Results 61 to 70 of about 170,375 (242)
Metabolic reprogramming: a new option for the treatment of spinal cord injury
Neural Regeneration ResearchSpinal cord injuries impose a notably economic burden on society, mainly because of the severe after-effects they cause. Despite the ongoing development of various therapies for spinal cord injuries, their effectiveness remains unsatisfactory. However, a
Jiangjie Chen +13 more
doaj +1 more source
eLife, 2016 The mechanisms regulating synapse numbers during development and ageing are essential for normal brain function and closely linked to brain disorders including dementias. Using Drosophila, we demonstrate roles of the microtubule-associated protein Tau in
Andre Voelzmann +6 more
doaj +1 more source
The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh +22 more
wiley +1 more source
Neuron Names: A Gene- and Property-Based Name Format, With Special Reference to Cortical Neurons
Frontiers in Neuroanatomy, 2019 Precision in neuron names is increasingly needed. We are entering a new era in which classical anatomical criteria are only the beginning toward defining the identity of a neuron as carried in its name.
Gordon M. Shepherd +14 more
doaj +1 more source
On Λ-Fractional Derivative and Human Neural Network
Axioms, 2023 Fractional derivatives can express anomalous diffusion in brain tissue. Various brain diseases such as Alzheimer’s disease, multiple sclerosis, and Parkinson’s disease are attributed to the accumulation of proteins in axons.
D. Karaoulanis +3 more
doaj +1 more source
A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila. [PDF]
, 2011 The unique architecture of neurons requires the establishment and maintenance of polarity, which relies in part on microtubule-based transport to deliver essential cargo into dendrites.
Goldstein, Lawrence SB +3 more
core +2 more sources
Cytokine, Chemokine, and Neurofilament Light Chain Signatures in LGI1 Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To investigate the value of cytokine, chemokine, and neurofilament light chain (NfL) concentrations in predicting relapse risk, chronic epilepsy, and functional impairment in LGI1 autoimmune encephalitis (AE). Methods Cytokines/chemokines (IL‐1‐beta, IL‐2, IL‐4, IL‐5, IL‐6, IL‐8/CXCL8, IL‐10, IL‐12p70, IL‐13, IL‐17A, GM‐CSF, TNF ...
Albert Aboseif +17 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan +46 more
wiley +1 more source
Brain and Behavior, 2020 Introduction Posttraumatic scarring of peripheral nerves produces unwanted adhesions that block axonal growth. In the context of surgical nerve repair, the organization of the scar tissue adjacent to conduits used to span the gap between the stumps of ...
Jolanta Fertala +5 more
doaj +1 more source
Transplanted olfactory ensheathing cells promote regeneration of cut adult rat optic nerve axons [PDF]
, 2003 Transplantation of olfactory ensheathing cells into spinal cord lesions promotes regeneration of cut axons into terminal fields and functional recovery.
Li, D. +4 more
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