Results 171 to 180 of about 50,535 (307)

Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways

, 2011
Paola Nix, Naoki Hisamoto, Kunihiro Matsumoto, Michael J. Bastiani   +3 more
openalex   +2 more sources

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Decision letter: Co-targeting myelin inhibitors and CSPGs markedly enhances regeneration of GDNF-stimulated, but not conditioning-lesioned, sensory axons into the spinal cord

, 2020
Veronica J. Tom, Jerry Silver
openalex   +1 more source

Determinants of directional specificity in the regeneration of lamprey spinal axons [PDF]

, 1986
S. A. Mackler, HS Yin, ME Selzer
openalex   +1 more source

Guidance of regenerating motor axons in larval and juvenile bullfrogs

, 2021
M. T. Lee, P. B. Farel
openalex   +1 more source

AI‐Assisted Customizable SERS‐Based Aptasensor for Label‐Free, Rapid, and Sensitive Detection of Tau: Comparative Analysis Using Random Forest and Convolutional Neural Networks

Analysis &Sensing, EarlyView.
A customizable SERS‐based aptasensor platform integrates aptamer‐functionalized gold nanoparticles with machine learning models (RF and CNN) to detect tau protein, a key biomarker for Alzheimer's disease. This rapid, label‐free detection system achieves a detection limit of 100 pM, enabling early diagnosis and monitoring of disease progression.
Farbod Ebrahimi, Farshad Ebrahimi, Anjali Kumari, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Extracellular Vesicle Metabolomics Holds Promise for Adult Axon Regeneration. [PDF]

Metabolites
Cabrera Gonzalez MD, Watson J, Leal L, Moceri I, Plummer C, Mahato B, Fouda AY, Bhattacharya SK.   +7 more
europepmc   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Regulation of nuclear transport of the transcriptional factor REST improves axon regeneration in peripheral nerves. [PDF]

Mol Med Rep
Suzuki T, Naito K, Kubota D, Ueno Y, Negishi-Koga T, Yamamoto Y, Kawakita S, Imazu N, Kawamura K, Hattori N, Ishijima M.   +10 more
europepmc   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source