Results 81 to 90 of about 1,420 (199)

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

BMEMat, Volume 3, Issue 3, September 2025.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan, Ye Zhu, Zhi Ye, Huayang Zhang, Junxi Wang, Guozhong Yi, Zhiyong Li, Rongyang Xu, Luyao Wang, Zhenzhen Wu, Songtao Qi, Guanglong Huang, Shanqiang Qu   +12 more
wiley   +1 more source

Gastrointestinal Tumors: Phytochemical and Drug Combinations Targeting the Hallmarks of Cancer

Applied Sciences, 2021
Cancer is a worldwide burden resulting in millions of deaths each year. In particular, gastrointestinal tumors are life-threatening malignancies and one of the leading reasons for death in developed countries.
Emanuele Salvatore Scarpa, Marco Giammanco, Mauro Magnani   +2 more
doaj   +1 more source

Functional Exploitation of Carob, Oat Flour, and Whey Permeate as Substrates for a Novel Kefir-Like Fermented Beverage: An Optimized Formulation [PDF]

, 2021
This study investigated the fortification of a carob-based kefir-like beverage (KLB) with whey permeate (WP) and oat flour (OF). The response surface method was used to show the effect of WP and OF concentrations on lactic acid bacteria and yeast cell ...
Ayed, Lamia, Di Cagno, Raffaella, Filannino, Pasquale, Mejri, Asma, M’hir, Sana, Tlais, Ali Zein Alabiden   +5 more
core   +1 more source

Oat Bran Supplementation Improves Glucose Metabolism, Food Addiction, and Gut Microbiota in Rats With High‐Fat Diet‐Induced Obesity

Food Frontiers, Volume 6, Issue 5, Page 2204-2230, September 2025.
ABSTRACT Oat bran (OB), a byproduct of the oat milling process, is a nutrient‐dense cereal cultivated in cool, dry mountainous regions and is known for its potential health benefits. To explore its obesity‐alleviating effects and the underlying mechanisms, we examined the influence of OB on glucose metabolism, appetite‐regulating hormones, gut ...
Xue Bai, Meili Zhang, Yakun Zhang, Yuanyuan Zhang, Rui Huo, Qixin Gu, Ying Miao   +6 more
wiley   +1 more source

Identification of methylated avenanthramides in human plasma

The FASEB Journal, 2016
Avenanthramides (AVs) are phytochemicals unique to oats consisting of an anthranilic acid and hydroxycinnamic acid linked by a pseudo‐peptide bond. We have demonstrated AV bioavailability to be low in hamsters and humans, suggesting they may be metabolized by phase II enzymes to facilitate their rapid excretion.
Jason Walsh, Jordan Haddock, Diane L. McKay, F. William Collins, Jeffrey B. Blumberg, C‐Y. Oliver Chen   +5 more
openaire   +1 more source

Cellular Senescence in Cancer: Mechanisms, Roles in Tumor Progression, and Therapeutic Implications

MedComm – Oncology, Volume 4, Issue 3, September 2025.
Senescent tumor cells in TME exhibit dual roles. “Angels” secrete SASPs/DAMPs to boost immunological clearance and antitumor immunity via MHC‐I upregulation; “Demons” produce tumor‐promoting SASPs recruiting MDSCs to drive malignancy. ABSTRACT Cellular senescence, a state of irreversible cell cycle arrest accompanied by a senescence‐associated ...
Jingrui Yan, Yu Zhang, Guohua Mao, Jun Yu, Tianxing Zhou, Jihui Hao   +5 more
wiley   +1 more source

Phenolic Compounds in Plant-Based Milk Alternatives from the Greek Market

Separations
Plant-based milk alternatives (PBMAs) are plant-based fluid products that are marketed as substitutes for regular milk. The nutrient composition of PBMA products can vary widely, depending on the plant source, processing methods, potential additives, etc.
Velisaria-Eleni Gerogianni, Christiana Mantzourani, Maria A. Theodoropoulou, Antonia Chiou, Maroula G. Kokotou   +4 more
doaj   +1 more source

New Insights Into the Use of Cereals and Pseudocereals in Fermented Beverages: Trends, Challenges, and Innovations

eFood, Volume 6, Issue 4, August 2025.
This review explores cereals and pseudocereals in fermented beverages, highlighting trends, challenges, and innovations supporting health, sustainability, and gluten‐free brewing. ABSTRACT Nowadays, cereals and pseudocereals are crucial in producing fermented drinks, conferring their nutritional, functional, and sensory properties.
Amal Sudaraka Samarasinghe, Fabiola Fernando, Kerthika Devi Athiyappan, Baojun Xu, Abu Saeid   +4 more
wiley   +1 more source

Chronic Effects of a Wild Green Oat Extract Supplementation on Cognitive Performance in Older Adults: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial [PDF]

, 2012
Background and aim: Preliminary evaluation of a wild green oat extract (WGOE) (Neuravena® ELFA®955, Frutarom, Switzerland) revealed an acute cognitive benefit of supplementation.
Abascal, Alison M. Coates, Berry, Bucci, Chen, Dik, Dodrill, Field, Gunstad, Janet Bryan, Jonathan D. Buckley, Jovanovski, Kalbe, Koenig, Krikorian, Mozolic, Muscari, Narelle M. Berry, Nieoullon, Peter R. C. Howe, Rachel H. X. Wong, Scholey, Sun, Uttl   +23 more
core   +5 more sources

Avenanthramide bioavailability and liver absorption in rats

The FASEB Journal, 2007
Avenanthramides (Avn) are antioxidants found exclusively in oats ( Avena sativa L.). The aim of this study was to determine the time course of Avn absorption into plasma and liver following their ingestion. Avn B p , B f
Ryan Koenig, Jonathan Dickman, Mitchell L. Wise, Li Li Ji   +3 more
openaire   +1 more source