Results 161 to 170 of about 136,222 (342)
Experimental Physiology, EarlyView.Abstract Sleep apnoea (SA) is ∼2 times more prevalent in men than women. However, this changes at menopause as the occurrence of SA increases and matches that of men. Menopause is a natural process, but it remains unclear why SA emerges only in a subpopulation of ageing women.
Danuzia Ambrozio‐Marques +4 more
wiley +1 more source
The role of aging on endothelial cell-cell junctions and pulmonary microvascular permeability in male mice. [PDF]
Physiol RepAging contributes to impairments in pulmonary microvascular endothelial cell‐cell junctions and barrier function, leading to an increased predisposition to injury. Created in BioRender. Gill, S. (2025) https://BioRender.com/l14r5v8 Abstract Pulmonary microvascular endothelial cell (PMVEC) intercellular junctions are critical for maintaining barrier ...
Manji A +10 more
europepmc +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Transforming growth factor (TGF)‐β2 and interleukin (IL)‐1β induced morphological and molecular changes consistent with endothelial‐to‐mesenchymal transition (EndMT) in HUVECs isolated from both pregnancies complicated by gestational diabetes (GDM) and non‐GDM pregnancies.
Abigail R. Byford +9 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.LIRI induces FABP4 secretion, driving lipid droplets accumulation in alveolar epithelial cells. FABP4 activates p38 MAPK/ULK1 signalling to inhibit lipophagy and promote lipid storage. Lipid droplets trigger epithelial–mesenchymal transition and disrupt alveolar barrier. Elevated FABP4 predicts ARDS in cardiopulmonary bypass patients.
Zihao Shen +11 more
wiley +1 more source
Mapping protein–protein interactions by mass spectrometry
Mass Spectrometry Reviews, Volume 45, Issue 1, Page 69-106, January/February 2026.Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu +4 more
wiley +1 more source
Aging Cell, Volume 25, Issue 1, January 2026.Our single nuclei RNA sequencing data reveal that long‐term calorie restriction in aged rhesus monkeys reduces neuroinflammation and preserves glial metabolism. In oligodendrocytes, calorie restriction attenuates an immune signature and promotes axonal proximity, while reducing a myelin‐laden microglia population.
Ana T. Vitantonio +13 more
wiley +1 more source