Results 111 to 120 of about 104,244 (349)
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale +6 more
wiley +1 more source
Revisiting Netrin-1: One Who Guides (Axons)
Proper patterning of the nervous system requires that developing axons find appropriate postsynaptic partners; this entails microns to meters of extension through an extracellular milieu exhibiting a wide range of mechanical and chemical properties. Thus,
Nicholas P. Boyer +2 more
doaj +1 more source
A simple rule for axon outgrowth and synaptic competition generates realistic connection lengths and filling fractions [PDF]
Neural connectivity at the cellular and mesoscopic level appears very specific and is presumed to arise from highly specific developmental mechanisms.
Achacoso +64 more
core +2 more sources
Cbln1 regulates axon growth and guidance in multiple neural regions [PDF]
Peng Han +9 more
openalex +1 more source
Axon guidance: Crossing the midline [PDF]
Neurons that connect the two sides of the nervous system project their axons across the midline. New studies provide evidence for a conserved gatekeeping mechanism that controls this midline crossing.
openaire +2 more sources
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel +6 more
wiley +1 more source
Down-regulation of ROBO2 Expression in Prostate Cancers [PDF]
Several lines of evidence exist that axon guidance genes are involved in cancer pathogenesis. Axon guidance genes ROBO1 and ROBO2 are candidate tumor suppressor genes (TSG).
Nam Jin Yoo +2 more
core +1 more source
The axon guidance cue SEMA3A promotes the aggressive phenotype of basal-like PDAC [PDF]
Francesca Lupo +23 more
openalex +1 more source
Bioprinting Organs—Science or Fiction?—A Review From Students to Students
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu +18 more
wiley +1 more source

