Results 21 to 30 of about 30,406 (272)

Conceptual Design and Parametric Optimization of a New Multileveled Horsetail Structure for Bicycle Helmets

open access: yesAdvanced Engineering Materials, EarlyView., 2023
This study aims to explore the feasibility of using a structure inspired by the features of horsetail and human spine as the potential helmet liner, targeting at mitigation of acceleration‐induced injuries. A parametric study is conducted to investigate the effect of individual geometrical variables in the design, indicating its capability to reduce ...
Bing Leng   +3 more
wiley   +1 more source

Estimating axon radius using diffusion-relaxation MRI: calibrating a surface-based relaxation model with histology [PDF]

open access: yesFrontiers in Neuroscience, Vol 17, 2023. https://www.frontiersin.org/articles/10.3389/fnins.2023.1209521, 2023
Axon radius is a potential biomarker for brain diseases and a crucial tissue microstructure parameter that determines the speed of action potentials. Diffusion MRI (dMRI) allows non-invasive estimation of axon radius, but accurately estimating the radius of axons in the human brain is challenging.
arxiv   +1 more source

Neuron Names: A Gene- and Property-Based Name Format, With Special Reference to Cortical Neurons

open access: yesFrontiers in Neuroanatomy, 2019
Precision in neuron names is increasingly needed. We are entering a new era in which classical anatomical criteria are only the beginning toward defining the identity of a neuron as carried in its name.
Gordon M. Shepherd   +14 more
doaj   +1 more source

Modeling of interstitial branching of axonal networks [PDF]

open access: yes1. J. Integr. Neurosci. 12, 1-14, (2013), 2013
A single axon can generate branches connecting with plenty synaptic targets. Process of branching is very important for making connections in central nervous system. The interstitial branching along primary axon shaft occurs during nervous system development. Growing axon makes pause in its movement and leaves active points behind its terminal. The new
arxiv   +1 more source

Interplay between kinesin-1 and cortical dynein during axonal outgrowth and microtubule organization in Drosophila neurons

open access: yeseLife, 2015
In this study, we investigated how microtubule motors organize microtubules in Drosophila neurons. We showed that, during the initial stages of axon outgrowth, microtubules display mixed polarity and minus-end-out microtubules push the tip of the axon ...
Urko del Castillo   +3 more
doaj   +1 more source

Pseudorabies Virus Mutants Lacking US9 Are Defective in Cytoplasmic Assembly and Sorting of Virus Particles into Axons and Not in Axonal Transport

open access: yesViruses, 2023
Herpes simplex virus (HSV) and varicella zoster virus (VZV) rely on transport of virus particles in neuronal axons to spread from sites of viral latency in sensory ganglia to peripheral tissues then on to other hosts.
Steven Adamou   +2 more
doaj   +1 more source

The impact of realistic axonal shape on axon diameter estimation using diffusion MRI [PDF]

open access: yes, 2020
To study axonal microstructure with diffusion MRI, axons are typically modeled as straight impermeable cylinders, whereby the transverse diffusion MRI signal can be made sensitive to the cylinder's inner diameter. However, the shape of a real axon varies along the axon direction, which couples the longitudinal and transverse diffusion of the overall ...
arxiv   +1 more source

Lmx1b is required at multiple stages to build expansive serotonergic axon architectures

open access: yeseLife, 2019
Formation of long-range axons occurs over multiple stages of morphological maturation. However, the intrinsic transcriptional mechanisms that temporally control different stages of axon projection development are unknown. Here, we addressed this question
Lauren J Donovan   +7 more
doaj   +1 more source

microRNAs in axon guidance [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2014
Brain wiring is a highly intricate process in which trillions of neuronal connections are established. Its initial phase is particularly crucial in establishing the general framework of neuronal circuits. During this early step, differentiating neurons extend axons, which reach their target by navigating through a complex environment with extreme ...
Iyer, A. N., Bellon, A., Baudet, M. L.
openaire   +3 more sources

Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking

open access: yeseLife, 2016
The mechanisms regulating synapse numbers during development and ageing are essential for normal brain function and closely linked to brain disorders including dementias. Using Drosophila, we demonstrate roles of the microtubule-associated protein Tau in
Andre Voelzmann   +6 more
doaj   +1 more source

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