Results 41 to 50 of about 1,099,148 (284)
Cognitive Sequelae of Diffuse Axonal Injury [PDF]
Archives of Neurology, 2006 The results of recent studies on cognitive disability after traumatic brain injury-associated diffuse axonal injury (DAI) are inconsistent. In these studies, the diagnosis of DAI relied on cranial computed tomography.To further clarify the extent and severity of a possibly DAI-associated cognitive impairment by the use of magnetic resonance imaging ...
Scheid, R. +4 more
openaire +3 more sources
Axonal Injury Following Focal Cerebral Ischaemia [PDF]
, 1998 Myelinated axons are essential for the normal functioning of the brain. Since myelinated axons, like grey matter, are dependent on a continuous supply of energy, it is likely that ischaemic injury compromises axonal function as well as that of the ...
Yam, Philippa S
core +6 more sources
Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice [PDF]
, 2010 The motor axonal variant of Guillain-Barré syndrome is associated with anti-GD1a immunoglobulin antibodies, which are believed to be the pathogenic factor. In previous studies we have demonstrated the motor terminal to be a vulnerable site.
Halstead, S. +7 more
core +2 more sources
Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse [PDF]
, 2012 Mice overexpressing proteolipid protein (PLP) develop a leukodystrophy-like disease involving cytotoxic, CD8+ T-lymphocytes. Here we show that these cytotoxic T-lymphocytes perturb retrograde axonal transport.
Groh Janos +47 more
core +1 more source
A growing field: The regulation of axonal regeneration by Wnt signaling
Neural Regeneration Research, 2018 The canonical Wnt/β-catenin pathway is a highly conserved signaling cascade that plays critical roles during embryogenesis. Wnt ligands regulate axonal extension, growth cone guidance and synaptogenesis throughout the developing central nervous system ...
Armando L Garcia +3 more
doaj +1 more source
Neurotrauma Reports, 2023 Penetrating traumatic brain injury (pTBI) is increasingly survivable, but permanently disabling as adult mammalian nervous system does not regenerate. Recently, our group demonstrated transplant location-dependent neuroprotection and safety of clinical ...
MaryLourdes Andreu +11 more
doaj +1 more source
Inhibiting store-operated calcium entry attenuates white matter secondary degeneration following SCI
Neurobiology of Disease, 2020 Axonal degeneration plays a key role in the pathogenesis of numerous neurological disorders including spinal cord injury. After the irreversible destruction of the white matter elements during the primary (mechanical) injury, spared axons and their ...
Ben C. Orem +2 more
doaj +1 more source
NeuroImage, 2020 We describe a practical two-dimensional (2D) diffusion MRI framework to deliver specificity and improve sensitivity to axonal injury in the spinal cord.
Dan Benjamini +7 more
doaj +1 more source
Rapid and Reversible Development of Axonal Varicosities: A New Form of Neural Plasticity
Frontiers in Molecular Neuroscience, 2021 Axonal varicosities are enlarged, heterogeneous structures along axonal shafts, profoundly affecting axonal conduction and synaptic transmission. They represent a key pathological feature believed to develop via slow accumulation of axonal damage that ...
Chen Gu
doaj +1 more source
Acta Neuropathologica Communications, 2022 Uniaxial stretch is believed to drive diffuse axonal injury (DAI) in mild traumatic brain injury (mTBI). Axonal varicosities are enlarged structures along axonal shafts and represent a hallmark feature of DAI.
Chao Sun +4 more
doaj +1 more source