Results 171 to 180 of about 769,118 (313)
Investigating the role of SARM1 in central nervous system
Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang+4 more
wiley +1 more source
Engineered Living Energy Materials
Engineered living energy materials (ELEMs) are nascent research frontier for enabling sustainable energy conversion and storage. These materials exhibit unique characteristics such as self‐regeneration, biodegradability, environmental response, and evolutionary adaptability. This paper overviews different energy conversion bio‐modules, summarizes their
Xinyi Yuan+14 more
wiley +1 more source
Selective Innervation of Retinorecipient Brainstem Nuclei by Retinal Ganglion Cell Axons Regenerating through Peripheral Nerve Grafts in Adult Rats [PDF]
Marcelino Avilés‐Trigueros+3 more
openalex +1 more source
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang+17 more
wiley +1 more source
Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi+6 more
wiley +1 more source
The multiscale mechanics of axon durotaxis [PDF]
During neurodevelopment, neuronal axons navigate through the extracellular environment, guided by various cues to establish connections with distant target cells. Among other factors, axon trajectories are influenced by heterogeneities in environmental stiffness, a process known as durotaxis, the guidance by substrate stiffness gradients.
arxiv
Lesioned corticospinal tract axons regenerate in myelin-free rat spinal cord.
T. Savio, Martin E. Schwab
openalex +1 more source
Axon regeneration: Vaccinating against spinal cord injury [PDF]
Marie T. Filbin
openalex +1 more source
A Diffusion MRI model for axonal damage quantification based on axial diffusivity reduction in axons: a Monte Carlo simulation study [PDF]
Axonal damage is the primary pathological correlate of long-term impairment in multiple sclerosis (MS). Previous work has demonstrated a strong, quantitative relationship between decrease in axial diffusivity and axonal damage. In the present work, we develop an extension of diffusion basis spectrum imaging (DBSI) which can be used to quantify the ...
arxiv