Results 161 to 170 of about 769,118 (313)
Exploration, EarlyView.Targeting mitochondrial dysfunction presents a potential therapeutic approach for treating spinal cord injury. We have successfully designed and synthesized a functional Se@NADH nanodrug system. This system offers neuroprotective and neuroregenerative benefits by modulating mitochondrial function and neutralizing reactive oxygen species, thereby ...
Guibin Gao +12 more
wiley +1 more source
Andrology, Volume 11, Issue 2, Page 358-371, February 2023., 2023 Abstract Background The incidence of diabetic erectile dysfunction (ED) is rapidly increasing, and due to the severe angiopathy caused by diabetes, current drugs are ineffective at treating ED. Insulin‐like growth factor‐binding protein 5 (IGFBP5) promotes cell death and induces apoptosis in various cell types.
Jiyeon Ock +5 more
wiley +1 more source
The efficacy of PDE5 inhibitors in diabetic patients
Andrology, Volume 11, Issue 2, Page 245-256, February 2023., 2023 Abstract Background Phosphodiesterase 5 inhibitors (PDE5i), since their introduction in the late 1990s, have proven their efficacy in treating several conditions, predominantly pulmonary hypertension and erectile dysfunction where they remain the first‐line therapeutic option.
Agnieszka Swiecicka
wiley +1 more source
Functional Recovery of Paraplegic Rats and Motor Axon Regeneration in Their Spinal Cords by Olfactory Ensheathing Glia [PDF]
, 2000 Almudena Ramón‐Cueto +3 more
openalex +1 more source
Glia, EarlyView.Comprehensive analysis of cortical astrocyte gene expression across the lifespan. Profiling dynamic changes of key astrocyte genes reveals functional shifts. Astrocytes contribute to gene‐length‐dependent transcription decline in the aging brain. ABSTRACT Astrocytes are the most abundant glial cell type in the central nervous system (CNS).
Xiaoran Wei +2 more
wiley +1 more source
Spinal Cord Repair: Strategies to Promote Axon Regeneration
Neurobiology of Disease, 2001 Neurons in the central nervous system have a remarkable capacity to regenerate their transected axons when provided with an appropriate growth environment.
Lisa McKerracher
doaj
Lens Injury Stimulates Axon Regeneration in the Mature Rat Optic Nerve [PDF]
, 2000 Steven P. Leon +4 more
openalex +1 more source
Intrinsic mechanisms of neuronal axon regeneration
Nature Reviews Neuroscience, 2018 Marcus Mahar, V. Cavalli
semanticscholar +1 more source
Research progress of neurovascular units involved in ischemic stroke
Ibrain, EarlyView.The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang +4 more
wiley +1 more source
Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons
eLifeSensory dorsal root ganglion (DRG) neurons have a unique pseudo-unipolar morphology in which a stem axon bifurcates into a peripheral and a central axon, with different regenerative abilities.
Ana Catarina Costa +11 more
doaj +1 more source