Results 171 to 180 of about 6,316,330 (345)

hnRNP R promotes O-GlcNAcylation of eIF4G and facilitates axonal protein synthesis

Nature Communications
Motoneurons critically depend on precise spatial and temporal control of translation for axon growth and the establishment and maintenance of neuromuscular connections.
Abdolhossein Zare, Saeede Salehi, Jakob Bader, Cornelius Schneider, Utz Fischer, Alexander Veh, Panagiota Arampatzi, Matthias Mann, Michael Briese, Michael Sendtner   +9 more
doaj   +1 more source

Amino-terminal proteolytic fragment of the axon growth inhibitor Nogo-A (Rtn4A) is upregulated by injury and promotes axon regeneration. [PDF]

J Biol Chem, 2023
Sekine Y, Wang X, Kikkawa K, Honda S, Strittmatter SM.   +4 more
europepmc   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Nerve Growth Factor Signaling Tunes Axon Maintenance Protein Abundance and Kinetics of Wallerian Degeneration [PDF]

Joseph A. Danos, Merve Addemir, Lily McGettigan, Daniel W. Summers   +3 more
openalex   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source

Membrane tension propagation couples axon growth and collateral branching. [PDF]

Sci Adv, 2022
Shi Z, Innes-Gold S, Cohen AE.
europepmc   +1 more source

The effect of systemic PTEN antagonist peptides on axon growth and functional recovery after spinal cord injury

, 2014
Yosuke Ohtake, Dongsun Park, P. M. Abdul‐Muneer, Hui Li, Bin Xu, Kartavya Sharma, George M. Smith, Michael E. Selzer, Shuxin Li   +8 more
openalex   +1 more source

Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug‐Releasing Capability for the Programmable Repair of Spinal Cord Injury

Advanced Science, EarlyView.
A novel drug‐loaded D/P‐g‐PSB nanogel‐incorporated hydrogel by the electrostatic attraction‐driven self‐assembling process. Sequential drug releasing property (melatonin is released first by physical diffusion, and then ibuprofen is released as the charge shielding effect and hydrogel degradation). This ion‐sensitive hydrogel platform with sequentially
Zhijian Wei, Susu Huang, Wencan Zhang, Jiayao Wen, Xiaolong Zhou, Wei He, Xiaoye Yang, Haifeng Wang, Guangxi Zhai, Bin Shi, Lin Jin, Dachuan Wang, Shiqing Feng, Lei Ye   +13 more
wiley   +1 more source

Stimulation of GHRH Neuron Axon Growth by Leptin and Impact of Nutrition during Suckling in Mice. [PDF]

Nutrients, 2023
Decourtye-Espiard L, Clemessy M, Leneuve P, Mire E, Ledent T, Le Bouc Y, Kappeler L.   +6 more
europepmc   +1 more source

Ciliary neurotrophic factor and fibroblast growth factor increase the speed and number of regenerating axons after optic nerve injury in adult Rana pipiens

, 2013
Giam S. Vega‐Meléndez, Jonathan M. Blagburn, Rosa E. Blanco   +2 more
openalex   +1 more source