Results 51 to 60 of about 899,641 (334)
Floor plate-derived netrin-1 is dispensable for commissural axon guidance
Nature, 2017 Netrin-1 is an evolutionarily conserved, secreted extracellular matrix protein involved in axon guidance at the central nervous system midline. Netrin-1 is expressed by cells localized at the central nervous system midline, such as those of the floor ...
C. Dominici +8 more
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Axon guidance: Crossing the midline [PDF]
Current Biology, 1998 Neurons that connect the two sides of the nervous system project their axons across the midline. New studies provide evidence for a conserved gatekeeping mechanism that controls this midline crossing.
openaire +3 more sources
Decreased expression of axon-guidance receptors in the anterior cingulate cortex in autism
Molecular Autism, 2011 Background Axon-guidance proteins play a crucial role in brain development. As the dysfunction of axon-guidance signaling is thought to underlie the microstructural abnormalities of the brain in people with autism, we examined the postmortem brains of ...
Suda Shiro +15 more
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Cell migration and axon guidance at the border between central and peripheral nervous system
Science, 2019 Neurons negotiating boundaries Barriers around the brain and spinal cord separate central from peripheral nervous systems, yet the two systems are interlinked.
T. A. Suter, Alexander Jaworski
semanticscholar +1 more source
Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin
eLife, 2019 Developing neurons of the peripheral nervous system reach their targets via cues that support directional growth, a process known as axon guidance.
Denise M Poltavski +5 more
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Motor axon guidance in Drosophila
Seminars in Cell & Developmental Biology, 2019 The Drosophila motor system starts to assemble during embryonic development. It is composed of 30 muscles per abdominal hemisegment and 36 motor neurons assembling into nerve branches to exit the CNS, navigate within the muscle field and finally establish specific connections with their target muscles. Several families of guidance molecules that play a
Aref Arzan Zarin, Juan-Pablo Labrador
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Axon guidance pathway genes are associated with schizophrenia risk
Experimental and Therapeutic Medicine, 2018 In the present study, we analyzed schizophrenia (SCZ)-related genome-wide association studies (GWAS) to identify genes and pathways associated with SCZ.
Zhichao Wang +5 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objectives Intravenous immunoglobulin (IVIg) is an effective treatment for Guillain–Barré syndrome (GBS), but recovery varies between patients. This study aims to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of a single and a second IVIg dose (SID) in patients with GBS.
Sander J. van Tilburg +7 more
wiley +1 more source
Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons
Cell Reports, 2015 Axon guidance relies on precise translation of extracellular signal gradients into local changes in cytoskeletal dynamics, but the molecular mechanisms regulating dose-dependent responses of growth cones are still poorly understood.
Martin Balastik +15 more
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A developmental timing switch promotes axon outgrowth independent of known guidance receptors. [PDF]
PLoS Genetics, 2010 To form functional neuronal connections, axon outgrowth and guidance must be tightly regulated across space as well as time. While a number of genes and pathways have been shown to control spatial features of axon development, very little is known about ...
Katherine Olsson-Carter, Frank J Slack
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