage models in HUVECs induced by t-BOOH and ...
Li-Wei Wang   +11 more
semanticscholar   +1 more source

Tentative Avenanthramide‐Modifying Enzyme in Oats

Cereal Chemistry, 2003
ABSTRACTA decrease of the concentration of the synthetic avenanthramide N‐(4′‐hydroxy‐(E)‐cinnamoyl)‐5‐hydroxyanthranilic acid in a buffered slurry of milled oat groats (Avena sativa L.) was temperature and pH‐dependent, with a maximum rate at 30°C and pH 9.
Susanne Bryngelsson   +3 more
openaire   +1 more source

Oat Avenanthramide‐C Alleviates DSS‐Induced Colitis Through Regulating Intestinal Immune Activity and Gut Microbiota in Mice

Molecular Nutrition & Food Research
Oat avenanthramide‐C (AVN‐C) exhibits notable anti‐inflammatory and antioxidant properties, while its potential effects on inflammatory bowel disease (IBD) remain unclear. This study aimed to investigate the impact of AVN‐C on dextran sulfate sodium (DSS)
Gaoqi Ye   +5 more
semanticscholar   +1 more source

Avenanthramide-C prevents amyloid formation of bovine serum albumin

Biophysical Chemistry, 2020
The misfolding of protein and its assembly into amyloid fibrils with a characteristic β-sheet-rich secondary structure, cause a lot of illnesses. Polyphenols have been extensively studied as a class of amyloid inhibitors, whose effect depends on the position and number of hydroxyl groups around the flavone backbone.
Maria Guadalupe, Quiroz Vazquez   +3 more
openaire   +2 more sources

Microbial‐derived metabolites of oat avenanthramides

The FASEB Journal, 2016
Oat is a multifunctional crop nutritionally superior to many other unfortified cereals. It is commonly consumed as whole grains and known to provide healthy nutrients to humans. Oats contain a unique type of compounds, avenanthramides (AVAs), which are a group of substituted N ...
Aaron Yerke, Pei Wang, Shengmin Sang
openaire   +1 more source

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