Results 11 to 20 of about 615 (149)
Reagent-controlled regiodivergent ring expansions of steroids. [PDF]
Nat Commun, 2018 Ring expansion provides a powerful way of introducing a heteroatom substituent into a carbocyclic framework. However, such reactions are often limited by the tendency of a given substrate to afford only one of the two rearrangement products or fail to ...
Charaschanya M, Aubé J.
europepmc +5 more sources
Synthetic routes to 9-azasteroids [PDF]
, 1975 Syntheses of azasteroids both from natural steroids and from precursors bearing a nitrogen atom are reviewed. The present research was directed towards the preparation of suitable tricyclic compounds possessing the future A-,B- and D-rings of a 9 ...
Eason, John M M
core +3 more sources
A microwave promoted and Lewis acid catalysed solventless approach to 4-azasteroids [PDF]
Steroids, 2008 The preparation of 3-oxo-4-azasteroid fromA-nor-3,5-secosteroid-3-oic acid is described in a solventless condition catalysed by Lewis acid under microwave irradiation.We utilized urea as an environmentally benign source for the generation of ammonia ...
Borthakur, M, Boruah, R C
exaly +2 more sources
Synthetic approaches to 9-azasteroids [PDF]
, 1968 An account is given of total syntheses of azasteroids, syntheses of 4-piperidones, and also syntheses of 2-quinolizidones. l,2,3,4,5,6-Hexahydro-3-oxo-4aH-benzo[c]quinolizine was prepared and methylation shown to occur in the 2-position which was of no ...
core +2 more sources
Clinical and Translational Medicine, Volume 10, Issue 8, December 2020., 2020 Schematic representation of cause, exacerbation and consequence of vaccines‐induced diverse immune disorders in immune‐responsive or immune‐privileged tissues. It depicts that vaccination of the unborn, alter biology of trophoblast‐embryo‐fetus‐placenta and orderly growth and development affecting epithelial‐mesenchymal transition, proper expression of
Mahin Khatami
wiley +1 more source
Can ion mobility mass spectrometry and density functional theory help elucidate protonation sites in 'small' molecules? [PDF]
, 2013 Ion mobility spectrometry-mass spectrometry (IMS-MS) offers an opportunity to combine measurements and/or calculations of the collision cross-sections and subsequent mass spectra with computational modelling in order to derive the three-dimensional ...
Chowdhry, Babur Z. +4 more
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Journal of Spectroscopy, Volume 2013, Issue 1, 2013., 2013 The present paper reports the synthesis and spectroscopic characterization of few N‐2′‐hydroxyethyl‐substituted azacholestanes using BF3‐OEt2, TiCl4, SnCl4, and H2SO4 as catalysts in moderate yields by a modified version of Schmidt reaction. A notable feature is the passivity of SnCl4 in case of 3β‐acetoxy‐N‐2′‐hydroxyethyl‐6‐aza‐B‐homo‐5α‐cholestan‐7 ...
Shahab A. A. Nami +6 more
wiley +1 more source
Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives [PDF]
, 2010 Background A maximum entropy approach is proposed to predict the cytotoxic effects of a panel of colchicine derivatives in several human cancer cell lines.
Chih-Yuan Tseng +7 more
core +1 more source
Steroidal 5α-Reductase: A Therapeutic Target for Prostate Disorders [PDF]
, 2021 Steroidal 5α-reductase is a system of NADPH dependent enzyme that catalyzes the irreversible conversion of Δ4–3-ketosteroid precursor (testosterone) to its corresponding 5α-reduced metabolite (dihydrotestosterone).
Dhingra, Neelima
core +2 more sources
Synthesis of 5-azaandrostane-3b,17b-diol protected at the 17b-hydroxyl group [PDF]
Journal of the Serbian Chemical Society, 2004 In the present paper, the preparation of 3b-hydroxy-17b-dimethyl-tert-butylsilyloxy-5-azaandrostane (15) in fourteen steps is described. B-nor-17-oxoandrost-5-en-3b-yl acetate (1) was used as the starting material, which was transformed to the key ...
JAROSLAV KALVODA +4 more
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