Results 141 to 150 of about 18,930 (288)
An Engineered Supramolecular Pathway for Enhanced Electrochemiluminescence
Advanced Science, EarlyView.A supramolecular electrochemiluminescent (ECL) system is presented in which cucurbit[7]uril (CB7) is covalently linked to [Ru(bpy)3]2+, forming a recognition‐responsive emitter. Host‒guest preorganization of tri‐n‐propylamine enables intramolecular ECL, boosting intensity by 162% compared to the standard system.
Maria Vittoria Balli +7 more
wiley +1 more source
Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology
Advanced Science, EarlyView.Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen +12 more
wiley +1 more source
Advanced Science, EarlyView.(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen +13 more
wiley +1 more source
Loss of Intestinal MSTN Promotes GLP‐1 Secretion Through SGLT1 Palmitoylation
Advanced Science, EarlyView.Intestinal MSTN deficiency enhances glucose‐stimulated GLP‐1 secretion and glucose tolerance in high‐fat diet‐fed mice. Mechanistically, loss of MSTN promotes YY1‐associated ZDHHC20 expression, increasing SGLT1 S‐palmitoylation at Cys301 and its plasma membrane localization in L cells.
Sheng‐Zhong Han +16 more
wiley +1 more source
Вестник Кемеровского государственного университета, 2013 The paper addresses the kinetics of the expansionn of lead and silver azides whiskers under photoand electricfield effects. The significant influence of charge heterogeneities (strong fielddomains) on the formation of solid (metal) and gas (nitrogen ...
F. I. Ivanov
doaj
Advanced Science, EarlyView.Secreted glycoproteins report on cellular state faster than the cell surface, yet remain hard to measure. The Enzyme‐Linked Cycloaddition Assay (ELCA) combines metabolic azide labeling with click chemistry in an ELISA‐like microplate format, resolving sialylation changes within minutes for 1‐2 EUR per sample.
Jon Lundstrøm +2 more
wiley +1 more source
Properties of azide-catalase [PDF]
Biochemical Journal, 1945 D, Keilin, E F, Hartree
openaire +2 more sources
Advanced Science, EarlyView.Tools for controlled selenol delivery are crucial for exploring Se‐related biology and medicine, but compound platforms for triggerable release of CH3SeH remain lacking. Herein, we report the first general triggered platform (TD‐MSe) for efficient cyclization release of CH3SeH in live cells.
Wenfang Liang +7 more
wiley +1 more source
Advanced Science, EarlyView.ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li +14 more
wiley +1 more source
Photoelectrocatalytic Diazidation of Olefins via Synergistic Dual Iron Species
Advanced Science, EarlyView.We report a simple and general approach for 1,2‐diazidation of alkenes by a photoelectrochemical strategy using TMSN3 as an azide source. This transformation proceeds using earth‐abundant iron under mild reaction conditions. It displays broad functional group compatibility and accommodates diverse alkene types‐including unactivated, activated, electron‐
Zhi‐Peng Guan +6 more
wiley +1 more source