Results 211 to 220 of about 132,389 (268)

A Noncovalent Click‐to‐Release Strategy to Control Bond Cleavage and Prodrug Activation

Angewandte Chemie, EarlyView.
Extending the click‐to‐release concept beyond covalent ligation, we introduce a noncovalent click‐to‐release strategy based on cucurbituril‐adamantane (CB‐Ad) association. A supramolecular preassembly encapsulating a self‐immolative guest (SIG) is rationally designed to prevent premature release, while adding a high‐affinity Ad guest initiates the CB ...
Xuancheng Fu, Bowen Xu, Suman Maity, Michelle Wu, Luke G. Westbrook, James H. Henderson, Yaoying Wu, Katie A. Edwards, Atanu Acharya, Xiaoran Hu   +9 more
wiley   +1 more source

Independent validation of transgenerational inheritance of learned pathogen avoidance in <i>Caenorhabditis elegans</i>. [PDF]

Elife
Akinosho A, Alexander J, Floyd K, Vidal-Gadea AG.   +3 more
europepmc   +1 more source

Membrane‐Penetrating Molecular Device Based on a Triplex Containing Acyclic L‐Threoninol Nucleic Acid Functionalized with Cholesterol

Angewandte Chemie, EarlyView.
A membrane‐penetrating molecular device composed of triplex containing cholesterol‐modified acyclic L‐threoninol nucleic acid (L‐aTNA) was achieved. This device is applied to a photo‐triggered signal transduction system functioning on giant unilamellar vesicles. Abstract Membrane‐penetrating molecular devices are valuable biological tools.
Kaifu Liu, Hiroyuki Asanuma, Keiji Murayama   +2 more
wiley   +1 more source

Optimization of the genetic code expansion technology for intracellular labelling and single-molecule tracking of proteins in genomically re-coded <i>E. coli</i>. [PDF]

RSC Chem Biol
Ilievski F, Wikström L, Borg A, Volkov IL, Brandis G, Johansson M.   +5 more
europepmc   +1 more source

An Engineered Aryl Azide Ligase for Site‐Specific Mapping of Protein–Protein Interactions through Photo‐Cross‐Linking

, 2008
Hemanta Baruah, Sujiet Puthenveetil, Yoon‐Aa Choi, Samit Shah, Alice Y. Ting   +4 more
openalex   +2 more sources

An Expanded Toolbox for Versatile Chemical Editing of Adeno‐Associated Virus

Angewandte Chemie, EarlyView.
We describe technology to introduce diverse non‐natural chemical functionalities site‐specifically into the capsid of adeno‐associated virus through genetic code expansion, and using them to engineer this leading vector for human gene therapy for enhanced tissue specificity and reduced immunogenicity Abstract Site‐specific incorporation of noncanonical
Quan Pham, Jake Glicksman, Boyang Han, David Koo, Conor Loynd, Soumya Jyoti Singha Roy, Abhishek Chatterjee   +6 more
wiley   +1 more source

A powerful bioorthogonal toolbox boosting the development of immune theranostics. [PDF]

Chem Sci
Liu S, Hua C, Li X, Yuan P, Xing B.
europepmc   +1 more source

Reaction of Sodium Azide with 1,1'–Dicyclohexenyl–Diepoxides

, 2003
Mohammad Raouf Darvich, Abolfazl Olyai, Akbar Shabanikia, Dariush Farkhani   +3 more
openalex   +1 more source

ChemInform Abstract: Reductive Azidation of Carbonyl Compounds via Tosylhydrazone Intermediates Using Sodium Azide.

, 2012
José Barluenga, María Tomás‐Gamasa, Carlos Valdés   +2 more
openalex   +2 more sources

Stable BF2 Boracycles as Versatile Reagents for Selective Ortho C–H Functionalization

Angewandte Chemie, EarlyView.
We report a robust, metal‐free and scalable synthesis of stable BF2 boracycles via directed ortho CH borylation, delivering isolable, shelf‐stable reagents without chromatographic purification. These BF2 boracycles exhibit unique and tunable reactivity, enabling highly selective ipso‐functionalization across a broad range of transformations.
Ganesh H. Shinde, Jonatan Babiker, Michelle Mebrahtu, Anaïs Prigent, Gauthier Foucras, Yogesh N. Aher, Francoise M. Amombo Noa, Magnus J. Johansson, Janez Košmrlj, Ross D. Jansen‐van Vuuren, Thomas Cailly, Henrik Sundén   +11 more
wiley   +1 more source