Results 21 to 30 of about 188,959 (299)
Frontiers in Neural Circuits, 2022 Neurons in the mouse primary visual cortex (V1) exhibit characteristic response selectivity to visual stimuli, such as orientation, direction and spatial frequency selectivity. Since V1 receives thalamic visual inputs from the lateral geniculate nucleus (
Satoru Kondo +5 more
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Unrestrained growth of correctly oriented microtubules instructs axonal microtubule orientation
eLife, 2022 In many eukaryotic cells, directed molecular transport occurs along microtubules. Within neuronal axons, transport over vast distances particularly relies on uniformly oriented microtubules, whose plus-ends point towards the distal axon tip ...
Maximilian AH Jakobs +2 more
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eLife, 2016 The mechanisms regulating synapse numbers during development and ageing are essential for normal brain function and closely linked to brain disorders including dementias. Using Drosophila, we demonstrate roles of the microtubule-associated protein Tau in
Andre Voelzmann +6 more
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Local Accumulation of Axonal Mitochondria in the Optic Nerve Glial Lamina Precedes Myelination
Frontiers in Neuroanatomy, 2021 Mitochondria are essential for neurons and must be optimally distributed along their axon to fulfill local functions. A high density of mitochondria has been observed in retinal ganglion cell (RGC) axons of an unmyelinated region of the optic nerve ...
Samantha J. Wilkison +10 more
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The role of higher-order thalamus during learning and correct performance in goal-directed behavior
eLife, 2022 The thalamus is a gateway to the cortex. Cortical encoding of complex behavior can therefore only be understood by considering the thalamic processing of sensory and internally generated information.
Danilo La Terra +5 more
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NeuroImage, 2023 Diffusion MRI uses the random displacement of water molecules to sensitize the signal to brain microstructure and to properties such as the density and shape of cells. Microstructure modeling techniques aim to estimate these properties from acquired data
Björn Lampinen +9 more
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Resveratrol promotes axonal regeneration via PI3K/Akt pathway in rats after intracerebral hemorrhage
Di-san junyi daxue xuebao, 2019 Objective To investigate the mechanism by which resveratrol (RES) promotes axonal regeneration in rats after intracerebral hemorrhage (ICH) and explore the role of the PI3K/Akt pathway that regulates the AMPKα pathway.
WANG Guanyu +4 more
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The Genetics of Axonal Transport and Axonal Transport Disorders
PLoS Genetics, 2006 Neurons are specialized cells with a complex architecture that includes elaborate dendritic branches and a long, narrow axon that extends from the cell body to the synaptic terminal. The organized transport of essential biological materials throughout the neuron is required to support its growth, function, and viability.
Lawrence S.B. Goldstein, Jason E. Duncan
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Uncovering Discrete Synaptic Proteomes to Understand Neurological Disorders
Proteomes, 2018 The mammalian nervous system is an immensely heterogeneous organ composed of a diverse collection of neuronal types that interconnect in complex patterns.
Yi-Zhi Wang, Jeffrey N. Savas
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eLife, 2019 Cortical collapse factors affect microtubule (MT) dynamics at the plasma membrane. They play important roles in neurons, as suggested by inhibition of axon growth and regeneration through the ARF activator Efa6 in C.
Yue Qu +11 more
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