Results 281 to 290 of about 105,575 (349)

Quercetin Alleviates Diabetic Peripheral Neuropathy by Regulating Axon Guidance Factors and Inhibiting the Rho/ROCK Pathway in vivo and in vitro. [PDF]

Diabetes Metab Syndr Obes
Song W, Li Y, Jia Y, Xu L, Kang L, Yang Y, Wang S, Zhang Q, Wu Q.   +8 more
europepmc   +1 more source

Human Brain Contusions Contain Pathogenic Transmissible Species that Induce Progressive Cognitive Decline and Tau Pathology in Mice

Annals of Neurology, EarlyView.
Objective Traumatic brain injury (TBI) is an established risk factor for dementia, although the underlying mechanisms remain unclear. Our previous research demonstrated that a single severe TBI in wild‐type (WT) mice induces a prion‐like form of tau (tauTBI) that spreads throughout the brain, leading to memory deficits.
Gloria Vegliante, Francesca Pischiutta, Elena Restelli, Federico Moro, Maria Antonietta Chiaravalloti, Ilaria Raimondi, Ilaria Bertani, Ilaria Lisi, Eliana Sammali, Rosaria Pascente, Serena Scozzari, Laura Pasetto, Carly Douglas, Marco Locatelli, Fabrizio Ortolano, Valentina Bonetto, David J. Loane, Nino Stocchetti, Roberto Chiesa, Elisa R. Zanier   +19 more
wiley   +1 more source

Tet controls axon guidance in early brain development through glutamatergic signaling. [PDF]

iScience
Tran H, Le L, Singh BN, Kramer J, Steward R.   +4 more
europepmc   +1 more source

Neurofilament Proteoforms in Amyotrophic Lateral Sclerosis Are Different in Cerebrospinal Fluid and Blood

Annals of Neurology, EarlyView.
We used targeted immunopurification‐mass spectrometry (IP‐MS) to characterize human neurofilament light chain (NfL) proteoforms across various compartments to assess their alterations in amyotrophic lateral sclerosis (ALS). NfL is truncated in cerebrospinal fluid (CSF) and blood in patients with sporadic ALS (sALS) and these proteoforms differ between ...
John B. Coulton, Yingxin He, Melissa M. Budelier, Nicolas Barthélemy, Margaret D. Ireland, Miwei Hu, Danielle Graham, Toby Ferguson, James D. Berry, Randall J. Bateman, Timothy M. Miller, Cindy V. Ly   +11 more
wiley   +1 more source

UNC5C: Novel Gene Associated with Psychiatric Disorders Impacts Dysregulation of Axon Guidance Pathways. [PDF]

Genes (Basel)
Treccarichi S, Failla P, Vinci M, Musumeci A, Gloria A, Vasta A, Calabrese G, Papa C, Federico C, Saccone S, Calì F.   +10 more
europepmc   +1 more source

Conditioning Electrical Stimulation for Patients with Moderate or Severe Carpal Tunnel Syndrome: Double Blinded Randomized Controlled Trial

Annals of Neurology, EarlyView.
Objective Carpal tunnel syndrome (CTS) can drastically impair one's ability to work and interferes with activities of daily living. We recently demonstrated that, in rodents, conditioning electrical stimulation (CES) delivered to the nerve 7 days prior to surgery imparts a conditioning lesion‐like effect by accelerating the rate of regeneration along ...
Yusuke Osaki, Jaret L. Olson, Michael J. Morhart, Matthew W. Curran, Douglas W. Zochodne, K. Ming Chan, on behalf of the Central and Northern Alberta Peripheral Nerve Injury Research Consortium, Hollie Power, Adil Ladak, Lindsay Hubenig, Alto Lo, Christine Webber, Karyne Rabey, Andrew Jack, Joe Watt, Mithun Rajshekar, Ellen Lee, Glyn Murgatroyd, Dan Yeung, Kathleen O'Grady   +19 more
wiley   +1 more source

Bioprinted Excitable Tissues with Multistimulation Systems for Promoting Function and Maturation

Advanced NanoBiomed Research, EarlyView.
This review provides an overview of stimulation strategies used to enhance the functional maturation of bioprinted excitable tissues. It addresses key limitations in physiological performance of bioprinted excitable tissues, outlines major stimulation modalities—including electrical, mechanical, optical, magnetic, ultrasound, and hybrid—and examines ...
Uijung Yong, Jinseon Park, Jinah Jang
wiley   +1 more source

A human DCC variant causing mirror movement disorder reveals that the WAVE regulatory complex mediates axon guidance by netrin-1-DCC. [PDF]

Sci Signal
Chaudhari K, Zhang K, Yam PT, Zang Y, Kramer DA, Gagnon S, Schlienger S, Calabretta S, Michaud JF, Collins M, Wang J, Srour M, Chen B, Charron F, Bashaw GJ.   +14 more
europepmc   +1 more source

Selective Promotion of Retinal Organoid Attachment and Differentiation by Amine‐ and Hydroxyl‐Modified Surfaces

Advanced NanoBiomed Research, EarlyView.
Engineered biomaterial interfaces critically control retinal organoid development. This study examines how surface modifications (amine, hydroxyl, phenyl, and methyl groups) dictate organoid response. Hydrophilic surfaces markedly increase migration and foster retinal ganglion cell differentiation.
Luis Marcos, Charlie Hall, Eric J. Hill, Samantha L. Wilson, Paul Roach   +4 more
wiley   +1 more source

Axon Guidance as a Random Walk, 2014 CSHL Meeting Poster

, 2014
William G. Wadsworth, Xia Tang, Aseei Al-Aamiri, Won Suk Lee, Ahmed Mohamed   +4 more
openalex   +1 more source