Results 21 to 30 of about 171,690 (236)
eLife, 2016 The mechanisms regulating synapse numbers during development and ageing are essential for normal brain function and closely linked to brain disorders including dementias. Using Drosophila, we demonstrate roles of the microtubule-associated protein Tau in
Andre Voelzmann +6 more
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Local Accumulation of Axonal Mitochondria in the Optic Nerve Glial Lamina Precedes Myelination
Frontiers in Neuroanatomy, 2021 Mitochondria are essential for neurons and must be optimally distributed along their axon to fulfill local functions. A high density of mitochondria has been observed in retinal ganglion cell (RGC) axons of an unmyelinated region of the optic nerve ...
Samantha J. Wilkison +10 more
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Polychlorinated Biphenyls (PCBs): Risk Factors for Autism Spectrum Disorder?
Toxics, 2020 Autism spectrum disorder (ASD) includes a group of multifactorial neurodevelopmental disorders defined clinically by core deficits in social reciprocity and communication, restrictive interests and repetitive behaviors.
Harmanpreet Kaur Panesar +3 more
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Unrestrained growth of correctly oriented microtubules instructs axonal microtubule orientation
eLife, 2022 In many eukaryotic cells, directed molecular transport occurs along microtubules. Within neuronal axons, transport over vast distances particularly relies on uniformly oriented microtubules, whose plus-ends point towards the distal axon tip ...
Maximilian AH Jakobs +2 more
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Toxics, 2017 PCB 11 is an emerging global pollutant that we recently showed promotes axonal and dendritic growth in primary rat neuronal cell cultures. Here, we address the influence of sex and species on neuronal responses to PCB 11.
Sunjay Sethi +2 more
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The role of higher-order thalamus during learning and correct performance in goal-directed behavior
eLife, 2022 The thalamus is a gateway to the cortex. Cortical encoding of complex behavior can therefore only be understood by considering the thalamic processing of sensory and internally generated information.
Danilo La Terra +5 more
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Large-Scale Mapping of Axonal Arbors Using High-Density Microelectrode Arrays
Frontiers in Cellular Neuroscience, 2019 Understanding the role of axons in neuronal information processing is a fundamental task in neuroscience. Over the last years, sophisticated patch-clamp investigations have provided unexpected and exciting data on axonal phenomena and functioning, but ...
Torsten Bullmann +10 more
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Frontiers in Neural Circuits, 2022 Neurons in the mouse primary visual cortex (V1) exhibit characteristic response selectivity to visual stimuli, such as orientation, direction and spatial frequency selectivity. Since V1 receives thalamic visual inputs from the lateral geniculate nucleus (
Satoru Kondo +5 more
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Uncovering Discrete Synaptic Proteomes to Understand Neurological Disorders
Proteomes, 2018 The mammalian nervous system is an immensely heterogeneous organ composed of a diverse collection of neuronal types that interconnect in complex patterns.
Yi-Zhi Wang, Jeffrey N. Savas
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Interferon inhibits the release of herpes simplex virus-1 from the axons of sensory neurons
mBio, 2023 Herpes simplex virus-1 (HSV-1) has evolved mechanisms to evade the host immune system and limit the antiviral effects induced by interferon (IFN) produced by local epithelial and immune cells.
Kevin Danastas +6 more
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