Results 231 to 240 of about 105,575 (349)

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Calcitriol Modulates Hippocampal Axon Guidance Through Enhanced EfnA4-Mediated PI3K/AKT Signaling in an Autism Mouse Model. [PDF]

CNS Neurosci Ther
Gong T, Sun R, Bai J, Liu X, He C, Jiang Q, Wang Q, Qi Y, Ding W, Shen J, Lei L, Shan Z.   +11 more
europepmc   +1 more source

Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase β

, 1998
Sacha J. Holland, Elior Peles, Tony Pawson, Joseph Schlessinger   +3 more
openalex   +1 more source

Signaling Switch of the Axon Guidance Receptor Robo3 during Vertebrate Evolution [PDF]

, 2014
Pavol Zelina, Heike Blockus, Yvrick Zagar, Amélie Péres, François Friocourt, Zhuhao Wu, Nicolas Rama, Coralie Fouquet, Erhard Hohenester, Marc Tessier‐Lavigne, Jörn Schweitzer, Hugues Roest Crollius, Alain Chédotal   +12 more
openalex   +1 more source

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

Expanding ligand-receptor interaction networks for axon guidance: Structural insights into signal crosstalk and specificity. [PDF]

Curr Opin Neurobiol
Zhu S, Jaworski A, Meijers R.
europepmc   +1 more source

Molecular insights into the axon guidance molecules Sidestep and Beaten path. [PDF]

Front Physiol, 2022
Heymann C, Paul C, Huang N, Kinold JC, Dietrich AC, Aberle H.   +5 more
europepmc   +1 more source

Decision letter: Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons

, 2015

openalex   +1 more source

A Tangentially Sensitive Tactile Sensor Reveals the Stick‐Slip Mechanism and Enhances Robotic Tactile Sensing

Advanced Science, EarlyView.
An ultralight, multilayer anisotropic tactile sensor—an artificial Pacinian corpuscle—exhibits ultrahigh tangential sensitivity (1022 kPa−1) and spatiotemporal sensing. It discriminates static, sliding, and rolling contacts, detects incipient stick–slip via high‑frequency signatures, and enhances robotic touch (100%/98.18% accuracy for active/passive ...
Jinghui Wang, Xiaoyu Liu, Yujiao Du, Yepu Chen, Jieyi Guo, Linyuan Fan, Min Tang, Xiaofeng Qiao, Yuanjie Zhu, Zhiyang Zhang, Chaojie Dong, Lizhen Wang, Yubo Fan   +12 more
wiley   +1 more source

Nectin-like molecules/SynCAMs are required for post-crossing commissural axon guidance

, 2010
Vera Niederkofler, Thomas Baeriswyl, Regula Ott, Esther T. Stoeckli   +3 more
openalex   +1 more source