Results 161 to 170 of about 938,041 (332)
Stromal Regulation of Tumor Perineural Invasion: A Multicellular and Neuro‐Ecological Perspective
Advanced Science, EarlyView.This review reframes perineural invasion (PNI) as a dynamic, multicellular process within the tumor–nerve–stromal ecosystem. The authors delineate how cancer‐associated fibroblasts, Schwann cells, and immune cells remodel the neural niche to facilitate tumor spread.
Xiaoyang Lin +4 more
wiley +1 more source
Roles of mTOR in regulating mammalian central axon regeneration
, 2019 The failure of CNS axon regeneration is the major obstacle for functional recovery after traumatic injury. Exploring the mechanisms to promote axon regeneration is essential for the potential clinical trials.
Yang, Chao
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Cell Biology of Axon Degeneration and Regeneration In Vivo
, 2021 Axons are fundamental connective units that mediate information flow in nervous systems. Axon degeneration breaks neural circuits and is a hallmark of neurodegenerative diseases. Axon regeneration has the potential to repair damaged circuits.
Ding, Chen
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Advanced Science, EarlyView.A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky +15 more
wiley +1 more source
, 2010 Subsequent to neuronal injury, increased levels of protein synthesis accompany associated rises in transcription factor expression. Two transcription factors involved in the cellular stress response are c-Jun and ATMIN. Neuron-specific deletion of c-Jun
Ruff, C.A.D.B.
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Advanced Electronic Materials, EarlyView.A fully coupled FEM–HH model shows that ideally capacitive microelectrodes can achieve lower charge‐density thresholds than Faradaic contacts under current‐controlled stimulation. The advantage stems from the dynamics of surface current density on capacitive interfaces, which redirects current beneath adherent neurons.
Aleksandar Opančar +2 more
wiley +1 more source
Neurogenesis and apoptosis in the developmentally regulated loss of spinal cord regeneration.
, 2006 Unlike the adult mammal, the chick can successfully regenerate its spinal cord until embryonic day (E) 13. Multiple factors may contribute to the subsequent loss of regenerative capacity, although most research has concentrated on axonal re-growth ...
Whalley, K.A., Whalley, Katherine Ann
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Accurate Synapse Regeneration Despite Ablation of the Distal Axon Segment
, 1996 In each body ganglion of the leech Hirudo medicinalis there is a single S‐cell. After an S‐cell axon is severed, it regenerates along its surviving distal segment and reconnects with its synaptic target, the axon of the neighbouring S‐cell.
Muller, Kenneth J +3 more
core +1 more source
Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics
Advanced Electronic Materials, EarlyView.Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim +7 more
wiley +1 more source
Axon regeneration genes identified by RNAi screening in C. elegans [PDF]
, 2014 pre-printAxons of the mammalian CNS lose the ability to regenerate soon after development due to both an inhibitory CNS environment and the loss of cell-intrinsic factors necessary for regeneration.
Nix, Paola; Hammarlund, Marc; Hauth, Linda; Lachnit, Martina; Bastiani, Michael +1 more
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