Results 1 to 10 of about 116,499 (253)

Facile fabrication of polymer network using click chemistry and their computational study [PDF]

Royal Society Open Science, 2021
Click reaction is a very fast, high yield with no by-product, biocompatible, tolerant to surrounded medium, and very specific cycloaddition reaction between azides and alkynes to form triazole.
Md. Kausar Ahmed, Ajoy Kumer, Abu Bin Imran   +2 more
doaj   +1 more source

Azide-Alkyne Cycloaddition Catalyzed by a Glucose/Benedict Reagent System

Chemistry Proceedings, 2021
Benedict’s Reagent is commonly used in identifying reducing sugars through a redox process where a Cu(I) species is generated. Despite the simplicity of this reaction, this has barely been investigated as a copper (I) source for catalytic processes.
Jesús G. García Torres, Andrés F. Becerra-Buitrago, Luis Carlos García-Sánchez, Marco A. García-Eleno, M. V. Basavanag Unnamatla, Erick Cuevas-Yañez   +5 more
doaj   +1 more source

The Azide-Allene Dipolar Cycloaddition: Is DFT Able to Predict Site- and Regio-Selectivity?

Molecules, 2021
The site- and regio-selectivity of thermal, uncatalysed 1,3-dipolar cycloadditions between arylazides and mono- or tetra-substituted allenes with different electronic features have been investigated by both conceptual (reactivity indices) and ...
Giorgio Molteni, Alessandro Ponti
doaj   +1 more source

Design, Synthesis and Biological Evaluation of Syn and Anti-like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action

Molecules, 2022
Our investigation includes the synthesis of new naphthalene-bis-triazole-bis-quinolin-2(1H)-ones 4a–e and 7a–e via Cu-catalyzed [3 + 2] cycloadditions of 4-azidoquinolin-2(1H)-ones 3a–e with 1,5-/or 1,8-bis(prop-2-yn-1-yloxy)naphthalene (2) or (6).
Essmat M. El-Sheref, Mohamed A. Ameen, Kamal M. El-Shaieb, Fathy F. Abdel-Latif, Asmaa I. Abdel-naser, Alan B. Brown, Stefan Bräse, Hazem M. Fathy, Iqrar Ahmad, Harun Patel, Hesham A. M. Gomaa, Bahaa G. M. Youssif, Asmaa H. Mohamed   +12 more
doaj   +1 more source

HUISGEN AND HIS ADVENTURES IN A PLAYGROUND OF MECHANISMS AND NOVEL REACTIONS [PDF]

Química Nova, 2021
The death of professor Rolf Huisgen (1920-2020) was announced on March 26th 2020, in the midst of the COVID-19 pandemic. Professor Huisgen was professor emeritus at the University of Munich in Germany, and studied in detail the mechanism of the 1,3 ...
Daniel T. G. Gonzaga, Luana da S. M. Forezi, Carolina G. de S. Lima, Patricia G. Ferreira, Fernando de C. da Silva, Vitor F. Ferreira   +5 more
doaj   +1 more source

Facile and Scalable Route to Access Rare Deoxy Amino Sugars for Nonulosonic Acid Aldolase Biosynthesis

Frontiers in Chemistry, 2022
We presented a facile and scalable route for the synthesis of di-azido sugars via one-pot double inversion of the mono-benzoyl sugars by TBAN3 and studied the dependency pattern between solvent and protecting groups as well as the configuration of the ...
Yixuan Zhou, Kuo-Shiang Liao, Shiou-Ting Li, Chung-Yi Wu   +3 more
doaj   +1 more source

Lead(II)-Azido Metal–Organic Coordination Polymers: Synthesis, Structure and Application in PbO Nanomaterials Preparation

Nanomaterials, 2022
The current study aims to explain recent developments in the synthesis of Pb(II)-azido metal-organic coordination polymers. Coordination polymers are defined as hybrid materials encompassing metal-ion-based, organic linkers, vertices, and ligands ...
Jaber Dadashi, Mohammad Khaleghian, Younes Hanifehpour, Babak Mirtamizdoust, Sang Woo Joo   +4 more
doaj   +1 more source

Crystal structure of 6-azido-6-deoxy-1,2-O-isopropylidene-α-d-glucofuranose

Acta Crystallographica Section E: Crystallographic Communications, 2020
Short syntheses to high Fsp3 index natural-product analogues such as iminosugars are of paramount importance in the investigation of their biological activities and reducing the use of protecting groups is an advantageous synthetic strategy.
Adam Wood, Paul V. Bernhardt, Ian van Altena, Michela I. Simone   +3 more
doaj   +1 more source

Oligonucleotide Tagging for Copper-Free Click Conjugation

Molecules, 2013
Copper-free click chemistry between cyclooctynes and azide is a mild, fast and selective technology for conjugation of oligonucleotides. However, technology for site-specific introduction of the requisite probes by automated protocols is scarce, while ...
Alan Rowan, Floris L. van Delft, John C. Hodges, Nancy S. Barta, Brian Gibson, Anup M. Jawalekar, Jorge M. M. Verkade, Sudip Malik   +7 more
doaj   +1 more source

Chemical Architecture and Applications of Nucleic Acid Derivatives Containing 1,2,3-Triazole Functionalities Synthesized via Click Chemistry

Molecules, 2012
There is considerable attention directed at chemically modifying nucleic acids with robust functional groups in order to alter their properties. Since the breakthrough of copper-assisted azide-alkyne cycloadditions (CuAAC), there have been several ...
Wei Gong, Tim Efthymiou, Jean-Paul Desaulniers   +2 more
doaj   +1 more source