Results 131 to 140 of about 938,041 (332)
Transplanted olfactory ensheathing cells promote regeneration of cut adult rat optic nerve axons
, 2003 Transplantation of olfactory ensheathing cells into spinal cord lesions promotes regeneration of cut axons into terminal fields and functional recovery.
Raisman, G. +4 more
core
Activating immune pathways promotes axon regeneration
, 2021 Interferon-γ (IFN-γ) is involved in normal neurodevelopment and pathological neuroinflammation. However, it is still unclear whether boosting neuronal IFN-γ signaling could affect neural repair and what is the functional downstream of IFN-γ in neurons ...
Wang, Xu
core
Advanced Science, EarlyView.Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari +3 more
wiley +1 more source
PLoS GeneticsThe pathway for axon regeneration in Caenorhabditis elegans is activated by SVH-1, a growth factor belonging to the HGF/plasminogen family. SVH-1 is a dual-function factor that acts as an HGF-like growth factor to promote axon regeneration and as a ...
Tatsuhiro Shimizu +3 more
doaj +1 more source
eLife, 2016 Axon injury triggers dramatic changes in gene expression. While transcriptional regulation of injury-induced gene expression is widely studied, less is known about the roles of RNA binding proteins (RBPs) in post-transcriptional regulation during axon ...
Lizhen Chen +8 more
doaj +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
Advanced Science, EarlyView.We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Cell Reports, 2014 Precise regulation of microtubule (MT) dynamics is increasingly recognized as a critical determinant of axon regeneration. In contrast to developing neurons, mature axons exhibit noncentrosomal microtubule nucleation.
Marian Chuang +5 more
doaj +1 more source
Determinants of axonal regeneration.
Histology and histopathology, 1997 Axons often regrow to their targets and lost functions may be restored after an injury in the peripheral nervous system. In contrast, axonal regeneration is generally very limited after injuries in the central nervous system, and functional impairment is usually permanent.
openaire +2 more sources
Protein deacetylases and axonal regeneration
Neural Regeneration Research, 2015 10.4103/1673-5374.158333 ; Neural Regeneration Research ; 10 ; 6 ; 870 ...
Ng F., Tang B.L.
openaire +3 more sources
Advanced Science, EarlyView.This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang +14 more
wiley +1 more source