Syntheses and antimicrobial activities of some 4-aza-sitostane derivatives [PDF]
, 1969 Research into the chemical and pharmacological properties of azasteroids has become of interest because of their potential value as pharmacodynamic and chemotherapeutic agents. A nitrogen atom, for example, would be able to interact, unlike carbon, with
Aboul-Enein, Hassan Y.
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Synthesis and reactions of 4-azasteroidal alkylating agents: approaches to related 5-azasteroids
, 1986 Bibliography: p. 178-203.
openaire +2 more sources
A Chemoproteomic Approach to Elucidate the Mechanism of Action of 6-Azasteroids with Unique Activity in Mycobacteria. [PDF]
ACS Infect Dis, 2023 Werman JM +4 more
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Inhibitors of 3&beta-Hydroxysteroid? Dehydrogenase and Metabolic? and Enzymatic Characterization of the Cholesterol? ? Metabolizing Intracellular Growth? Operon? of? Mycobacterium tuberculosis [PDF]
, 2012 New drugs with novel mechanisms of action are required to meet the severe threat to human health posed by the emergence of multidrug and extensively drug resistant strains of Mycobacterium tuberculosis (M. tuberculosis).
Thomas, Suzanne T.
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Assessment of the Potential Biological Activity of Low Molecular Weight Metabolites of Freshwater Macrophytes with QSAR [PDF]
, 2016 The paper focuses on the assessment of the spectrum of biological activities (antineoplastic, anti-inflammatory, antifungal, and antibacterial) with PASS (Prediction of Activity Spectra for Substances) for the major components of three macrophytes ...
Elena V. Fedorova +3 more
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Characterization of 3?-hydroxysteroid dehydrogenase (Rv1106c) and the sterol metabolic pathway in Mycobacterium tuberculosis (M. tb) [PDF]
, 2011 [to be ...
Yang, Xinxin
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Skeletal metalation of lactams through a carbonyl-to-nickel-exchange logic. [PDF]
Nat Commun, 2023 Zhong H +7 more
europepmc +1 more source
Azoarene activation for Schmidt-type reaction and mechanistic insights. [PDF]
Nat Commun, 2022 Meng FT +8 more
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MICROBIAL OXIDATION OF FINASTERIDE WITH MACROPHOMINA PHASEOLINA(KUCC 730) [PDF]
, 2017 Objectives: New  microbial oxidative derivatives of Finasteride [17β-(N-tert-butylcarbamoyl)-4-aza-5α-androst-1-en-3-one] (1) has been investigated with Macrophomina phaseolina (ATCC730).Methods: Fermented media of  Macrophomina phaseolina (ATCC730 ...
Ashraf, Muhammad +4 more
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Acyl radical cascade reactions: the synthesis of azasteroids [PDF]
Our work has been concerned with the synthesis of azasteroid ring systems, utilising acyl radical cascade reactions. Chapter 1 comprises an overview of published work relevant to our studies: an analysis of steroid biosynthesis and synthesis; a review of
Double, Philip John
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