Contemporary insight into diffuse axonal injury [PDF]
Folia Medica, 2021 Diffuse axonal injury (DAI) is present in approximately 50% of the cases with severe traumatic brain injury. It is one of the leading causes of morbidity and mortality among children and young individuals worldwide.
Polina Angelova +3 more
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Current Opportunities for Clinical Monitoring of Axonal Pathology in Traumatic Brain Injury
Frontiers in Neurology, 2017 Traumatic brain injury (TBI) is a multidimensional and highly complex disease commonly resulting in widespread injury to axons, due to rapid inertial acceleration/deceleration forces transmitted to the brain during impact.
Parmenion P. Tsitsopoulos +4 more
doaj +1 more source
Characterizing brain structures and remodeling after TBI based on information content, diffusion entropy. [PDF]
PLoS ONE, 2013 To overcome the limitations of conventional diffusion tensor magnetic resonance imaging resulting from the assumption of a Gaussian diffusion model for characterizing voxels containing multiple axonal orientations, Shannon's entropy was employed to ...
Niloufar Fozouni +13 more
doaj +1 more source
Neurological consequences of traumatic brain injuries in sports. [PDF]
, 2015 Traumatic brain injury (TBI) is common in boxing and other contact sports. The long term irreversible and progressive aftermath of TBI in boxers depicted as punch drunk syndrome was described almost a century ago and is now widely referred as chronic ...
Zetterberg, H +5 more
core +1 more source
Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury
Molecular Neurodegeneration, 2017 Background Optic nerve injury is an important pathological component in neurodegenerative diseases such as traumatic optic neuropathies and glaucoma. The molecular signaling pathway(s) critical for retinal ganglion cell (RGC) death after axonal insult ...
Stephanie B. Syc-Mazurek +4 more
doaj +1 more source
ATF3 upregulation in glia during Wallerian degeneration: differential expression in peripheral nerves and CNS white matter [PDF]
, 2004 Background: Many changes in gene expression occur in distal stumps of injured nerves but the transcriptional control of these events is poorly understood.
Coffin, RS +20 more
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Analysis of the C/EBP family of transcription factors in neuronal repair [PDF]
, 2009 PhDNeurons within the peripheral nervous system (PNS) have a remarkable ability to repair themselves after injury; however, neurons within the central nervous system (CNS) do not spontaneously regenerate.
López de Heredia, Luis
core +3 more sources
Axon degeneration: make the Schwann cell great again
Neural Regeneration Research, 2017 Axonal degeneration is a pivotal feature of many neurodegenerative conditions and substantially accounts for neurological morbidity. A widely used experimental model to study the mechanisms of axonal degeneration is Wallerian degeneration (WD), which ...
Keit Men Wong +2 more
doaj +1 more source
Localized Axolemma Deformations Suggest Mechanoporation as Axonal Injury Trigger
Frontiers in Neurology, 2020 Traumatic brain injuries are a leading cause of morbidity and mortality worldwide. With almost 50% of traumatic brain injuries being related to axonal damage, understanding the nature of cellular level impairment is crucial.
Annaclaudia Montanino +3 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2021 Most diabetes patients eventually suffer from peripheral nerve degeneration. Unfortunately, there is no treatment for the condition and its mechanisms are not well understood.
James I. Jones +10 more
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