Results 111 to 120 of about 769,118 (313)
Cell Death and Disease, 2018 Cerebral ischemia causes severe cell death or injury including axon breakdown or retraction in the brain. Axon regeneration is crucial for the functional recovery of injured neurons or brains after ischemia/reperfusion (I/R); however, this process has ...
X. Xiong +8 more
semanticscholar +1 more source
The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges
Advanced Science, EarlyView.This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li +3 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2017 Limited axon regeneration in the injured adult mammalian central nervous system (CNS) usually results in irreversible functional deficits. Both the presence of extrinsic inhibitory molecules at the injury site and the intrinsically low capacity of adult ...
Vinicius T. Ribas, Marcos R. Costa
doaj +1 more source
Scientific Reports, 2017 Spinal cord injuries (SCI) often lead to persistent neurological dysfunction due to failure in axon regeneration. Unfortunately, currently established treatments, such as direct drug administration, do not effectively treat SCI due to rapid drug ...
L. Nguyen +5 more
semanticscholar +1 more source
Progress and Perspectives in 2D Piezoelectric Materials for Piezotronics and Piezo‐Phototronics
Advanced Science, EarlyView.This review examines advancements in 2D materials, focusing on their applications in piezotronics and piezo‐phototronics. It discusses key materials like TMDs, h‐BN, and phosphorene, highlighting their unique mechanical, electronic, and optical properties.
Fengyi Pang +6 more
wiley +1 more source
Adult Mouse Retina Explants: From ex vivo to in vivo Model of Central Nervous System Injuries
Frontiers in Molecular Neuroscience, 2020 In mammals, adult neurons fail to regenerate following any insult to adult central nervous system (CNS), which leads to a permanent and irreversible loss of motor and cognitive functions.
Julia Schaeffer +4 more
doaj +1 more source
Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway
Science, 2008 The failure of axons to regenerate is a major obstacle for functional recovery after central nervous system (CNS) injury. Removing extracellular inhibitory molecules results in limited axon regeneration in vivo.
Kevin K. Park +10 more
semanticscholar +1 more source
Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices
Advanced Science, EarlyView.In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley +1 more source
Extreme value statistics of nerve transmission delay [PDF]
Nerve transmission delay is an important topic in neuroscience. Spike signals fired or received at the dendrites of a neuron travel from the axon to the presynaptic cell. The spike signal triggers a chemical reaction at the synapse, wherein a presynaptic cell transfers neurotransmitters to the postsynaptic cell, and regenerates electrical signals by a ...
arxiv +1 more source
Developmental Neurobiology, 2018 Injury to the brain and spinal cord has devastating consequences because adult central nervous system (CNS) axons fail to regenerate. Injury to the peripheral nervous system (PNS) has a better prognosis, because adult PNS neurons support robust axon ...
Veselina Petrova, R. Eva
semanticscholar +1 more source