Results 1 to 10 of about 170,375 (242)

Species and Sex Differences in the Morphogenic Response of Primary Rodent Neurons to 3,3′-Dichlorobiphenyl (PCB 11)

open access: yesToxics, 2017
PCB 11 is an emerging global pollutant that we recently showed promotes axonal and dendritic growth in primary rat neuronal cell cultures. Here, we address the influence of sex and species on neuronal responses to PCB 11.
Sunjay Sethi   +2 more
doaj   +1 more source

Predicting the distribution of serotonergic axons: a supercomputing simulation of reflected fractional Brownian motion in a 3D-mouse brain model

open access: yesFrontiers in Computational Neuroscience, 2023
The self-organization of the brain matrix of serotonergic axons (fibers) remains an unsolved problem in neuroscience. The regional densities of this matrix have major implications for neuroplasticity, tissue regeneration, and the understanding of mental ...
Skirmantas Janušonis   +4 more
doaj   +1 more source

Large-Scale Mapping of Axonal Arbors Using High-Density Microelectrode Arrays

open access: yesFrontiers in Cellular Neuroscience, 2019
Understanding the role of axons in neuronal information processing is a fundamental task in neuroscience. Over the last years, sophisticated patch-clamp investigations have provided unexpected and exciting data on axonal phenomena and functioning, but ...
Torsten Bullmann   +10 more
doaj   +1 more source

A Stochastic Compartmental Model for Fast Axonal Transport [PDF]

open access: yes, 2011
In this paper we develop a probabilistic micro-scale compartmental model and use it to study macro-scale properties of axonal transport, the process by which intracellular cargo is moved in the axons of neurons.
McKinley, Scott A.   +2 more
core   +1 more source

Multiple Copies of microRNA Binding Sites in Long 3′UTR Variants Regulate Axonal Translation

open access: yesCells, 2023
Rapid responses to changes within subcellular compartments of highly polarized cells, such as neuron axons, depend on local translation and post-transcriptional regulation.
Luba Farberov   +7 more
doaj   +1 more source

The avian tectobulbar tract: development, explant culture, and effects of antibodies on the pattern of neurite outgrowth [PDF]

open access: yes, 1990
The tectobulbar tract is the first long-distance projecting fiber pathway to appear during the development of the avian optic tectum (dorsal half of the mesencephalon).
Kröger, Stephan, Schwarz, U.
core   +2 more sources

Uncovering Discrete Synaptic Proteomes to Understand Neurological Disorders

open access: yesProteomes, 2018
The mammalian nervous system is an immensely heterogeneous organ composed of a diverse collection of neuronal types that interconnect in complex patterns.
Yi-Zhi Wang, Jeffrey N. Savas
doaj   +1 more source

A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration [PDF]

open access: yes, 2012
Axonal degeneration is a molecular self-destruction cascade initiated following traumatic, toxic, and metabolic insults. Its mechanism underlies a number of disorders including hereditary and diabetic neuropathies and the neurotoxic side effects of ...
Bhattacharya, Martha R.C.   +7 more
core   +2 more sources

Pathway-like Activation of 3D Neuronal Constructs with an Optical Interface

open access: yesBiosensors
Three-dimensional neuronal organoids, spheroids, and tissue mimics are increasingly used to model cognitive processes in vitro. These 3D constructs are also used to model the effects of neurological and psychiatric disorders and to perform computational ...
Saeed Omidi, Yevgeny Berdichevsky
doaj   +1 more source

Human umbilical cord mesenchymal stem cells promote peripheral nerve repair via paracrine mechanisms

open access: yesNeural Regeneration Research, 2015
Human umbilical cord-derived mesenchymal stem cells (hUCMSCs) represent a promising young-state stem cell source for cell-based therapy. hUCMSC transplantation into the transected sciatic nerve promotes axonal regeneration and functional recovery.
Zhi-yuan Guo   +4 more
doaj   +1 more source

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