Results 1 to 10 of about 171,690 (236)

Predicting the distribution of serotonergic axons: a supercomputing simulation of reflected fractional Brownian motion in a 3D-mouse brain model

Frontiers in Computational Neuroscience, 2023
The self-organization of the brain matrix of serotonergic axons (fibers) remains an unsolved problem in neuroscience. The regional densities of this matrix have major implications for neuroplasticity, tissue regeneration, and the understanding of mental ...
Skirmantas Janušonis, Justin H. Haiman, Ralf Metzler, Ralf Metzler, Thomas Vojta   +4 more
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Multiple Copies of microRNA Binding Sites in Long 3′UTR Variants Regulate Axonal Translation

Cells, 2023
Rapid responses to changes within subcellular compartments of highly polarized cells, such as neuron axons, depend on local translation and post-transcriptional regulation.
Luba Farberov, Ariel Ionescu, Yazeed Zoabi, Guy Shapira, Amjd Ibraheem, Yosi Azan, Eran Perlson, Noam Shomron   +7 more
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Probing brain tissue microstructure with MRI: principles, challenges, and the role of multidimensional diffusion-relaxation encoding

NeuroImage, 2023
Diffusion MRI uses the random displacement of water molecules to sensitize the signal to brain microstructure and to properties such as the density and shape of cells. Microstructure modeling techniques aim to estimate these properties from acquired data
Björn Lampinen, Filip Szczepankiewicz, Jimmy Lätt, Linda Knutsson, Johan Mårtensson, Isabella M. Björkman-Burtscher, Danielle van Westen, Pia C. Sundgren, Freddy Ståhlberg, Markus Nilsson   +9 more
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Collagen‐rich deposit formation in the sciatic nerve after injury and surgical repair: A study of collagen‐producing cells in a rabbit model

Brain and Behavior, 2020
Introduction Posttraumatic scarring of peripheral nerves produces unwanted adhesions that block axonal growth. In the context of surgical nerve repair, the organization of the scar tissue adjacent to conduits used to span the gap between the stumps of ...
Jolanta Fertala, Michael Rivlin, Mark L. Wang, Pedro K. Beredjiklian, Andrzej Steplewski, Andrzej Fertala   +5 more
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Pseudorabies Virus Mutants Lacking US9 Are Defective in Cytoplasmic Assembly and Sorting of Virus Particles into Axons and Not in Axonal Transport

Viruses, 2023
Herpes simplex virus (HSV) and varicella zoster virus (VZV) rely on transport of virus particles in neuronal axons to spread from sites of viral latency in sensory ganglia to peripheral tissues then on to other hosts.
Steven Adamou, Adam Vanarsdall, David C. Johnson   +2 more
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Ontogenetic Shifts in the Number of Axons in the Olfactory Tract and Optic Nerve in Two Species of Deep-Sea Grenadier Fish (Gadiformes: Macrouridae: Coryphaenoides)

Frontiers in Ecology and Evolution, 2018
Neuroanatomical studies of the peripheral sense organs and brains of deep-sea fishes are particularly useful for predicting their sensory capabilities and ultimately their behavior.
Thomas J. Lisney, Thomas J. Lisney, Hans-Joachim Wagner, Shaun P. Collin, Shaun P. Collin   +4 more
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Decellularized skeletal muscles display neurotrophic effects in three‐dimensional organotypic cultures

Stem Cells Translational Medicine, 2020
Skeletal muscle decellularization allows the generation of natural scaffolds that retain the extracellular matrix (ECM) mechanical integrity, biological activity, and three‐dimensional (3D) architecture of the native tissue. Recent reports showed that in
Paolo Raffa, Valentina Scattolini, Mattia Francesco Maria Gerli, Silvia Perin, Meihua Cui, Paolo De Coppi, Nicola Elvassore, Paola Caccin, Camilla Luni, Anna Urciuolo   +9 more
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Interplay between kinesin-1 and cortical dynein during axonal outgrowth and microtubule organization in Drosophila neurons

eLife, 2015
In this study, we investigated how microtubule motors organize microtubules in Drosophila neurons. We showed that, during the initial stages of axon outgrowth, microtubules display mixed polarity and minus-end-out microtubules push the tip of the axon ...
Urko del Castillo, Michael Winding, Wen Lu, Vladimir I Gelfand   +3 more
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Loss of highwire Protects Against the Deleterious Effects of Traumatic Brain Injury in Drosophila Melanogaster

Frontiers in Neurology, 2020
Traumatic brain injury is a major global cause of death and disability. Axonal injury is a major underlying mechanism of TBI and could represent a major therapeutic target.
Ciaran S. Hill, Ciaran S. Hill, Jemeen Sreedharan, Jemeen Sreedharan, Andrea Loreto, David K. Menon, David K. Menon, Michael P. Coleman, Michael P. Coleman   +8 more
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The Requirement of Sox2 for the Spinal Cord Motor Neuron Development of Zebrafish

Frontiers in Molecular Neuroscience, 2020
Sex-determining region Y box 2 (Sox2), expressed in neural tissues, plays an important role as a transcription factor not only in the pluripotency and proliferation of neuronal cells but also in the opposite function of cell differentiation. Nevertheless,
Jie Gong, Songqun Hu, Zigang Huang, Yuebo Hu, Xiaoning Wang, Jinxiang Zhao, Peipei Qian, Cheng Wang, Jiajing Sheng, Xiaofeng Lu, Guanyun Wei, Dong Liu, Dong Liu   +12 more
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