Results 51 to 60 of about 30,406 (272)

Neuronal Dynamics and Axonal Flow: Axonal Peristalsis [PDF]

Proceedings of the National Academy of Sciences, 1972
By time-lapse, phase-contrast cinemicrography of sensory nerve fibers of young mice, isolated with their originating spinal ganglia in nutrient solution, the postulated peristaltic surface drive of the cellulifugal propulsion of the semisolid axonal column at a rate of the order of 1 mm/day (1 μm/min) could be verified and quantitatively analyzed.
openaire   +3 more sources

The Regulation of Axon Diameter: From Axonal Circumferential Contractility to Activity-Dependent Axon Swelling [PDF]

Frontiers in Molecular Neuroscience, 2018
In the adult nervous system axon caliber varies widely amongst different tracts. When considering a given axon, its diameter can further fluctuate in space and time, according to processes including the distribution of organelles and activity-dependent mechanisms.
Ana Rita Costa, Rita Pinto-Costa, Rita Pinto-Costa, Mónica Mendes Sousa, Sara Castro Sousa   +4 more
openaire   +5 more sources

Visualisation of ribosomes in Drosophila axons using Ribo-BiFC

Biology Open, 2019
The distribution of assembled, and potentially translating, ribosomes within cells can be visualised in Drosophila by using Bimolecular Fluorescence Complementation (BiFC) to monitor the interaction between tagged pairs of 40S and 60S ribosomal proteins (
Anand K. Singh, Akilu Abdullahi, Matthias Soller, Alexandre David, Saverio Brogna   +4 more
doaj   +1 more source

Atypical Extracellular Action Potentials from Posteromedial Hypothalamus in Anesthetized Humans

Frontiers in Bioscience-Landmark, 2022
Background: We obtained microelectrode recordings from four patients with intractable aggressivity who underwent surgery at posteromedial hypothalamus under general anaesthesia.
Jesús Pastor, Lorena Vega-Zelaya, Elena Martín-Abad   +2 more
doaj   +1 more source

Species and Sex Differences in the Morphogenic Response of Primary Rodent Neurons to 3,3′-Dichlorobiphenyl (PCB 11)

Toxics, 2017
PCB 11 is an emerging global pollutant that we recently showed promotes axonal and dendritic growth in primary rat neuronal cell cultures. Here, we address the influence of sex and species on neuronal responses to PCB 11.
Sunjay Sethi, Kimberly P. Keil, Pamela J. Lein   +2 more
doaj   +1 more source

Large-Scale Mapping of Axonal Arbors Using High-Density Microelectrode Arrays

Frontiers in Cellular Neuroscience, 2019
Understanding the role of axons in neuronal information processing is a fundamental task in neuroscience. Over the last years, sophisticated patch-clamp investigations have provided unexpected and exciting data on axonal phenomena and functioning, but ...
Torsten Bullmann, Torsten Bullmann, Torsten Bullmann, Milos Radivojevic, Stefan T. Huber, Kosmas Deligkaris, Kosmas Deligkaris, Andreas Hierlemann, Urs Frey, Urs Frey, Urs Frey   +10 more
doaj   +1 more source

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao, Katherine R Schon, Jana Vandrovcova, Özlem Yayıcı Köken, Sharika Raga, Kireshnee Naidu, Maryke Schoonen, Nimita Rani, Pedro Tomaselli, Dipti Baskar, Musambo Kapapa, Ipek Polat, Lindsay A Wilson, Kumarasamy Thangaraj, Uluç Yiş, Bevinahalli N Nandeesh, David Bearden, Michelle Kvalsund, Franclo Henning, Seena Vengalil, Atchayaram Nalini, Claudia F. R. Sobreira, Wilson Marques, Haluk Topoloğlu, Michael G Hanna, Sireesha Yareeda, Venugopalan Y Vishnu, Francois H van der Westhuizen, Izelle Smuts, Surita Meldau, Jo Wilmshurst, Büşranur Çavdarlı, Jeannine Heckmann, Patrick F Chinnery, Rita Horvath   +34 more
wiley   +1 more source

Cytoplasmic cleavage of IMPA1 3′ UTR is necessary for maintaining axon integrity

Cell Reports, 2021
Summary: The 3′ untranslated regions (3′ UTRs) of messenger RNAs (mRNAs) are non-coding sequences involved in many aspects of mRNA metabolism, including intracellular localization and translation.
Catia Andreassi, Raphaëlle Luisier, Hamish Crerar, Marousa Darsinou, Sasja Blokzijl-Franke, Tchern Lenn, Nicholas M. Luscombe, Giovanni Cuda, Marco Gaspari, Adolfo Saiardi, Antonella Riccio   +10 more
doaj  

Neurorrhaphy in Presence of Polyethylene Glycol Enables Immediate Electrophysiological Conduction in Porcine Model of Facial Nerve Injury

Frontiers in Surgery, 2022
Facial nerve trauma often leads to disfiguring facial muscle paralysis. Despite several promising advancements, facial nerve repair procedures often do not lead to complete functional recovery.
Dmitriy Petrov, Dmitriy Petrov, Justin C. Burrell, Justin C. Burrell, Justin C. Burrell, Kevin D. Browne, Kevin D. Browne, Franco A. Laimo, Franco A. Laimo, Sanford E. Roberts, Sanford E. Roberts, Zarina S. Ali, D. Kacy Cullen, D. Kacy Cullen, D. Kacy Cullen   +14 more
doaj   +1 more source

An MRI assessment of mechanisms underlying lesion growth and shrinkage in multiple sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
By applying the tensor model, we analysed lesion orientation and the directionality of lesion expansion/contraction in multiple sclerosis. Each lesion is summarized as an ellipsoid, and the tensor model is applied to calculate lesion anisotropy. From the top to the bottom white matter atlas, surface‐in gradient segmentation and venous atlas used in the
Ermelinda De Meo, Ferran Prados Carrasco, J. William L. Brown, Alasdair J. Coles, Nick G. Cunniffe, Amy E. Jolly, Baris Kanber, Rebecca Samson, Frederik Barkhof, Declan Chard   +9 more
wiley   +1 more source