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Axin2 Deficiency Causes Hypomineralization and Delayed Tooth Development

Journal of Dental Research
Axin2 negatively regulates the Wnt signaling pathway, which plays a crucial role in multiple tooth development phases. This study aimed to investigate the effects of Axin2 deficiency on tooth development in zebrafish, which are categorized as polyphyodonts.
J. Song   +5 more
openaire   +2 more sources

[Association between AXIN2 polymorphism and oligodontia].

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2015
To explore the association between AXIN2 polymorphism and oligodontia in Chinese population.We employed 97 individuals diagnosed with sporadic non-syndromic oligodontia and 200 healthy control subjects. Their DNA was obtained from the whole blood or buccul swap samples and the genotyping was performed by polymerase chain reaction (PCR).Significant ...
Singwai, Wong   +4 more
openaire   +1 more source

Pharmacological targeting of Axin2 suppresses cell growth and metastasis in colorectal cancer

British Journal of Pharmacology, 2023
Zhao-Qiu Wu, Rong Fu, Li-Zhi Cheng
exaly  

AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration

Cell Stem Cell, 2020
Sebastian Bergling   +2 more
exaly  

Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development

Developmental Cell, 2023
Qing-Feng Wu   +2 more
exaly  

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